Polarization of the effects of autoimmune and neurodegenerative risk alleles in leukocytes. - Wikidata - wikimedia - TriplyDB

Polarization of the effects of autoimmune and neurodegenerative risk alleles in leukocytes.

Polarization of the effects of autoimmune and neurodegenerative risk alleles in leukocytes.

http://www.wikidata.org/entity/Q37012919

about

Genetics and immunity in the era of single-cell genomics Autoimmune diseases - connecting risk alleles with molecular traits of the immune system.Myeloid Dendritic Cells are Potential Players in Human Neurodegenerative Diseases Molecular control of activation and priming in macrophages Expression Quantitative Trait Loci Information Improves Predictive Modeling of Disease Relevance of Non-Coding Genetic Variation The TNF-family cytokine TL1A: from lymphocyte costimulator to disease co-conspirator Utilizing population variation, vaccination, and systems biology to study human immunology Exploiting genomics and natural genetic variation to decode macrophage enhancers Mechanisms Underlying the Selection and Function of Macrophage-Specific Enhancers M1 and M2 immune activation in Parkinson's Disease: Foe and ally?MT-HESS: an efficient Bayesian approach for simultaneous association detection in OMICS datasets, with application to eQTL mapping in multiple tissues A survey of best practices for RNA-seq data analysis Vitamin D Actions on CD4(+) T Cells in Autoimmune Disease The selection and function of cell type-specific enhancers A pharmacogenetic study implicates SLC9a9 in multiple sclerosis disease activity C5orf30 is a negative regulator of tissue damage in rheumatoid arthritis Genetic variants in Alzheimer disease - molecular and brain network approaches Sharing and Specificity of Co-expression Networks across 35 Human Tissues Genetics of gene expression in immunity to infection Exploring the nexus of Alzheimer's disease and related dementias with cancer and cancer therapies: A convening of the Alzheimer's Association & Alzheimer's Drug Discovery Foundation.Large-Scale Exome-wide Association Analysis Identifies Loci for White Blood Cell Traits and Pleiotropy with Immune-Mediated Diseases.Alzheimer's Disease Risk Polymorphisms Regulate Gene Expression in the ZCWPW1 and the CELF1 Loci.Regulation of gene expression in autoimmune disease loci and the genetic basis of proliferation in CD4+ effector memory T cells Prostaglandin signaling suppresses beneficial microglial function in Alzheimer's disease models.Neuroinflammation - using big data to inform clinical practice.Late onset Alzheimer's disease genetics implicates microglial pathways in disease risk.An independent component analysis confounding factor correction framework for identifying broad impact expression quantitative trait loci Genetics of rheumatoid arthritis susceptibility, severity, and treatment response.Variation and genetic control of gene expression in primary immunocytes across inbred mouse strains.Conserved epigenomic signals in mice and humans reveal immune basis of Alzheimer's disease.The genetic architecture of the human immune system: a bioresource for autoimmunity and disease pathogenesis.Targeted GAS6 delivery to the CNS protects axons from damage during experimental autoimmune encephalomyelitis Enhancer variants: evaluating functions in common disease.A genetic study on C5-TRAF1 and progression of joint damage in rheumatoid arthritis UBE2L3 polymorphism amplifies NF-κB activation and promotes plasma cell development, linking linear ubiquitination to multiple autoimmune diseases.An epidemiological perspective of personalized medicine: the Estonian experience.Cross-population joint analysis of eQTLs: fine mapping and functional annotation.Toll-like receptor expression in the blood and brain of patients and a mouse model of Parkinson's disease Pathophysiology of T follicular helper cells in humans and mice A TREM1 variant alters the accumulation of Alzheimer-related amyloid pathology.

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P2860

Polarization of the effects of autoimmune and neurodegenerative risk alleles in leukocytes.

http://www.wikidata.org/entity/Q37012919

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on May 2014

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Polarization of the effects of ...... ve risk alleles in leukocytes.

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Polarization of the effects of ...... ve risk alleles in leukocytes.

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Polarization of the effects of ...... ve risk alleles in leukocytes.

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SCIENCE.1249547

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Polarization of the effects of ...... ve risk alleles in leukocytes.

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Alina Von Korff

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Christophe Benoist

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Chun Ye

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Cristin McCabe

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Diane Mathis

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Gyan P Srivastava

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Hyun-il Paik

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Irene Frohlich

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Katie Rothamel

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Mark N Lee

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P2860

Trait-associated SNPs are more likely to be eQTLs: annotation to enhance discovery from GWAS

Potential etiologic and functional implications of genome-wide association loci for human diseases and traits

An integrated encyclopedia of DNA elements in the human genome

An integrated map of genetic variation from 1,092 human genomes

Statistical significance for genomewide studies

Characterizing the genetic basis of transcriptome diversity through RNA-sequencing of 922 individuals

A statistical framework for joint eQTL analysis in multiple tissues

Systematic identification of trans eQTLs as putative drivers of known disease associations

Systematic localization of common disease-associated variation in regulatory DNA

Mechanisms underlying inflammation in neurodegeneration

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10.1126/SCIENCE.1249547

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6183

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344

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David A. Hafler

Barbara E. Stranger

Nikolaos A. Patsopoulos

Joseph M Replogle

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2014-05-01T00:00:00Z

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262017308

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24786080

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neurodegeneration

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