Targeting ROR1 inhibits epithelial-mesenchymal transition and metastasis. - Wikidata - wikimedia - TriplyDB

Targeting ROR1 inhibits epithelial-mesenchymal transition and metastasis.

Targeting ROR1 inhibits epithelial-mesenchymal transition and metastasis.

http://www.wikidata.org/entity/Q37320359

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Anti-Cancer Stem-like Cell Compounds in Clinical Development - An Overview and Critical Appraisal Pre-clinical Specificity and Safety of UC-961, a First-In-Class Monoclonal Antibody Targeting ROR1 ROR1, an embryonic protein with an emerging role in cancer biology Receptor tyrosine kinase gene expression profiles of Ewing sarcomas reveal ROR1 as a potential therapeutic target in metastatic disease.Wnt5a Signaling in Normal and Cancer Stem Cells ROR1 expression as a biomarker for predicting prognosis in patients with colorectal cancer.ROR1 expression correlated with poor clinical outcome in human ovarian cancer RASAL2 down-regulation in ovarian cancer promotes epithelial-mesenchymal transition and metastasis Ovarian cancer stem cells express ROR1, which can be targeted for anti-cancer-stem-cell therapy.Safety of targeting ROR1 in primates with chimeric antigen receptor-modified T cells.ROR1 as a novel therapeutic target for EGFR-mutant non-small-cell lung cancer patients with the EGFR T790M mutation.IGF1R- and ROR1-Specific CAR T Cells as a Potential Therapy for High Risk Sarcomas.Epigenetic Alterations Affecting Transcription Factors and Signaling Pathways in Stromal Cells of Endometriosis miR-27b-3p suppresses cell proliferation through targeting receptor tyrosine kinase like orphan receptor 1 in gastric cancer.Wnt5a induces ROR1/ROR2 heterooligomerization to enhance leukemia chemotaxis and proliferation.Targeting the ROR1 and ROR2 receptors in epithelial ovarian cancer inhibits cell migration and invasion.Synergistic effect of therapeutic stem cells expressing cytosine deaminase and interferon-beta via apoptotic pathway in the metastatic mouse model of breast cancer.3,6-dihydroxyflavone suppresses the epithelial-mesenchymal transition in breast cancer cells by inhibiting the Notch signaling pathway Migration and invasion is inhibited by silencing ROR1 and ROR2 in chemoresistant ovarian cancer.ROR1 is a novel prognostic biomarker in patients with lung adenocarcinoma.ROR1 can interact with TCL1 and enhance leukemogenesis in Eμ-TCL1 transgenic mice.High-level ROR1 associates with accelerated disease progression in chronic lymphocytic leukemia.Hypoxia induces phenotypic plasticity and therapy resistance in melanoma via the tyrosine kinase receptors ROR1 and ROR2.Increased Hemodynamic Load in Early Embryonic Stages Alters Endocardial to Mesenchymal Transition.Design and implementation of adoptive therapy with chimeric antigen receptor-modified T cells.Receptor tyrosine kinase-like orphan receptor 1: a novel target for cancer immunotherapy.Mining Naïve Rabbit Antibody Repertoires by Phage Display for Monoclonal Antibodies of Therapeutic Utility.Therapeutic vaccination based on side population cells transduced by the granulocyte-macrophage colony-stimulating factor gene elicits potent antitumor immunity.ROR1 contributes to melanoma cell growth and migration by regulating N-cadherin expression via the PI3K/Akt pathway.Approaches for targeting cancer stem cells drug resistance.Receptor tyrosine kinases in carcinogenesis.The sesquiterpene α-bisabolol in the adipocyte-cancer desmoplastic crosstalk: does it have an action on epithelial-mesenchymal transition mechanisms?Overcoming Therapeutic Resistance of Bone Sarcomas: Overview of the Molecular Mechanisms and Therapeutic Targets for Bone Sarcoma Stem Cells.Analysis of ROR1 Protein Expression in Human Cancer and Normal Tissues.Wnt signaling in triple-negative breast cancer.The ROR1 pseudokinase diversifies signaling outputs in MET-addicted cancer cells.In-Silico Drug discovery approach targeting receptor tyrosine kinase-like orphan receptor 1 for cancer treatment.Antitumor activity of a newly developed monoclonal antibody against ROR1 in ovarian cancer cells.Structure-based prediction of Wnt binding affinities for Frizzled-type cysteine-rich domains.Targeting ROR1 inhibits the self-renewal and invasive ability of glioblastoma stem cells.

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Targeting ROR1 inhibits epithelial-mesenchymal transition and metastasis.

http://www.wikidata.org/entity/Q37320359

description

article científic

@ca

article scientifique

@fr

articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on June 2013

@en

vedecký článok

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vetenskaplig artikel

@sv

videnskabelig artikel

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vědecký článek

@cs

name

Targeting ROR1 inhibits epithelial-mesenchymal transition and metastasis.

@en

Targeting ROR1 inhibits epithelial-mesenchymal transition and metastasis.

@nl

type

label

Targeting ROR1 inhibits epithelial-mesenchymal transition and metastasis.

@en

Targeting ROR1 inhibits epithelial-mesenchymal transition and metastasis.

@nl

prefLabel

Targeting ROR1 inhibits epithelial-mesenchymal transition and metastasis.

@en

Targeting ROR1 inhibits epithelial-mesenchymal transition and metastasis.

@nl

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0008-5472.CAN-12-3832

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Cancer Research

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Targeting ROR1 inhibits epithelial-mesenchymal transition and metastasis

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George F Widhopf

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Jessie-F Fecteau

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Jianqiang Yu

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Laura Z Rassenti

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Liguang Chen

http://www.w3.org/2001/XMLSchema#string

Suping Zhang

http://www.w3.org/2001/XMLSchema#string

Thomas J Kipps

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P2860

Hallmarks of Cancer: The Next Generation

NKX2-1/TITF1/TTF-1-Induced ROR1 is required to sustain EGFR survival signaling in lung adenocarcinoma

Antisera induced by infusions of autologous Ad-CD154-leukemia B cells identify ROR1 as an oncofetal antigen and receptor for Wnt5a

A novel family of cell surface receptors with tyrosine kinase-like domain

A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes

Latent bone metastasis in breast cancer tied to Src-dependent survival signals

The epithelial-mesenchymal transition generates cells with properties of stem cells

The basics of epithelial-mesenchymal transition

Epithelial-mesenchymal transitions in development and disease

Cadherin-11 is expressed in invasive breast cancer cell lines

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3649-3660

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scholarly article

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10.1158/0008-5472.CAN-12-3832

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12

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2013-06-01T00:00:00Z

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23771907

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3832210

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