Peripheral lipopolysaccharide (LPS) challenge promotes microglial hyperactivity in aged mice that is associated with exaggerated induction of both pro-inflammatory IL-1beta and anti-inflammatory IL-10 cytokines.
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Microglial Priming and Alzheimer's Disease: A Possible Role for (Early) Immune Challenges and Epigenetics?Inflammation: A novel target of current therapies for hepatic encephalopathy in liver cirrhosisRole of neuroinflammation in the emotional and cognitive alterations displayed by animal models of obesityAging-related changes in neuroimmune-endocrine function: implications for hippocampal-dependent cognitionImpact of age-related neuroglial cell responses on hippocampal deteriorationNeurological events related to influenza A (H1N1) pdm09Neuropsychiatric comorbidity in obesity: role of inflammatory processesNeurovascular unit dysfunction with blood-brain barrier hyperpermeability contributes to major depressive disorder: a review of clinical and experimental evidenceMicroglial priming and enhanced reactivity to secondary insult in aging, and traumatic CNS injury, and neurodegenerative diseaseNeuroimmune and Neuropathic Responses of Spinal Cord and Dorsal Root Ganglia in Middle AgePyrrolidine Dithiocarbamate Prevents Neuroinflammation and Cognitive Dysfunction after Endotoxemia in Rats.The yin and yang of microgliaBalancing the immune response in the brain: IL-10 and its regulationNeuroinflammation in the normal aging hippocampusMicroglia and memory: modulation by early-life infectionInterleukin-10/Ceftriaxone prevents E. coli-induced delays in sensorimotor task learning and spatial memory in neonatal and adult Sprague-Dawley ratsRe-establishment of anxiety in stress-sensitized mice is caused by monocyte trafficking from the spleen to the brain.Age decreases macrophage IL-10 expression: Implications for functional recovery and tissue repair in spinal cord injuryNeuroinflammation in Parkinson's disease: its role in neuronal death and implications for therapeutic interventionIntracranial electrode implantation produces regional neuroinflammation and memory deficits in rats.Differential sensitivity to endotoxin exposure in young and middle-age miceTLR-4-dependent and -independent mechanisms of fetal brain injury in the setting of preterm birthTGFβ produced by IL-10 redirected astrocytes attenuates microglial activationTargeting Wnt signaling at the neuroimmune interface for dopaminergic neuroprotection/repair in Parkinson's disease.IL-4 signaling drives a unique arginase+/IL-1β+ microglia phenotype and recruits macrophages to the inflammatory CNS: consequences of age-related deficits in IL-4Rα after traumatic spinal cord injury.Microglia activation and anti-inflammatory regulation in Alzheimer's diseaseConsuming a diet supplemented with resveratrol reduced infection-related neuroinflammation and deficits in working memory in aged miceAging sensitizes rapidly isolated hippocampal microglia to LPS ex vivo.Protracted downregulation of CX3CR1 on microglia of aged mice after lipopolysaccharide challengeToll-like receptor 4: innate immune regulator of neuroimmune and neuroendocrine interactions in stress and major depressive disorderAt the extreme end of the psychoneuroimmunological spectrum: delirium as a maladaptive sickness behaviour response.Memory impairments in healthy aging: Role of aging-induced microglial sensitization.Blockade of brain angiotensin II AT1 receptors ameliorates stress, anxiety, brain inflammation and ischemia: Therapeutic implications.Low-level laser therapy regulates microglial function through Src-mediated signaling pathways: implications for neurodegenerative diseasesFractalkine receptor (CX3CR1) deficiency sensitizes mice to the behavioral changes induced by lipopolysaccharideThe NLRP3 inflammasome modulates sleep and NREM sleep delta power induced by spontaneous wakefulness, sleep deprivation and lipopolysaccharide.Differential rescue of spatial memory deficits in aged rats by L-type voltage-dependent calcium channel and ryanodine receptor antagonism.The role of hepatic and splenic macrophages in E. coli-induced memory impairments in aged ratsAngiotensin II AT1 receptor blockade ameliorates brain inflammation.Doxycycline Suppresses Microglial Activation by Inhibiting the p38 MAPK and NF-kB Signaling Pathways.
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Peripheral lipopolysaccharide (LPS) challenge promotes microglial hyperactivity in aged mice that is associated with exaggerated induction of both pro-inflammatory IL-1beta and anti-inflammatory IL-10 cytokines.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 12 September 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Peripheral lipopolysaccharide ...... -inflammatory IL-10 cytokines.
@en
Peripheral lipopolysaccharide
@nl
type
label
Peripheral lipopolysaccharide ...... -inflammatory IL-10 cytokines.
@en
Peripheral lipopolysaccharide
@nl
prefLabel
Peripheral lipopolysaccharide ...... -inflammatory IL-10 cytokines.
@en
Peripheral lipopolysaccharide
@nl
P2093
P2860
P921
P1476
Peripheral lipopolysaccharide ...... -inflammatory IL-10 cytokines.
@en
P2093
Angela M Wynne
Christopher J Henry
Jonathan P Godbout
P2860
P304
P356
10.1016/J.BBI.2008.09.002
P577
2008-09-12T00:00:00Z