Cholesterol accumulation and diabetes in pancreatic beta-cell-specific SREBP-2 transgenic mice: a new model for lipotoxicity.
about
Combined lipidomic and proteomic analysis of isolated human islets exposed to palmitate reveals time-dependent changes in insulin secretion and lipid metabolismGlucolipotoxicity of the pancreatic beta cell.Relationship between blood lipid profiles and pancreatic islet β cell function in Chinese men and women with normal glucose tolerance: a cross-sectional studyIslet cholesterol accumulation due to loss of ABCA1 leads to impaired exocytosis of insulin granules.Serum CA19-9 level associated with metabolic control and pancreatic beta cell function in diabetic patients.PGC-1 coactivators in β-cells regulate lipid metabolism and are essential for insulin secretion coupled to fatty acidsThe effect of cholesteryl ester transfer protein on pancreatic beta cell dysfunction in micePdx1 and other factors that regulate pancreatic beta-cell survival.Gluttony, sloth and the metabolic syndrome: a roadmap to lipotoxicity.How does diabetes accelerate Alzheimer disease pathology?The emerging role of HDL in glucose metabolism.Stigmasterol prevents glucolipotoxicity induced defects in glucose-stimulated insulin secretion.Developmental and extrahepatic physiological functions of SREBP pathway genes in mice.Coordinate changes in histone modifications, mRNA levels, and metabolite profiles in clonal INS-1 832/13 β-cells accompany functional adaptations to lipotoxicity.Cholesterol Homeostasis in Isolated Lymphocytes: a Differential Correlation Between Male Control and Chronic Lymphocytic Leukemia SubjectsOveractivation of intestinal SREBP2 in mice increases serum cholesterol.Balsamic Vinegar Improves High Fat-Induced Beta Cell Dysfunction via Beta Cell ABCA1.Suppression of the pancreatic duodenal homeodomain transcription factor-1 (Pdx-1) promoter by sterol regulatory element-binding protein-1c (SREBP-1c).PCSK9-deficient mice exhibit impaired glucose tolerance and pancreatic islet abnormalities.Autophagy protects pancreatic beta cell mass and function in the setting of a high-fat and high-glucose diet.SREBP-regulated lipid metabolism: convergent physiology - divergent pathophysiology.The extending spectrum of NPC1-related human disorders: from Niemann-Pick C1 Disease to obesity.Zinc mediates the SREBP-SCD axis to regulate lipid metabolism in Caenorhabditis elegans.Variable effects of gender and Western diet on lipid and glucose homeostasis in aged PCSK9-deficient C57BL/6 mice CSK9PC57BL/6.
P2860
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P2860
Cholesterol accumulation and diabetes in pancreatic beta-cell-specific SREBP-2 transgenic mice: a new model for lipotoxicity.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Cholesterol accumulation and d ...... a new model for lipotoxicity.
@en
Cholesterol accumulation and d ...... a new model for lipotoxicity.
@nl
type
label
Cholesterol accumulation and d ...... a new model for lipotoxicity.
@en
Cholesterol accumulation and d ...... a new model for lipotoxicity.
@nl
prefLabel
Cholesterol accumulation and d ...... a new model for lipotoxicity.
@en
Cholesterol accumulation and d ...... a new model for lipotoxicity.
@nl
P2093
P2860
P1476
Cholesterol accumulation and d ...... a new model for lipotoxicity.
@en
P2093
Akimitsu Takahashi
Hitoshi Shimano
Kazuto Kobayashi
Mayumi Ishikawa
Nobuhiro Yamada
Noriyuki Inoue
Shigeru Yatoh
Shin Kumadaki
Takashi Matsuzaka
Takashi Yamamoto
P2860
P304
P356
10.1194/JLR.M800238-JLR200
P50
P577
2008-08-05T00:00:00Z