Phosphonocarboxylates inhibit the second geranylgeranyl addition by Rab geranylgeranyl transferase. - Wikidata - wikimedia - TriplyDB

Phosphonocarboxylates inhibit the second geranylgeranyl addition by Rab geranylgeranyl transferase.

Phosphonocarboxylates inhibit the second geranylgeranyl addition by Rab geranylgeranyl transferase.

http://www.wikidata.org/entity/Q37119792

about

RAB26 and RAB3D are direct transcriptional targets of MIST1 that regulate exocrine granule maturation Structure-guided development of selective RabGGTase inhibitors Host modulators of H1N1 cytopathogenicity Synthesis and Reactivity Studies of α,α-Difluoromethylphosphinates Oncogenic role of rab escort protein 1 through EGFR and STAT3 pathway Farnesyl pyrophosphate synthase modulators: a patent review (2006 - 2010).The regulation of osteoclast function and bone resorption by small GTPases Prenyltransferase Inhibitors: Treating Human Ailments from Cancer to Parasitic Infections.Metabolically regulated endoplasmic reticulum-associated degradation of 3-hydroxy-3-methylglutaryl-CoA reductase: evidence for requirement of a geranylgeranylated protein.N-Oxide derivatives of 3-(3-pyridyl)-2-phosphonopropanoic acids as potential inhibitors of Rab geranylgeranylation.Zoledronic acid induces apoptosis and S-phase arrest in mesothelioma through inhibiting Rab family proteins and topoisomerase II actions.Triazole-based inhibitors of geranylgeranyltransferase II.Mevalonate kinase deficiency leads to decreased prenylation of Rab GTPases.A serendipitous phosphonocarboxylate complex of boron: when vessel becomes reagent.Protein Lipidation: Occurrence, Mechanisms, Biological Functions, and Enabling Technologies.

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Phosphonocarboxylates inhibit the second geranylgeranyl addition by Rab geranylgeranyl transferase.

http://www.wikidata.org/entity/Q37119792

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 11 December 2008

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Phosphonocarboxylates inhibit ...... ab geranylgeranyl transferase.

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Phosphonocarboxylates inhibit ...... ab geranylgeranyl transferase.

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type

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Phosphonocarboxylates inhibit ...... ab geranylgeranyl transferase.

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Phosphonocarboxylates inhibit ...... ab geranylgeranyl transferase.

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prefLabel

Phosphonocarboxylates inhibit ...... ab geranylgeranyl transferase.

@en

Phosphonocarboxylates inhibit ...... ab geranylgeranyl transferase.

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Journal of Biological Chemistry

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Phosphonocarboxylates inhibit ...... Rab geranylgeranyl transferase

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Adam Taylor

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Boris A Kashemirov

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Charles E McKenna

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Frank H Ebetino

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Fraser P Coxon

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Miguel C Seabra

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Richard Tavaré

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Rudi A Baron

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P2860

Isoprenylcysteine carboxyl methyltransferase deficiency in mice

Rab geranylgeranyl transferase catalyzes the geranylgeranylation of adjacent cysteines in the small GTPases Rab1A, Rab3A, and Rab5A

Structure of mammalian protein geranylgeranyltransferase type-I

Crystal structure of Rab geranylgeranyltransferase at 2.0 A resolution

Reaction path of protein farnesyltransferase at atomic resolution

Structure of Rab escort protein-1 in complex with Rab geranylgeranyltransferase

Thematic review series: lipid posttranslational modifications. Structural biology of protein farnesyltransferase and geranylgeranyltransferase type I

cDNA cloning of component A of Rab geranylgeranyl transferase and demonstration of its role as a Rab escort protein

Rab geranylgeranyl transferase. A multisubunit enzyme that prenylates GTP-binding proteins terminating in Cys-X-Cys or Cys-Cys

Inhibitors of protein geranylgeranyltransferase I and Rab geranylgeranyltransferase identified from a library of allenoate-derived compounds.

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scholarly article

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10.1074/JBC.M806952200

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11

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Michael J. Rogers

Ana C Figueiredo

Katarzyna Błażewska

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2008-12-11T00:00:00Z

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23655041

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19074143

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