BMI1 cooperates with H-RAS to induce an aggressive breast cancer phenotype with brain metastases.
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MicroRNA-194 inhibits epithelial to mesenchymal transition of endometrial cancer cells by targeting oncogene BMI-1Loss of miR-200 inhibition of Suz12 leads to polycomb-mediated repression required for the formation and maintenance of cancer stem cellsBMI1: A Biomarker of Hematologic MalignanciesBrain tumor modeling using the CRISPR/Cas9 system: state of the art and view to the futureA Novel Aspect of Tumorigenesis-BMI1 Functions in Regulating DNA Damage ResponseThe role of cancer stem cells and miRNAs in defining the complexities of brain metastasisGlobal gene profiling of spontaneous hepatocellular carcinoma in B6C3F1 mice: similarities in the molecular landscape with human liver cancerNanoscale obstacle arrays frustrate transport of EphA2-Ephrin-A1 clusters in cancer cell linesProline metabolism supports metastasis formation and could be inhibited to selectively target metastasizing cancer cellsDeletion analysis of BMI1 oncoprotein identifies its negative regulatory domainDeregulation of the EGFR/PI3K/PTEN/Akt/mTORC1 pathway in breast cancer: possibilities for therapeutic intervention.Bmi-1 Regulates Snail Expression and Promotes Metastasis Ability in Head and Neck Squamous Cancer-Derived ALDH1 Positive CellsBmi-1 promotes invasion and metastasis, and its elevated expression is correlated with an advanced stage of breast cancerValidation of Bmi1 as a therapeutic target of hepatocellular carcinoma in mice.Enhancing chemotherapy response with Bmi-1 silencing in ovarian cancerβTrCP regulates BMI1 protein turnover via ubiquitination and degradation.YB-1 transforms human mammary epithelial cells through chromatin remodeling leading to the development of basal-like breast cancerEstrogen receptor α-coupled Bmi1 regulation pathway in breast cancer and its clinical implications.MicroRNA-31 is a transcriptional target of histone deacetylase inhibitors and a regulator of cellular senescenceLoss of giant obscurins from breast epithelium promotes epithelial-to-mesenchymal transition, tumorigenicity and metastasis.BMI1 suffers a degrading experience.GATA3 inhibits lysyl oxidase-mediated metastases of human basal triple-negative breast cancer cells.HSPA12B: a novel facilitator of lung tumor growthDOT1L cooperates with the c-Myc-p300 complex to epigenetically derepress CDH1 transcription factors in breast cancer progressionDevelopment and Preclinical Application of an Immunocompetent Transplant Model of Basal Breast Cancer with Lung, Liver and Brain Metastases.ConteXt of change--X inactivation and disease.BEclear: Batch Effect Detection and Adjustment in DNA Methylation Data.Bmi-1: At the crossroads of physiological and pathological biology.An integrated transcriptional regulatory circuit that reinforces the breast cancer stem cell stateA positive feedback loop regulates the expression of polycomb group protein BMI1 via WNT signaling pathway.Innovative therapeutic strategies in the treatment of brain metastases.A miR-200c/141-BMI1 autoregulatory loop regulates oncogenic activity of BMI1 in cancer cells.Metabotropic glutamate receptor-1 contributes to progression in triple negative breast cancer.The ZEB1 transcription factor acts in a negative feedback loop with miR200 downstream of Ras and Rb1 to regulate Bmi1 expression.Throwing the cancer switch: reciprocal roles of polycomb and trithorax proteinsEpigenetic factors in cancer development: polycomb group proteins.BMI1 as a novel target for drug discovery in cancer.Linkage between Twist1 and Bmi1: molecular mechanism of cancer metastasis/stemness and clinical implications.Cell lineage determinants as regulators of breast cancer metastasis.Dysregulation of BMI1 and microRNA-16 collaborate to enhance an anti-apoptotic potential in the side population of refractory mantle cell lymphoma.
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BMI1 cooperates with H-RAS to induce an aggressive breast cancer phenotype with brain metastases.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 22 June 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
BMI1 cooperates with H-RAS to ...... enotype with brain metastases.
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BMI1 cooperates with H-RAS to ...... enotype with brain metastases.
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type
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BMI1 cooperates with H-RAS to ...... enotype with brain metastases.
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BMI1 cooperates with H-RAS to ...... enotype with brain metastases.
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BMI1 cooperates with H-RAS to ...... enotype with brain metastases.
@en
BMI1 cooperates with H-RAS to ...... enotype with brain metastases.
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BMI1 cooperates with H-RAS to ...... enotype with brain metastases.
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M J Hoenerhoff
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10.1038/ONC.2009.165
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2009-06-22T00:00:00Z