Mitochondrial DNA depletion in rat liver induced by fosalvudine tidoxil, a novel nucleoside reverse transcriptase inhibitor prodrug
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The kinetic effects on thymidine kinase 2 by enzyme-bound dTTP may explain the mitochondrial side effects of antiviral thymidine analogsBalancing antiviral potency and host toxicity: identifying a nucleotide inhibitor with an optimal kinetic phenotype for HIV-1 reverse transcriptase.Central role of mitochondria in drug-induced liver injury.
P2860
Mitochondrial DNA depletion in rat liver induced by fosalvudine tidoxil, a novel nucleoside reverse transcriptase inhibitor prodrug
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 11 May 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Mitochondrial DNA depletion in ...... ranscriptase inhibitor prodrug
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Mitochondrial DNA depletion in ...... anscriptase inhibitor prodrug.
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label
Mitochondrial DNA depletion in ...... ranscriptase inhibitor prodrug
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Mitochondrial DNA depletion in ...... anscriptase inhibitor prodrug.
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Mitochondrial DNA depletion in ...... ranscriptase inhibitor prodrug
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Mitochondrial DNA depletion in ...... anscriptase inhibitor prodrug.
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P2093
P2860
P356
P1476
Mitochondrial DNA depletion in ...... ranscriptase inhibitor prodrug
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P2093
Ana C Venhoff
Brigitte Heckl-Ostreicher
Dirk Lebrecht
Frank U Reuss
Nils Venhoff
Roland Wehr
Ulrich A Walker
P2860
P304
P356
10.1128/AAC.00364-09
P407
P577
2009-05-11T00:00:00Z