MyoD and E-protein heterodimers switch rhabdomyosarcoma cells from an arrested myoblast phase to a differentiated state.
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Mechanisms of impaired differentiation in rhabdomyosarcomaA comparative review of canine and human rhabdomyosarcoma with emphasis on classification and pathogenesisMicroRNAs regulate and provide robustness to the myogenic transcriptional networkp53 suppresses muscle differentiation at the myogenin step in response to genotoxic stressDrosophila and mammalian models uncover a role for the myoblast fusion gene TANC1 in rhabdomyosarcomaGenomic profiling of tumor initiating prostatospheres.Delta-like 1 homolog (dlk1): a marker for rhabdomyosarcomas implicated in skeletal muscle regeneration.DUX4 differentially regulates transcriptomes of human rhabdomyosarcoma and mouse C2C12 cellsHistone methyltransferase KMT1A restrains entry of alveolar rhabdomyosarcoma cells into a myogenic differentiated stateMURC/cavin-4 Is Co-Expressed with Caveolin-3 in Rhabdomyosarcoma Tumors and Its Silencing Prevents Myogenic Differentiation in the Human Embryonal RD Cell Line.CIITA is silenced by epigenetic mechanisms that prevent the recruitment of transactivating factors in rhabdomyosarcoma cells.Histone Deacetylase Inhibitors Antagonize Distinct Pathways to Suppress Tumorigenesis of Embryonal Rhabdomyosarcoma.Genome-wide DNA methylation studies suggest distinct DNA methylation patterns in pediatric embryonal and alveolar rhabdomyosarcomas.Comparison of genome-wide binding of MyoD in normal human myogenic cells and rhabdomyosarcomas identifies regional and local suppression of promyogenic transcription factors.Myogenin recruits the histone chaperone facilitates chromatin transcription (FACT) to promote nucleosome disassembly at muscle-specific genes.p53-Independent, normal stem cell sparing epigenetic differentiation therapy for myeloid and other malignanciesPask integrates hormonal signaling with histone modification via Wdr5 phosphorylation to drive myogenesis.MyoD reprogramming requires Six1 and Six4 homeoproteins: genome-wide cis-regulatory module analysis.Repression of TCF3/E2A contributes to Hodgkin lymphomagenesis.Loss of MEF2D expression inhibits differentiation and contributes to oncogenesis in rhabdomyosarcoma cellsCRISPR screen identifies the NCOR/HDAC3 complex as a major suppressor of differentiation in rhabdomyosarcoma.Myogenic regulatory transcription factors regulate growth in rhabdomyosarcomaMolecular and cellular biology of rhabdomyosarcoma.Caveolins in rhabdomyosarcomaRhabdomyosarcomas: an overview on the experimental animal models.An Examination of the Role of Transcriptional and Posttranscriptional Regulation in Rhabdomyosarcoma.Autoregulatory loop between TGF-β1/miR-411-5p/SPRY4 and MAPK pathway in rhabdomyosarcoma modulates proliferation and differentiation.Glycogen synthase kinase 3β represses MYOGENIN function in alveolar rhabdomyosarcoma.Failure to downregulate the BAF53a subunit of the SWI/SNF chromatin remodeling complex contributes to the differentiation block in rhabdomyosarcoma.TGF-β1 suppression of microRNA-450b-5p expression: a novel mechanism for blocking myogenic differentiation of rhabdomyosarcoma.DNMT3B in vitro knocking-down is able to reverse embryonal rhabdomyosarcoma cell phenotype through inhibition of proliferation and induction of myogenic differentiation.Downregulation of microRNAs miR-1, -206 and -29 stabilizes PAX3 and CCND2 expression in rhabdomyosarcoma.Stuck in a balancing act: histone methyltransferase activity of KMT1A traps alveolar rhabdomyosarcomas in an undifferentiated state.miR-206 integrates multiple components of differentiation pathways to control the transition from growth to differentiation in rhabdomyosarcoma cells.Pax7-FKHR transcriptional activity is enhanced by transcriptionally repressed MyoD.Genome-wide binding of the basic helix-loop-helix myogenic inhibitor musculin has substantial overlap with MyoD: implications for buffering activity.Canadine from Corydalis turtschaninovii Stimulates Myoblast Differentiation and Protects against Myotube Atrophy.Alternative Splicing of Transcription Factors Genes in Muscle Physiology and Pathology.Camptothecin exhibits topoisomerase1-independent KMT1A suppression and myogenic differentiation in alveolar rhabdomyosarcoma cells.Transactivating mutation of theMYOD1gene is a frequent event in adult spindle cell rhabdomyosarcoma
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MyoD and E-protein heterodimers switch rhabdomyosarcoma cells from an arrested myoblast phase to a differentiated state.
description
article científic
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article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
@tr
scientific article published on March 2009
@en
vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
MyoD and E-protein heterodimer ...... ase to a differentiated state.
@en
MyoD and E-protein heterodimer ...... ase to a differentiated state.
@nl
type
label
MyoD and E-protein heterodimer ...... ase to a differentiated state.
@en
MyoD and E-protein heterodimer ...... ase to a differentiated state.
@nl
prefLabel
MyoD and E-protein heterodimer ...... ase to a differentiated state.
@en
MyoD and E-protein heterodimer ...... ase to a differentiated state.
@nl
P2093
P2860
P50
P356
P1433
P1476
MyoD and E-protein heterodimer ...... hase to a differentiated state
@en
P2093
Ashlee E Tyler
Erwin Analau
Stephen J Tapscott
Zhihong Yang
P2860
P304
P356
10.1101/GAD.1765109
P577
2009-03-01T00:00:00Z