Amyotrophic lateral sclerosis-related VAPB P56S mutation differentially affects the function and survival of corticospinal and spinal motor neurons.
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Autophagy and Neurodegeneration: Insights from a Cultured Cell Model of ALSNeurodegenerative diseases in a dish: the promise of iPSC technology in disease modeling and therapeutic discoveryAmyotrophic lateral sclerosis-linked mutant VAPB inclusions do not interfere with protein degradation pathways or intracellular transport in a cultured cell modelMutations in the Matrin 3 gene cause familial amyotrophic lateral sclerosisThe amyotrophic lateral sclerosis 8 protein, VAP, is required for ER protein quality controlProtein Quality Control and the Amyotrophic Lateral Sclerosis/Frontotemporal Dementia ContinuumiPSCs as a major opportunity to understand and cure age-related diseases.Clinical and genetic diversity of SMN1-negative proximal spinal muscular atrophiesA genetic screen identifies Tor as an interactor of VAPB in a Drosophila model of amyotrophic lateral sclerosis.Vapb/Amyotrophic lateral sclerosis 8 knock-in mice display slowly progressive motor behavior defects accompanying ER stress and autophagic response.Rare Variants in Neurodegeneration Associated Genes Revealed by Targeted Panel Sequencing in a German ALS Cohort.Gain-of-function mutations in the ALS8 causative gene VAPB have detrimental effects on neurons and muscles.Neuregulin 1-ErbB module in C-bouton synapses on somatic motor neurons: molecular compartmentation and response to peripheral nerve injury.ER Dysfunction and Protein Folding Stress in ALS.Induced Pluripotent Stem Cells for Disease Modeling and Drug Discovery in Neurodegenerative Diseases.Generation of Cholinergic and Dopaminergic Interneurons from Human Pluripotent Stem Cells as a Relevant Tool for In Vitro Modeling of Neurological Disorders Pathology and Therapy.Neuronal overexpression of human VAPB slows motor impairment and neuromuscular denervation in a mouse model of ALS.Sigma-1 Receptor in Motoneuron Disease.Causative Genes in Amyotrophic Lateral Sclerosis and Protein Degradation Pathways: a Link to Neurodegeneration.ALS-Associated Endoplasmic Reticulum Proteins in Denervated Skeletal Muscle: Implications for Motor Neuron Disease Pathology.Genetic ablation of dynactin p150Glued in postnatal neurons causes preferential degeneration of spinal motor neurons in aged mice.Autophagy as a common pathway in amyotrophic lateral sclerosis.ER Dynamics and Derangement in Neurological Diseases.Nucleocytoplasmic transport defect in a North American patient with ALS8.
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P2860
Amyotrophic lateral sclerosis-related VAPB P56S mutation differentially affects the function and survival of corticospinal and spinal motor neurons.
description
article científic
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article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
@tr
scientific article published on 13 June 2013
@en
vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Amyotrophic lateral sclerosis- ...... inal and spinal motor neurons.
@en
Amyotrophic lateral sclerosis- ...... inal and spinal motor neurons.
@nl
type
label
Amyotrophic lateral sclerosis- ...... inal and spinal motor neurons.
@en
Amyotrophic lateral sclerosis- ...... inal and spinal motor neurons.
@nl
prefLabel
Amyotrophic lateral sclerosis- ...... inal and spinal motor neurons.
@en
Amyotrophic lateral sclerosis- ...... inal and spinal motor neurons.
@nl
P2093
P2860
P356
P1476
Amyotrophic lateral sclerosis- ...... inal and spinal motor neurons.
@en
P2093
Chengsong Xie
Huaibin Cai
Leonardo Aliaga
Michael J O'Donovan
Nikolai Chub
Wan-Jou Yang
P2860
P304
P356
10.1093/HMG/DDT279
P577
2013-06-13T00:00:00Z