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Insulin in the brain: its pathophysiological implications for States related with central insulin resistance, type 2 diabetes and Alzheimer's diseaseRole of microRNAs in islet beta-cell compensation and failure during diabetesModulation of microRNA Expression in Subjects with Metabolic Syndrome and Decrease of Cholesterol Efflux from Macrophages via microRNA-33-Mediated Attenuation of ATP-Binding Cassette Transporter A1 Expression by StatinsAn intracellular role for ABCG1-mediated cholesterol transport in the regulated secretory pathway of mouse pancreatic beta cells.Cholesterol regulates glucose-stimulated insulin secretion through phosphatidylinositol 4,5-bisphosphate.Impaired β cell function in Chinese newly diagnosed type 2 diabetes mellitus with hyperlipidemia.Carriers of loss-of-function mutations in ABCA1 display pancreatic beta-cell dysfunctionStatins and New-Onset Diabetes Mellitus: LDL Receptor May Provide a Key Link.High density lipoproteins and type 2 diabetes: Emerging concepts in their relationship.A functional ABCA1 gene variant is associated with low HDL-cholesterol levels and shows evidence of positive selection in Native Americans.Metabolism of plasma cholesterol and lipoprotein parameters are related to a higher degree of insulin sensitivity in high HDL-C healthy normal weight subjects.Role for inducible cAMP early repressor in promoting pancreatic beta cell dysfunction evoked by oxidative stress in human and rat islets.Clinical, Biochemical, and Molecular Characterization of Novel Mutations in ABCA1 in Families with Tangier DiseaseIslet cholesterol accumulation due to loss of ABCA1 leads to impaired exocytosis of insulin granules.A prospective study of prepregnancy dietary fat intake and risk of gestational diabetes.ApoA-1 mimetic restores adiponectin expression and insulin sensitivity independent of changes in body weight in female obese mice.Developmental origins of adult diseases.Rosuvastatin and atorvastatin: comparative effects on glucose metabolism in non-diabetic patients with dyslipidaemia.Oxidative stress contributes to abnormal glucose metabolism and insulin sensitivity in two hyperlipidemia modelsABC transporter genes and risk of type 2 diabetes: a study of 40,000 individuals from the general population.Dietary patterns and odds of Type 2 diabetes in Beirut, Lebanon: a case-control study.Dyslipidemia and diabetes: reciprocal impact of impaired lipid metabolism and Beta-cell dysfunction on micro- and macrovascular complications.Roles of cholesterol in vesicle fusion and motion.Association between type of dietary fish and seafood intake and the risk of incident type 2 diabetes: the European prospective investigation of cancer (EPIC)-Norfolk cohort study.Brain insulin dysregulation: implication for neurological and neuropsychiatric disorders.Cholesterol-enriched membrane rafts and insulin secretion.Metabolic fate of glucose and candidate signaling and excess-fuel detoxification pathways in pancreatic β-cells.Lipid signaling and lipotoxicity in metaflammation: indications for metabolic disease pathogenesis and treatment.Aberrant activation of liver X receptors impairs pancreatic beta cell function through upregulation of sterol regulatory element-binding protein 1c in mouse islets and rodent cell lines.Modified high-density lipoprotein modulates aldosterone release through scavenger receptors via extra cellular signal-regulated kinase and Janus kinase-dependent pathways.Loss of both ABCA1 and ABCG1 results in increased disturbances in islet sterol homeostasis, inflammation, and impaired β-cell function.Egg and cholesterol intake and incident type 2 diabetes among French women.Relation of four nontraditional lipid profiles to diabetes in rural Chinese H-type hypertension population.High-density lipoprotein function in regulating insulin secretion: possible relevance to metabolic syndromeDistinct metabolic and vascular effects of dietary triglycerides and cholesterol in atherosclerotic and diabetic mouse models.Cholesterol accumulation and diabetes in pancreatic beta-cell-specific SREBP-2 transgenic mice: a new model for lipotoxicity.Ranking factors involved in diabetes remission after bariatric surgery using machine-learning integrating clinical and genomic biomarkers.Associations of common variants in the SLC16A11, TCF7L2, and ABCA1 genes with pediatric-onset type 2 diabetes and related glycemic traits in families: A case-control and case-parent trio study.Correlation between HDL cholesterol levels and beta-cell function in subjects with various degree of glucose tolerance.Effects of cholesterol on pore formation in lipid bilayers induced by human islet amyloid polypeptide fragments: a coarse-grained molecular dynamics study.
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on February 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Cholesterol in islet dysfunction and type 2 diabetes
@en
Cholesterol in islet dysfunction and type 2 diabetes.
@nl
type
label
Cholesterol in islet dysfunction and type 2 diabetes
@en
Cholesterol in islet dysfunction and type 2 diabetes.
@nl
prefLabel
Cholesterol in islet dysfunction and type 2 diabetes
@en
Cholesterol in islet dysfunction and type 2 diabetes.
@nl
P2860
P356
P1476
Cholesterol in islet dysfunction and type 2 diabetes
@en
P2093
C Bruce Verchere
Liam R Brunham
P2860
P304
P356
10.1172/JCI33296
P407
P577
2008-02-01T00:00:00Z