Minireview: Meeting the demand for insulin: molecular mechanisms of adaptive postnatal beta-cell mass expansion
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RETRACTED: Betatrophin: a hormone that controls pancreatic β cell proliferationExposure to bisphenol-A during pregnancy partially mimics the effects of a high-fat diet altering glucose homeostasis and gene expression in adult male miceNatural history of β-cell adaptation and failure in type 2 diabetesGlucocorticoid-induced suppression of β-cell proliferation is mediated by Mig6Regulation of pancreatic β-cell function and mass dynamics by prostaglandin signaling.Current status of islet cell replacement and regeneration therapy.Early peroxisome proliferator-activated receptor gamma regulated genes involved in expansion of pancreatic beta cell massRelationship between whole-body macronutrient oxidative partitioning and pancreatic insulin secretion/β-cell function in non-diabetic humans.Glucose stimulates human beta cell replication in vivo in islets transplanted into NOD-severe combined immunodeficiency (SCID) mice.Functional role of serotonin in insulin secretion in a diet-induced insulin-resistant state.Alterations of pancreatic islet structure, metabolism and gene expression in diet-induced obese C57BL/6J mice.Skeletal muscle insulin resistance in zebrafish induces alterations in β-cell number and glucose tolerance in an age- and diet-dependent mannerProinsulin misfolding and endoplasmic reticulum stress during the development and progression of diabetes.Free fatty acids block glucose-induced β-cell proliferation in mice by inducing cell cycle inhibitors p16 and p18Mice Deficient in Proglucagon-Derived Peptides Exhibit Glucose Intolerance on a High-Fat Diet but Are Resistant to Obesity.Can CD44 Be a Mediator of Cell Destruction? The Challenge of Type 1 Diabetes.Parathyroid Hormone-Related Peptide (1-36) Enhances Beta Cell Regeneration and Increases Beta Cell Mass in a Mouse Model of Partial PancreatectomyOsteoprotegerin and Denosumab Stimulate Human Beta Cell Proliferation through Inhibition of the Receptor Activator of NF-κB Ligand Pathway.Insulin demand regulates β cell number via the unfolded protein response.Nutrient excess stimulates β-cell neogenesis in zebrafish.MicroRNAs contribute to compensatory β cell expansion during pregnancy and obesity.Pancreatic alpha-cells from female mice undergo morphofunctional changes during compensatory adaptations of the endocrine pancreas to diet-induced obesity.Adaptive changes of human islets to an obesogenic environment in the mouse.Sustained expression of the transcription factor GLIS3 is required for normal beta cell function in adults.FoxO1 Plays an Important Role in Regulating β-Cell Compensation for Insulin Resistance in Male Mice.The role of aging upon β cell turnover.Hyperplasia of pancreatic beta cells and improved glucose tolerance in mice deficient in the FXYD2 subunit of Na,K-ATPase.Phosphatidylinositol-3,4,5-triphosphate and cellular signaling: implications for obesity and diabetes.TGFβ receptor signaling is essential for inflammation-induced but not β-cell workload-induced β-cell proliferationPKCζ Is Essential for Pancreatic β-Cell Replication During Insulin Resistance by Regulating mTOR and Cyclin-D2Trimeprazine increases IRS2 in human islets and promotes pancreatic β cell growth and function in miceTargeted overexpression of CKI-insensitive cyclin-dependent kinase 4 increases functional β-cell number through enhanced self-replication in zebrafishAdaptive β-cell proliferation increases early in high-fat feeding in mice, concurrent with metabolic changes, with induction of islet cyclin D2 expression.Inactivation of specific β cell transcription factors in type 2 diabetes.Sphingosine-1-phosphate Phosphatase 2 Regulates Pancreatic Islet β-Cell Endoplasmic Reticulum Stress and Proliferation.Neurogenin3 activation is not sufficient to direct duct-to-beta cell transdifferentiation in the adult pancreas.The effects of Leptin and Adiponectin on Pdx1, Foxm1, and PPARγ Transcription in Rat Islets of Langerhans.Deletion of β-Arrestin2 in mice limited pancreatic beta-cell expansion under metabolic stress through activation of JNK pathway.High Fat Diet Regulation of β-Cell Proliferation and β-Cell Mass.p85α deficiency protects β-cells from endoplasmic reticulum stress-induced apoptosis.
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Minireview: Meeting the demand for insulin: molecular mechanisms of adaptive postnatal beta-cell mass expansion
description
article científic
@ca
article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 05 February 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Minireview: Meeting the demand ...... natal beta-cell mass expansion
@en
Minireview: Meeting the demand ...... atal beta-cell mass expansion.
@nl
type
label
Minireview: Meeting the demand ...... natal beta-cell mass expansion
@en
Minireview: Meeting the demand ...... atal beta-cell mass expansion.
@nl
prefLabel
Minireview: Meeting the demand ...... natal beta-cell mass expansion
@en
Minireview: Meeting the demand ...... atal beta-cell mass expansion.
@nl
P2860
P356
P1476
Minireview: Meeting the demand ...... natal beta-cell mass expansion
@en
P2093
Doris A Stoffers
Mira M Sachdeva
P2860
P304
P356
10.1210/ME.2008-0400
P577
2009-02-05T00:00:00Z