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Wild-type p53 is a cell cycle checkpoint determinant following irradiation

Wild-type p53 is a cell cycle checkpoint determinant following irradiation

http://www.wikidata.org/entity/Q37152060

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Attenuation of PTEN increases p21 stability and cytosolic localization in kidney cancer cells: a potential mechanism of apoptosis resistance.Chemotherapeutic sensitization of leptomycin B resistant lung cancer cells by pretreatment with doxorubicin High resolution melting for mutation scanning of TP53 exons 5-8 GADD45 induction of a G2/M cell cycle checkpoint Effects of mutant p53 expression on human 15-lipoxygenase-promoter activity and murine 12/15-lipoxygenase gene expression: evidence that 15-lipoxygenase is a mutator gene The human G2 checkpoint control protein hRAD9 is a nuclear phosphoprotein that forms complexes with hRAD1 and hHUS1 Expression of BRC repeats in breast cancer cells disrupts the BRCA2-Rad51 complex and leads to radiation hypersensitivity and loss of G(2)/M checkpoint control A proinflammatory cytokine inhibits p53 tumor suppressor activity RINT-1, a novel Rad50-interacting protein, participates in radiation-induced G(2)/M checkpoint control An induced fit mechanism regulates p53 DNA binding kinetics to confer sequence specificity Interaction of p53 with the human Rad51 protein Identification of a novel p53 functional domain that is necessary for efficient growth suppression A human homologue of the Schizosaccharomyces pombe rad1+ checkpoint gene encodes an exonuclease Identification of a human homologue of the Schizosaccharomyces pombe rad17+ checkpoint gene Stimulation of p53-mediated transcriptional activation by the p53-binding proteins, 53BP1 and 53BP2 Inhibition of p53 DNA binding by human papillomavirus E6 proteins Correction of chromosomal instability and sensitivity to diverse mutagens by a cloned cDNA of the XRCC3 DNA repair gene Functional association of poly(ADP-ribose) polymerase with DNA polymerase alpha-primase complex: a link between DNA strand break detection and DNA replication Regulation of DNA damage-induced apoptosis by the c-Abl tyrosine kinase Mammalian GADD34, an apoptosis- and DNA damage-inducible gene Reconstitution of a MEC1-independent checkpoint in yeast by expression of a novel human fork head cDNA A human homolog of the Schizosaccharomyces pombe rad9+ checkpoint control gene Carcinogenic potential of benzene and toluene when evaluated using cyclin-dependent kinase activation and p53-DNA binding HRAD1 and MRAD1 encode mammalian homologues of the fission yeast rad1(+) cell cycle checkpoint control gene Control of G1 arrest after DNA damage p53-dependent ceramide response to genotoxic stress Chk2/hCds1 functions as a DNA damage checkpoint in G(1) by stabilizing p53 The gadd and MyD genes define a novel set of mammalian genes encoding acidic proteins that synergistically suppress cell growth Regulation of survival, proliferation, invasion, angiogenesis, and metastasis of tumor cells through modulation of inflammatory pathways by nutraceuticals Cytoplasmic p53 polypeptide is associated with ribosomes An apoptosis-inhibiting gene from a nuclear polyhedrosis virus encoding a polypeptide with Cys/His sequence motifs Analysis of the expression and localisation of a LAP protein, human scribble, in the normal and neoplastic epithelium of uterine cervix p53 regulates a G2 checkpoint through cyclin B1 Regulation of transcription functions of the p53 tumor suppressor by the mdm-2 oncogene Kruppel-like factor 4 mediates p53-dependent G1/S cell cycle arrest in response to DNA damage Genetic cooperation between the Werner syndrome protein and poly(ADP-ribose) polymerase-1 in preventing chromatid breaks, complex chromosomal rearrangements, and cancer in mice Possible attenuation of the G2 DNA damage cell cycle checkpoint in HeLa cells by extremely low frequency (ELF) electromagnetic fields Homeobox genes in mammary gland development and neoplasia Concerted action of Nrf2-ARE pathway, MRN complex, HMGB1 and inflammatory cytokines - implication in modification of radiation damage Inhibition of nutlin-resistant HDM2 mutants by stapled peptides

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Wild-type p53 is a cell cycle checkpoint determinant following irradiation

http://www.wikidata.org/entity/Q37152060

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on August 1992

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Wild-type p53 is a cell cycle checkpoint determinant following irradiation

@en

Wild-type p53 is a cell cycle checkpoint determinant following irradiation.

@nl

type

label

Wild-type p53 is a cell cycle checkpoint determinant following irradiation

@en

Wild-type p53 is a cell cycle checkpoint determinant following irradiation.

@nl

prefLabel

Wild-type p53 is a cell cycle checkpoint determinant following irradiation

@en

Wild-type p53 is a cell cycle checkpoint determinant following irradiation.

@nl

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PNAS.89.16.7491

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Wild-type p53 is a cell cycle checkpoint determinant following irradiation

@en

P2093

B S Plunkett

http://www.w3.org/2001/XMLSchema#string

M B Kastan

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S J Kuerbitz

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W V Walsh

http://www.w3.org/2001/XMLSchema#string

P2860

Molecular cloning, primary structure, and expression of the human growth factor-activatable Na+/H+ antiporter

Checkpoints: controls that ensure the order of cell cycle events

Chromosome 17 deletions and p53 gene mutations in colorectal carcinomas

p53 mutations in human cancers

Suppression of human colorectal carcinoma cell growth by wild-type p53

Participation of p53 protein in the cellular response to DNA damage

p53 functions as a cell cycle control protein in osteosarcomas

The p53 proto-oncogene can act as a suppressor of transformation.

Mechanism by which caffeine potentiates lethality of nitrogen mustard

Radiosensitivity in ataxia-telangiectasia: a new explanation.

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7491-7495

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scholarly article

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10.1073/PNAS.89.16.7491

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16

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89

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1992-08-01T00:00:00Z

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21831549

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1323840

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49736

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