Ras- and PI3K-dependent breast tumorigenesis in mice and humans requires focal adhesion kinase signaling. - Wikidata - wikimedia - TriplyDB

Ras- and PI3K-dependent breast tumorigenesis in mice and humans requires focal adhesion kinase signaling.

Ras- and PI3K-dependent breast tumorigenesis in mice and humans requires focal adhesion kinase signaling.

http://www.wikidata.org/entity/Q37073729

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Cas proteins: dodgy scaffolding in breast cancer CAS proteins in normal and pathological cell growth control NEDD9 promotes oncogenic signaling in mammary tumor development.Bone Metastasis from Renal Cell Carcinoma FAK in cancer: mechanistic findings and clinical applications Apc mutation enhances PyMT-induced mammary tumorigenesis Cortactin as a target for FAK in the regulation of focal adhesion dynamics NSP-CAS Protein Complexes: Emerging Signaling Modules in Cancer A requirement for Nedd9 in luminal progenitor cells prior to mammary tumorigenesis in MMTV-HER2/ErbB2 mice Association of the breast cancer antiestrogen resistance protein 1 (BCAR1) and BCAR3 scaffolding proteins in cell signaling and antiestrogen resistance Pilot study: alteration of deleted in liver cancer1 and phosphorylated focal adhesion kinase Y397 cytoplasmic expression and the prognostic value in advanced epithelial ovarian carcinoma Receptor activator of NF-kB (RANK) expression in primary tumors associates with bone metastasis occurrence in breast cancer patients E4orf1: a novel ligand that improves glucose disposal in cell culture Bi-directional signaling: extracellular matrix and integrin regulation of breast tumor progression Integrins in cancer: biological implications and therapeutic opportunities Differential requirement for focal adhesion kinase signaling in cancer progression in the transgenic adenocarcinoma of mouse prostate model Proline-rich tyrosine kinase 2 (Pyk2) regulates IGF-I-induced cell motility and invasion of urothelial carcinoma cells.p130Cas over-expression impairs mammary branching morphogenesis in response to estrogen and EGF.CXCR1/2 pathways in paclitaxel-induced neuropathic pain Estrogen receptor-alpha promotes breast cancer cell motility and invasion via focal adhesion kinase and N-WASP.Mammary gland-specific ablation of focal adhesion kinase reduces the incidence of p53-mediated mammary tumour formation.p130Cas/Cyclooxygenase-2 axis in the control of mesenchymal plasticity of breast cancer cells.Alpha-mangostin inhibits intracellular fatty acid synthase and induces apoptosis in breast cancer cells.Integrin signaling through FAK in the regulation of mammary stem cells and breast cancer Focal adhesion kinase: a prominent determinant in breast cancer initiation, progression and metastasis Bacterial Autophagy: Offense and Defense at the Host-Pathogen Interface.The insulin-like growth factor receptor I promotes motility and invasion of bladder cancer cells through Akt- and mitogen-activated protein kinase-dependent activation of paxillin.beta1-integrin is dispensable for the induction of ErbB2 mammary tumors but plays a critical role in the metastatic phase of tumor progression Oral delivery of PND-1186 FAK inhibitor decreases tumor growth and spontaneous breast to lung metastasis in pre-clinical models.PND-1186 FAK inhibitor selectively promotes tumor cell apoptosis in three-dimensional environments.FAK deletion promotes p53-mediated induction of p21, DNA-damage responses and radio-resistance in advanced squamous cancer cells.Oncogenes and tumor suppressor genes RAS Interaction with PI3K: More Than Just Another Effector Pathway Lack of fetuin-A (alpha2-HS-glycoprotein) reduces mammary tumor incidence and prolongs tumor latency via the transforming growth factor-beta signaling pathway in a mouse model of breast cancer.Force engages vinculin and promotes tumor progression by enhancing PI3K activation of phosphatidylinositol (3,4,5)-triphosphate.Mammary gland ECM remodeling, stiffness, and mechanosignaling in normal development and tumor progression Deletion of Cd151 reduces mammary tumorigenesis in the MMTV/PyMT mouse model.Nuclear FAK controls chemokine transcription, Tregs, and evasion of anti-tumor immunity.Integrin beta1-focal adhesion kinase signaling directs the proliferation of metastatic cancer cells disseminated in the lungs.FAK is required for c-Met/β-catenin-driven hepatocarcinogenesis.

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P2860

Ras- and PI3K-dependent breast tumorigenesis in mice and humans requires focal adhesion kinase signaling.

http://www.wikidata.org/entity/Q37073729

description

article científic

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article scientifique

@fr

articolo scientifico

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artigo científico

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bilimsel makale

@tr

scientific article published on 19 January 2009

@en

vedecký článok

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vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Ras- and PI3K-dependent breast ...... cal adhesion kinase signaling.

@en

Ras- and PI3K-dependent breast ...... cal adhesion kinase signaling.

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type

label

Ras- and PI3K-dependent breast ...... cal adhesion kinase signaling.

@en

Ras- and PI3K-dependent breast ...... cal adhesion kinase signaling.

@nl

prefLabel

Ras- and PI3K-dependent breast ...... cal adhesion kinase signaling.

@en

Ras- and PI3K-dependent breast ...... cal adhesion kinase signaling.

@nl

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Journal of Clinical Investigation

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Ras- and PI3K-dependent breast ...... ocal adhesion kinase signaling

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Filippo G Giancotti

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Hilary E Beggs

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Louis F Reichardt

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William Gerald

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Yuliya Pylayeva

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P2860

Nuclear FAK promotes cell proliferation and survival through FERM-enhanced p53 degradation

A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes

GATA-3 links tumor differentiation and dissemination in a luminal breast cancer model

Differential regulation of cell motility and invasion by FAK

High resolution genomic analysis of sporadic breast cancer using array-based comparative genomic hybridization

A transforming mutation in the pleckstrin homology domain of AKT1 in cancer

Generalized lacZ expression with the ROSA26 Cre reporter strain

Stem cells, cancer, and cancer stem cells

Tensional homeostasis and the malignant phenotype

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252-266

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scholarly article

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10.1172/JCI37160

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2

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2009-01-19T00:00:00Z

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19147981

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2631302

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