Prointerleukin-18 is activated by meprin beta in vitro and in vivo in intestinal inflammation.
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Meprins process matrix metalloproteinase-9 (MMP-9)/gelatinase B and enhance the activation kinetics by MMP-3MEP1A allele for meprin A metalloprotease is a susceptibility gene for inflammatory bowel diseaseInterleukin-1 Family Cytokines in Liver DiseasesStructural basis for the sheddase function of human meprin metalloproteinase at the plasma membraneLet it flow: Morpholino knockdown in zebrafish embryos reveals a pro-angiogenic effect of the metalloprotease meprin alpha2.ADAM10 is the major sheddase responsible for the release of membrane-associated meprin A.Enhanced activity of meprin-α, a pro-migratory and pro-angiogenic protease, in colorectal cancer.Balance of meprin A and B in mice affects the progression of experimental inflammatory bowel disease.Isoform-specific interactions between meprin metalloproteases and the catalytic subunit of protein kinase A: significance in acute and chronic kidney injury.Metalloprotease meprin beta generates nontoxic N-terminal amyloid precursor protein fragments in vivo.Proteomic analyses reveal an acidic prime side specificity for the astacin metalloprotease family reflected by physiological substratesVillin and actin in the mouse kidney brush-border membrane bind to and are degraded by meprins, an interaction that contributes to injury in ischemia-reperfusionThe substrate degradome of meprin metalloproteases reveals an unexpected proteolytic link between meprin β and ADAM10.The metalloproteases meprin α and meprin β: unique enzymes in inflammation, neurodegeneration, cancer and fibrosis.Post-transcriptional regulation of meprin α by the RNA-binding proteins Hu antigen R (HuR) and tristetraprolin (TTP)Meprin A metalloproteinase and its role in acute kidney injury.Meprin A and meprin alpha generate biologically functional IL-1beta from pro-IL-1betaMeprin A metalloproteases enhance renal damage and bladder inflammation after LPS challenge.Hypoxia Associated Proteolytic Processing of OS-9 by the Metalloproteinase Meprin β.Interleukin-18 and IL-18 binding protein.Meprin metalloproteases inactivate interleukin 6.Meprin Metalloproteases Generate Biologically Active Soluble Interleukin-6 Receptor to Induce Trans-Signaling.Hepatitis regulation by the inflammasome signaling pathway.The Metalloprotease Meprin β Is an Alternative β-Secretase of APP.Meprin Metalloprotease Deficiency Associated with Higher Mortality Rates and More Severe Diabetic Kidney Injury in Mice with STZ-Induced Type 1 Diabetes.Proteolytic processing and inactivation of CCL2/MCP-1 by meprins.Determination of cleavage site of Reelin between its sixth and seventh repeat and contribution of meprin metalloproteases to the cleavage.The metalloprotease meprin β generates amino terminal-truncated amyloid β peptide species.Interleukin-18: Biological properties and role in disease pathogenesis.Shedding light on designing potential meprin β inhibitors through ligand-based robust validated computational approaches: A proposal to chemists!Undiagnosed Kidney Injury in Uninsured and Underinsured Diabetic African American Men and Putative Role of Meprin Metalloproteases in Diabetic Nephropathy.
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P2860
Prointerleukin-18 is activated by meprin beta in vitro and in vivo in intestinal inflammation.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Prointerleukin-18 is activated ...... vo in intestinal inflammation.
@en
type
label
Prointerleukin-18 is activated ...... vo in intestinal inflammation.
@en
prefLabel
Prointerleukin-18 is activated ...... vo in intestinal inflammation.
@en
P2860
P356
P1476
Prointerleukin-18 is activated ...... vo in intestinal inflammation.
@en
P2093
Judith S Bond
Sanjita Banerjee
P2860
P304
31371-31377
P356
10.1074/JBC.M802814200
P407
P577
2008-09-11T00:00:00Z