Abrogation of TGF-beta signaling enhances chemokine production and correlates with prognosis in human breast cancer.
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Matrix crosslinking forces tumor progression by enhancing integrin signalingComplexities of TGF-β targeted cancer therapy.Attenuated transforming growth factor beta signaling promotes metastasis in a model of HER2 mammary carcinogenesisStromally derived lysyl oxidase promotes metastasis of transforming growth factor-β-deficient mouse mammary carcinomasCXCR4 drives the metastatic phenotype in breast cancer through induction of CXCR2 and activation of MEK and PI3K pathwaysCCL9 Induced by TGFβ Signaling in Myeloid Cells Enhances Tumor Cell Survival in the Premetastatic Organ.The roles of TGFβ in the tumour microenvironment.TGF-beta biology in mammary development and breast cancer.Transforming growth factor beta (TGF-beta) and inflammation in cancer.Associations between genetic variants in the TGF-β signaling pathway and breast cancer risk among Hispanic and non-Hispanic white women.An integrated genomic approach identifies persistent tumor suppressive effects of transforming growth factor-β in human breast cancerTransforming growth factor beta receptor type III is a tumor promoter in mesenchymal-stem like triple negative breast cancer.TGF-beta and immune cells: an important regulatory axis in the tumor microenvironment and progressionQuantitative analysis of the secretome of TGF-beta signaling-deficient mammary fibroblasts.The role of the microenvironment in mammary gland development and cancer.Roles of tumor suppressors in regulating tumor-associated inflammation.Validation of the prognostic gene portfolio, ClinicoMolecular Triad Classification, using an independent prospective breast cancer cohort and external patient populations.Efficient TGF-β/SMAD signaling in human melanoma cells associated with high c-SKI/SnoN expression.Inflammation-mediated genetic and epigenetic alterations drive cancer development in the neighboring epithelium upon stromal abrogation of TGF-β signaling.Outgrowth of drug-resistant carcinomas expressing markers of tumor aggression after long-term TβRI/II kinase inhibition with LY2109761.Dihydromyricetin induces mouse hepatoma Hepal-6 cell apoptosis via the transforming growth factor-β pathway.The role of cytokines in breast cancer development and progressionBreast cancer at bone metastatic sites: recent discoveries and treatment targets.Side populations from cervical-cancer-derived cell lines have stem-cell-like properties.The colorectal tumor microenvironment: the next decade.PDGFRα and β play critical roles in mediating Foxq1-driven breast cancer stemness and chemoresistance.Inhibiting Cxcr2 disrupts tumor-stromal interactions and improves survival in a mouse model of pancreatic ductal adenocarcinoma.Engineered three-dimensional microfluidic device for interrogating cell-cell interactions in the tumor microenvironment.Chemotherapeutic Targeting of the Transforming Growth Factor-β Pathway in Breast Cancers.TGF-β receptor II loss promotes mammary carcinoma progression by Th17 dependent mechanismsDeletion of TGF-β signaling in myeloid cells enhances their anti-tumorigenic properties.Gene expression in extratumoral microenvironment predicts clinical outcome in breast cancer patients.The complexities of TGF-β action during mammary and squamous cell carcinogenesis.Targeting the TGFβ signalling pathway in disease.Bone morphogenetic protein signaling promotes tumorigenesis in a murine model of high-grade gliomaRole of TGF-β and the tumor microenvironment during mammary tumorigenesisLuminal breast cancer metastasis is dependent on estrogen signaling.Forkhead transcription factor foxq1 promotes epithelial-mesenchymal transition and breast cancer metastasisTargeted gene silencing of CCL2 inhibits triple negative breast cancer progression by blocking cancer stem cell renewal and M2 macrophage recruitment.Deficiency in p53 is required for doxorubicin induced transcriptional activation of NF-кB target genes in human breast cancer
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Abrogation of TGF-beta signaling enhances chemokine production and correlates with prognosis in human breast cancer.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 18 May 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Abrogation of TGF-beta signali ...... gnosis in human breast cancer.
@en
Abrogation of TGF-beta signali ...... gnosis in human breast cancer.
@nl
type
label
Abrogation of TGF-beta signali ...... gnosis in human breast cancer.
@en
Abrogation of TGF-beta signali ...... gnosis in human breast cancer.
@nl
prefLabel
Abrogation of TGF-beta signali ...... gnosis in human breast cancer.
@en
Abrogation of TGF-beta signali ...... gnosis in human breast cancer.
@nl
P2093
P2860
P356
P1476
Abrogation of TGF-beta signali ...... gnosis in human breast cancer.
@en
P2093
Anna Chytil
Christine H Chung
Daniel G Stover
Joel S Parker
Mary Aakre
Nikki Cheng
P2860
P304
P356
10.1172/JCI37480
P407
P577
2009-05-18T00:00:00Z