Xenoreceptors CAR and PXR activation and consequences on lipid metabolism, glucose homeostasis, and inflammatory response.
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Contributions of metabolic dysregulation and inflammation to nonalcoholic steatohepatitis, hepatic fibrosis, and cancerThe paradox of progress: environmental disruption of metabolism and the diabetes epidemicPredictive Power Estimation Algorithm (PPEA)--a new algorithm to reduce overfitting for genomic biomarker discoveryThe brain dopaminergic system as an important center regulating liver cytochrome P450 in the rat.The DHR96 nuclear receptor controls triacylglycerol homeostasis in Drosophila.Proteasomal interaction as a critical activity modulator of the human constitutive androstane receptor.Effects of hepatic drug-metabolizing enzyme induction on clinical pathology parameters in animals and man.Evolutionary history and functional characterization of the amphibian xenosensor CAR.Pregnane X Receptor (PXR) expression in colorectal cancer cells restricts irinotecan chemosensitivity through enhanced SN-38 glucuronidation.Elucidating the 'Jekyll and Hyde' nature of PXR: the case for discovering antagonists or allosteric antagonists.Constitutive androstane receptor ligands modulate the anti-tumor efficacy of paclitaxel in non-small cell lung cancer cells.Gender disparity of hepatic lipid homoeostasis regulated by the circadian clockRational quantitative structure-activity relationship (RQSAR) screen for PXR and CAR isoform-specific nuclear receptor ligands.Xenobiotic metabolism, disposition, and regulation by receptors: from biochemical phenomenon to predictors of major toxicitiesPregnane X receptor modulates the inflammatory response in primary cultures of hepatocytesNuclear receptors in nonalcoholic Fatty liver diseaseArsenic decreases RXRα-dependent transcription of CYP3A and suppresses immune regulators in hepatocytes.SUMOylation and Ubiquitylation Circuitry Controls Pregnane X Receptor Biology in Hepatocytes.Prenatal perfluoroalkyl substance exposure and child adiposity at 8 years of age: The HOME study.Obesity and metabolic comorbidities: environmental diseases?Genome-wide detection of CNVs in Chinese indigenous sheep with different types of tails using ovine high-density 600K SNP arraysIdentification of Ginkgo biloba as a novel activator of pregnane X receptor.Analysis of endocrine disruption in Southern California coastal fish using an aquatic multispecies microarray.Metabolomics reveals a novel vitamin E metabolite and attenuated vitamin E metabolism upon PXR activation.Nuclear receptors as therapeutic targets in cholestatic liver diseases.Regulation of tissue-specific carboxylesterase expression by pregnane x receptor and constitutive androstane receptor.Protein expression analysis of inflammation-related colon carcinogenesis.Activation of pregnane X receptor (PXR) and constitutive androstane receptor (CAR) by herbal medicines.Sterol regulation of metabolism, homeostasis, and development.Targeting nuclear receptors with marine natural products.Overexpression of pregnane X and glucocorticoid receptors and the regulation of cytochrome P450 in human epileptic brain endothelial cells.Regulation of drug-metabolizing cytochrome P450 enzymes by glucocorticoids.Xenobiotic receptor humanized mice and their utility.Nuclear receptors in the cross-talk of drug metabolism and inflammation.Oxidative stress in the carcinogenicity of chemical carcinogens.Advantages of cell-based high-volume screening assays to assess nuclear receptor activation during drug discovery.The novel antibacterial compound walrycin A induces human PXR transcriptional activityPreliminary evaluation of gene expression profiles in liver of mice exposed to Taihu Lake drinking water for 90 days.Nuclear hormone receptors: Roles of xenobiotic detoxification and sterol homeostasis in healthy aging.The identification of nuclear receptors associated with hepatic steatosis to develop and extend adverse outcome pathways.
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Xenoreceptors CAR and PXR activation and consequences on lipid metabolism, glucose homeostasis, and inflammatory response.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 27 December 2007
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Xenoreceptors CAR and PXR acti ...... is, and inflammatory response.
@en
Xenoreceptors CAR and PXR acti ...... is, and inflammatory response.
@nl
type
label
Xenoreceptors CAR and PXR acti ...... is, and inflammatory response.
@en
Xenoreceptors CAR and PXR acti ...... is, and inflammatory response.
@nl
prefLabel
Xenoreceptors CAR and PXR acti ...... is, and inflammatory response.
@en
Xenoreceptors CAR and PXR acti ...... is, and inflammatory response.
@nl
P2093
P356
P1476
Xenoreceptors CAR and PXR acti ...... sis, and inflammatory response
@en
P2093
Amélie Moreau
Marie José Vilarem
Patrick Maurel
P356
10.1021/MP700103M
P407
P577
2007-12-27T00:00:00Z