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The Lowe syndrome protein OCRL1 is involved in primary cilia assemblyInteractome mapping of the phosphatidylinositol 3-kinase-mammalian target of rapamycin pathway identifies deformed epidermal autoregulatory factor-1 as a new glycogen synthase kinase-3 interactorEmerging roles for the FSH receptor adapter protein APPL1 and overlap of a putative 14-3-3τ interaction domain with a canonical G-protein interaction siteEpicardial Fat: Physiological, Pathological, and Therapeutic Implications5'-Monophosphate-activated protein kinase (AMPK) improves autophagic activity in diabetes and diabetic complicationsCross-Talk between Adiponectin and IGF-IR in Breast CancerAPPL endosomes are not obligatory endocytic intermediates but act as stable cargo-sorting compartments.Loss-of-Function Mutations in APPL1 in Familial Diabetes MellitusAdiponectin and insulin cross talk: the microvascular connection.Delivery of adiponectin gene to skeletal muscle using ultrasound targeted microbubbles improves insulin sensitivity and whole body glucose homeostasisMultifaceted roles of adiponectin in cancer.Cot/tpl2 participates in the activation of macrophages by adiponectin.Identification of phosphorylation sites within the signaling adaptor APPL1 by mass spectrometry.Full-length adiponectin attenuates insulin signaling and inhibits insulin-stimulated amino Acid transport in human primary trophoblast cellsAdiponectin signaling in the liverAdiponectin-induced ERK and Akt phosphorylation protects against pancreatic beta cell apoptosis and increases insulin gene expression and secretion.The role of adiponectin in cancer: a review of current evidence.Linking adiponectin and autophagy in the regulation of breast cancer metastasis.Adiponectin: Probe of the molecular paradigm associating diabetes and obesity.APPL1 mediates adiponectin-stimulated p38 MAPK activation by scaffolding the TAK1-MKK3-p38 MAPK pathway.Adiponectin is protective against oxidative stress induced cytotoxicity in amyloid-beta neurotoxicityThe adapter protein APPL1 links FSH receptor to inositol 1,4,5-trisphosphate production and is implicated in intracellular Ca(2+) mobilizationA Saccharomyces cerevisiae assay system to investigate ligand/AdipoR1 interactions that lead to cellular signalingAssociation of genetic variation in adaptor protein APPL1/APPL2 loci with non-alcoholic fatty liver diseaseUp-regulation of adiponectin expression in antigravitational soleus muscle in response to unloading followed by reloading, and functional overloading in mice.APPL1 potentiates insulin sensitivity by facilitating the binding of IRS1/2 to the insulin receptor.APPL1 mediates adiponectin-induced LKB1 cytosolic localization through the PP2A-PKCzeta signaling pathwayDietary ω-3 polyunsaturated fatty acids decrease retinal neovascularization by adipose-endoplasmic reticulum stress reduction to increase adiponectin.Adiponectin receptor signalling in the brainAdiponectin: an adipokine with protective features against metabolic syndrome.A novel method to measure glucose uptake and myosin heavy chain isoform expression of single fibers from rat skeletal muscle.Deficiency of APPL1 in mice impairs glucose-stimulated insulin secretion through inhibition of pancreatic beta cell mitochondrial function.Insulin promotes macrophage foam cell formation: potential implications in diabetes-related atherosclerosisAdiponectin Signaling Regulates Lipid Production in Human Sebocytes.Differential Associations between CDH13 Genotypes, Adiponectin Levels, and Circulating Levels of Cellular Adhesive MoleculesGenetic risk factors for decreased bone mineral accretion in children with asthma receiving multiple oral corticosteroid bursts.Inactivation of the Class II PI3K-C2β Potentiates Insulin Signaling and SensitivityDownregulation of adiponectin system in granulosa cells and low levels of HMW adiponectin in PCOS.Exercise training performed simultaneously to a high-fat diet reduces the degree of insulin resistance and improves adipoR1-2/APPL1 protein levels in mice.What is the role of adiponectin in obesity related non-alcoholic fatty liver disease?
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 14 October 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
APPL1: role in adiponectin signaling and beyond
@en
APPL1: role in adiponectin signaling and beyond.
@nl
type
label
APPL1: role in adiponectin signaling and beyond
@en
APPL1: role in adiponectin signaling and beyond.
@nl
prefLabel
APPL1: role in adiponectin signaling and beyond
@en
APPL1: role in adiponectin signaling and beyond.
@nl
P2860
P1476
APPL1: role in adiponectin signaling and beyond
@en
P2093
Lily Q Dong
P2860
P304
P356
10.1152/AJPENDO.90731.2008
P50
P577
2008-10-14T00:00:00Z