Clinical radiation sensitivity with DNA repair disorders: an overview.
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Use of the γ-H2AX assay to monitor DNA damage and repair in translational cancer researchNucleotide salvage deficiencies, DNA damage and neurodegenerationCancer risks associated with external radiation from diagnostic imaging proceduresATM-dependent MiR-335 targets CtIP and modulates the DNA damage responseComprehensive profiling of radiosensitive human cell lines with DNA damage response assays identifies the neutral comet assay as a potential surrogate for clonogenic survival.Homozygous mutation of MTPAP causes cellular radiosensitivity and persistent DNA double-strand breaks.Individual patient data meta-analysis shows a significant association between the ATM rs1801516 SNP and toxicity after radiotherapy in 5456 breast and prostate cancer patients.Acute radiation dermatitis in breast cancer patients: challenges and solutionsNew challenges in high-energy particle radiobiology.Prostate-targeted radiosensitization via aptamer-shRNA chimeras in human tumor xenografts.Evaluation and management of pulmonary disease in ataxia-telangiectasiaFunctional proteomics analysis to study ATM dependent signaling in response to ionizing radiation.The Molecular Crosstalk between the MET Receptor Tyrosine Kinase and the DNA Damage Response-Biological and Clinical AspectsThe current progress and future prospects of personalized radiogenomic cancer study.Homozygous deficiency of ubiquitin-ligase ring-finger protein RNF168 mimics the radiosensitivity syndrome of ataxia-telangiectasia.Identification of novel radiosensitizers in a high-throughput, cell-based screen for DSB repair inhibitors.Hypersensitivity to chemoradiation in FANCA carrier with cervical carcinoma-A case report and review of the literature.Fanconi anemia and vaginal squamous cell carcinomaInhibition of MEK confers hypersensitivity to X-radiation in the context of BRAF mutation in a model of childhood astrocytomaSarcoma risk after radiation exposure.Two cases with fatal outcome following total lung irradiation for metastatic bone sarcoma.Effects of expression level of DNA repair-related genes involved in the NHEJ pathway on radiation-induced cognitive impairment.Ovarian cancer and DNA repair: DNA ligase IV as a potential key.Molecular targets and mechanisms of radiosensitization using DNA damage response pathways.Analysis of single nucleotide polymorphisms and radiation sensitivity of the lung assessed with an objective radiologic endpoinImplications of genotypic differences in the generation of a urinary metabolomics radiation signature.Genetic predispositions to childhood leukemia.Unsolved mystery: the role of BRCA1 in DNA end-joining.Radiogenomics: using genetics to identify cancer patients at risk for development of adverse effects following radiotherapy.Genomic instability and the selection of treatments for cancer.Strong association between cancer and genomic instability.Genomic analysis of exceptional responders to radiotherapy reveals somatic mutations in ATM.Inherited syndromes.Guidelines for preclinical and early phase clinical assessment of novel radiosensitisersDNA repair: the link between primary immunodeficiency and cancer.Current clinical management of Fanconi anemia.Radiogenomics: the search for genetic predictors of radiotherapy response.UHRF1 confers radioresistance to human breast cancer cells.A small interfering RNA screen of genes involved in DNA repair identifies tumor-specific radiosensitization by POLQ knockdown.Radioprotective effects of manganese-containing superoxide dismutase mimics on ataxia-telangiectasia cells.
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Clinical radiation sensitivity with DNA repair disorders: an overview.
description
article científic
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article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on August 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Clinical radiation sensitivity with DNA repair disorders: an overview.
@en
Clinical radiation sensitivity with DNA repair disorders: an overview.
@nl
type
label
Clinical radiation sensitivity with DNA repair disorders: an overview.
@en
Clinical radiation sensitivity with DNA repair disorders: an overview.
@nl
prefLabel
Clinical radiation sensitivity with DNA repair disorders: an overview.
@en
Clinical radiation sensitivity with DNA repair disorders: an overview.
@nl
P2860
P1476
Clinical radiation sensitivity with DNA repair disorders: an overview.
@en
P2093
Julianne M Pollard
Richard A Gatti
P2860
P304
P356
10.1016/J.IJROBP.2009.02.057
P407
P577
2009-08-01T00:00:00Z