Glucose promotes survival of rat pancreatic beta cells by activating synthesis of proteins which suppress a constitutive apoptotic program.
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Loss of sugar detection by GLUT2 affects glucose homeostasis in micemiR-375 targets 3'-phosphoinositide-dependent protein kinase-1 and regulates glucose-induced biological responses in pancreatic beta-cellsJunB Inhibits ER Stress and Apoptosis in Pancreatic Beta CellsPancreatic beta cells lack a low glucose and O2-inducible mitochondrial protein that augments cell survivalGLP-1 mediates antiapoptotic effect by phosphorylating Bad through a beta-arrestin 1-mediated ERK1/2 activation in pancreatic beta-cellsEGFR Activation Leads to Cell Death Independent of PI3K/AKT/mTOR in an AD293 Cell LineGLIS3, a susceptibility gene for type 1 and type 2 diabetes, modulates pancreatic beta cell apoptosis via regulation of a splice variant of the BH3-only protein BimToll-like receptor 3 and STAT-1 contribute to double-stranded RNA+ interferon-gamma-induced apoptosis in primary pancreatic beta-cellsCytokines tumor necrosis factor-α and interferon-γ induce pancreatic β-cell apoptosis through STAT1-mediated Bim protein activationPeripheral and islet interleukin-17 pathway activation characterizes human autoimmune diabetes and promotes cytokine-mediated β-cell deathControl of insulin mRNA stability in rat pancreatic islets. Regulatory role of a 3'-untranslated region pyrimidine-rich sequenceBlood glucose levels regulate pancreatic beta-cell proliferation during experimentally-induced and spontaneous autoimmune diabetes in mice.Susceptibility of pancreatic beta cells to fatty acids is regulated by LXR/PPARalpha-dependent stearoyl-coenzyme A desaturase.Transgenic overexpression of active calcineurin in beta-cells results in decreased beta-cell mass and hyperglycemia.Activation of distinct P2Y receptor subtypes stimulates insulin secretion in MIN6 mouse pancreatic beta cells.Ectopic expression of E2F1 stimulates beta-cell proliferation and function.IB1 reduces cytokine-induced apoptosis of insulin-secreting cells.A combined "omics" approach identifies N-Myc interactor as a novel cytokine-induced regulator of IRE1 protein and c-Jun N-terminal kinase in pancreatic beta cells.FLIP switches Fas-mediated glucose signaling in human pancreatic beta cells from apoptosis to cell replication.Exposure to the viral by-product dsRNA or Coxsackievirus B5 triggers pancreatic beta cell apoptosis via a Bim / Mcl-1 imbalance.Glucose infusion in mice: a new model to induce beta-cell replication.The transcription factor C/EBP delta has anti-apoptotic and anti-inflammatory roles in pancreatic beta cellsThe CaMK4/CREB/IRS-2 cascade stimulates proliferation and inhibits apoptosis of β-cellsDecreased beta-cell mass in diabetes: significance, mechanisms and therapeutic implications.The Fas pathway is involved in pancreatic beta cell secretory function.Plasticity of the beta cell insulin secretory competence: preparing the pancreatic beta cell for the next meal.Neuroendocrine immuno-ontogeny of the pathogenesis of autoimmune disease in the nonobese diabetic (NOD) mouse.Differential regulation of CHOP-10/GADD153 gene expression by MAPK signaling in pancreatic beta-cells.The dynamic stress-induced "O-GlcNAc-ome" highlights functions for O-GlcNAc in regulating DNA damage/repair and other cellular pathways.A simple matter of life and death-the trials of postnatal Beta-cell mass regulationMicroRNAs miR-23a-3p, miR-23b-3p, and miR-149-5p Regulate the Expression of Proapoptotic BH3-Only Proteins DP5 and PUMA in Human Pancreatic β-Cells.Modeling dynamic changes in type 1 diabetes progression: quantifying beta-cell variation after the appearance of islet-specific autoimmune responses.Regulation of pancreatic beta-cell mass.Peroxynitrite is a major trigger of cardiomyocyte apoptosis in vitro and in vivo.Insulin stimulates primary beta-cell proliferation via Raf-1 kinase.Beta cells in type 2 diabetes - a crucial contribution to pathogenesis.Initiation and execution of lipotoxic ER stress in pancreatic beta-cells.Npas4 is a novel activity-regulated cytoprotective factor in pancreatic β-cells.Ubiquitin D Regulates IRE1α/c-Jun N-terminal Kinase (JNK) Protein-dependent Apoptosis in Pancreatic Beta CellsPTPN2, a candidate gene for type 1 diabetes, modulates interferon-gamma-induced pancreatic beta-cell apoptosis.
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P2860
Glucose promotes survival of rat pancreatic beta cells by activating synthesis of proteins which suppress a constitutive apoptotic program.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on October 1996
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Glucose promotes survival of r ...... onstitutive apoptotic program.
@en
Glucose promotes survival of r ...... onstitutive apoptotic program.
@nl
type
label
Glucose promotes survival of r ...... onstitutive apoptotic program.
@en
Glucose promotes survival of r ...... onstitutive apoptotic program.
@nl
prefLabel
Glucose promotes survival of r ...... onstitutive apoptotic program.
@en
Glucose promotes survival of r ...... onstitutive apoptotic program.
@nl
P2093
P2860
P921
P356
P1476
Glucose promotes survival of r ...... onstitutive apoptotic program.
@en
P2093
Pipeleers D
Van de Casteele M
P2860
P304
P356
10.1172/JCI118950
P407
P577
1996-10-01T00:00:00Z