Prognostic implications of NOTCH1 and FBXW7 mutations in adult acute T-lymphoblastic leukemia.
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Lessons learned from next-generation sequencing in head and neck cancerPrognostification of ALL by CytogeneticsExome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1Cutaneous papillomavirus E6 oncoproteins associate with MAML1 to repress transactivation and NOTCH signalingMoving towards personalised therapy in head and neck squamous cell carcinoma through analysis of next generation sequencing data.Turn It Down a NotchLow expression of T-cell transcription factor BCL11b predicts inferior survival in adult standard risk T-cell acute lymphoblastic leukemia patientsFLT3 mutations in early T-cell precursor ALL characterize a stem cell like leukemia and imply the clinical use of tyrosine kinase inhibitorsBeyond the 2008 World Health Organization classification: the role of the hematopathology laboratory in the diagnosis and management of acute lymphoblastic leukemiaNotch1 mutations are drivers of oral tumorigenesisMutational spectrum of adult T-ALLClinical and molecular characterization of early T-cell precursor leukemia: a high-risk subgroup in adult T-ALL with a high frequency of FLT3 mutationsPrognostic relevance of integrated genetic profiling in adult T-cell acute lymphoblastic leukemia.Receptor tyrosine kinase amplification is predictive of distant metastasis in patients with oral squamous cell carcinoma.Recent developments in the management of T-cell precursor acute lymphoblastic leukemia/lymphoma.Cytogenetic and molecular predictors of outcome in acute lymphocytic leukemia: recent developments.Oral cavity and oropharyngeal squamous cell carcinoma genomics.Defining the genomic landscape of head and neck cancers through next-generation sequencing.The opposing roles of NOTCH signalling in head and neck cancer: a mini review.HPV Infection of the Head and Neck Region and Its Stem Cells.Synergistic Activity with NOTCH Inhibition and Androgen Ablation in ERG-Positive Prostate Cancer Cells.Poor Response to Standard Chemotherapy in Early T-precursor (ETP)-ALL: A Subtype of T-ALL Associated with Unfavourable Outcome: A Brief ReportDecreased expression of FBXW7 is correlated with poor prognosis in patients with esophageal squamous cell carcinoma.Meta-analysis of the clinical characteristics and prognostic relevance of NOTCH1 and FBXW7 mutation in T-cell acute lymphoblastic leukemia.Molecular pathways: context-dependent approaches to Notch targeting as cancer therapy.Mutations of NOTCH1, FBXW7, and prognosis in T-lineage acute lymphoblastic leukemia.The favorable effect of activating NOTCH1 receptor mutations on long-term outcome in T-ALL patients treated on the ALL-BFM 2000 protocol can be separated from FBXW7 loss of function.NOTCH1 and/or FBXW7 mutations predict for initial good prednisone response but not for improved outcome in pediatric T-cell acute lymphoblastic leukemia patients treated on DCOG or COALL protocols.T-cell Acute Lymphoblastic Leukemia Cells Display Activation of Different Survival Pathways.FBXW7 expression affects the response to chemoradiotherapy and overall survival among patients with oral squamous cell carcinoma: A single-center retrospective study.Elevated TRIB2 with NOTCH1 activation in paediatric/adult T-ALL.Fbxw7β resides in the endoplasmic reticulum membrane and protects cells from oxidative stress.
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Prognostic implications of NOTCH1 and FBXW7 mutations in adult acute T-lymphoblastic leukemia.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on October 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Prognostic implications of NOT ...... cute T-lymphoblastic leukemia.
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Prognostic implications of NOT ...... cute T-lymphoblastic leukemia.
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Prognostic implications of NOT ...... cute T-lymphoblastic leukemia.
@en
Prognostic implications of NOT ...... cute T-lymphoblastic leukemia.
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Prognostic implications of NOT ...... cute T-lymphoblastic leukemia.
@en
Prognostic implications of NOT ...... cute T-lymphoblastic leukemia.
@nl
P2093
P2860
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Prognostic implications of NOT ...... cute T-lymphoblastic leukemia.
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Andrea Stroux
Claudia D Baldus
Cornelia Schlee
Dieter Hoelzer
Eckhard Thiel
Julia Thibaut
Max Mossner
Nicola Goekbuget
Stefan Schwartz
Wolf-Karsten Hofmann
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P304
P356
10.3324/HAEMATOL.2008.005272
P577
2009-10-01T00:00:00Z