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Nedd4 family interacting protein 1 (Ndfip1) is required for ubiquitination and nuclear trafficking of BRCA1-associated ATM activator 1 (BRAT1) during the DNA damage responseProtein kinases and phosphatases in the control of cell fateAkt and autophagy cooperate to promote survival of drug-resistant gliomaRegulation of mRNA export by the PI3 kinase/AKT signal transduction pathway.The genetic and neurobiologic compass points toward common signaling dysfunctions in autism spectrum disordersSignaling Interplay between Bone Marrow Adipose Tissue and Multiple Myeloma cellsGenetic and epigenetic heterogeneity of epithelial ovarian cancer and the clinical implications for molecular targeted therapyThe PTEN tumor suppressor gene and its role in lymphoma pathogenesisEmerging Roles for Maf1 beyond the Regulation of RNA Polymerase III ActivityCharacterizing autism spectrum disorders by key biochemical pathways.Targeting Apoptosis and Multiple Signaling Pathways with Icariside II in Cancer CellsDiverse mechanisms of AKT pathway activation in human malignancyCellular prostatic acid phosphatase, a PTEN-functional homologue in prostate epithelia, functions as a prostate-specific tumor suppressorOvarian cancer biomarker discovery based on genomic approachesKilling me softly--future challenges in apoptosis researchPhosphoinositides in the mammalian endo-lysosomal networkTargeting aberrant colon cancer-specific DNA methylation with lipoteichoic acid-deficient Lactobacillus acidophilusA peptide against soluble guanylyl cyclase α1: a new approach to treating prostate cancerPTEN hopping on the cell membrane is regulated via a positively-charged C2 domainRegulation of lipid binding underlies the activation mechanism of class IA PI3-kinasesObesity and colorectal cancer: molecular features of adipose tissueQuestioning the preclinical paradigm: natural, extreme biology as an alternative discovery platformMicroRNA and transcription factor co-regulatory network analysis reveals miR-19 inhibits CYLD in T-cell acute lymphoblastic leukemiaRal GTPases in tumorigenesis: emerging from the shadowsEpithelial cancers in the post-genomic era: should we reconsider our lifestyle?Development of a human breast-cancer derived cell line stably expressing a bioluminescence resonance energy transfer (BRET)-based phosphatidyl inositol-3 phosphate (PIP3) biosensorTargeting AKT1-E17K and the PI3K/AKT Pathway with an Allosteric AKT Inhibitor, ARQ 092PI-103 and Quercetin Attenuate PI3K-AKT Signaling Pathway in T- Cell Lymphoma Exposed to Hydrogen PeroxideComparative transcriptional network modeling of three PPAR-α/γ co-agonists reveals distinct metabolic gene signatures in primary human hepatocytesSHIP2 multiple functions: a balance between a negative control of PtdIns(3,4,5)P₃ level, a positive control of PtdIns(3,4)P₂ production, and intrinsic docking properties.Ras and Rap signaling in synaptic plasticity and mental disorders.PTEN regulation of local and long-range connections in mouse auditory cortex.Disruption of PKB signaling restores polarity to cells lacking tumor suppressor PTEN.Pten deletion causes mTorc1-dependent ectopic neuroblast differentiation without causing uniform migration defects.Dynamic steps in receptor tyrosine kinase mediated activation of class IA phosphoinositide 3-kinases (PI3K) captured by H/D exchange (HDX-MS).MRI reveals the in vivo cellular and vascular response to BEZ235 in ovarian cancer xenografts with different PI3-kinase pathway activity.A non-negative matrix factorization method for detecting modules in heterogeneous omics multi-modal data.EGF signalling and rapamycin-mediated mTOR inhibition in glioblastoma multiforme evaluated by phospho-specific flow cytometry.Cell type specificity of PI3K signaling in Pdk1- and Pten-deficient brainsThe role of the PTEN/PI3K/Akt pathway on prognosis in epithelial ovarian cancer: a meta-analysis
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on January 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
PTEN and the PI3-kinase pathway in cancer
@en
PTEN and the PI3-kinase pathway in cancer.
@nl
type
label
PTEN and the PI3-kinase pathway in cancer
@en
PTEN and the PI3-kinase pathway in cancer.
@nl
prefLabel
PTEN and the PI3-kinase pathway in cancer
@en
PTEN and the PI3-kinase pathway in cancer.
@nl
P2860
P1476
PTEN and the PI3-kinase pathway in cancer
@en
P2093
Nader Chalhoub
Suzanne J Baker
P2860
P304
P356
10.1146/ANNUREV.PATHOL.4.110807.092311
P577
2009-01-01T00:00:00Z