Regression of basal cell carcinoma by intralesional interferon-alpha treatment is mediated by CD95 (Apo-1/Fas)-CD95 ligand-induced suicide
about
Treatment of advanced, recurrent, resistant to previous treatments basal and squamous cell skin carcinomas with a synergistic formulation of interferons. Open, prospective study.The immunomodulatory role of CD4-positive cytotoxic T-lymphocytes in health and disease.Antiproliferative Properties of Type I and Type II Interferon.Alterations in molecular killing mechanisms: implications in skin disease.Immunotherapy for nonmelanoma skin cancer: does it have a future?'Activation-induced cell death': a special program able to preserve the homeostasis of the skin?Immunoprevention of basal cell carcinomas with recombinant hedgehog-interacting protein.A novel polyamine analog inhibits growth and induces apoptosis in human breast cancer cells.Type I interferons: key players in normal skin and select cutaneous malignancies.Primary HIV-1 infection of human CD4+ T cells passaged into SCID mice leads to selection of chronically infected cells through a massive fas-mediated autocrine suicide of uninfected cells.Epstein-Barr virus RNA confers resistance to interferon-alpha-induced apoptosis in Burkitt's lymphomaGli2 upregulates cFlip and renders basal cell carcinoma cells resistant to death ligand-mediated apoptosis.Fas-ligand gene silencing in basal cell carcinoma tissue with small interfering RNA.IFNalpha induces Fas expression and apoptosis in hedgehog pathway activated BCC cells through inhibiting Ras-Erk signaling.Regulation of CD95 (Apo-1/Fas) ligand and receptor expression in squamous-cell carcinoma by interferon-gamma and cisplatin.Liposome-mediated gene transfer into human basal cell carcinoma.Cytokine profiles in spontaneously regressing basal cell carcinomas.Keratinocytes constitutively express the CD95 ligand molecule on the plasma membrane: an in situ immunoelectron microscopy study on ultracryosections of normal human skin.STING expression and response to treatment with STING ligands in premalignant and malignant disease.Heterogenous susceptibility to CD95-induced apoptosis in melanoma cells correlates with bcl-2 and bcl-x expression and is sensitive to modulation by interferon-gamma.Blockade of the Fas-triggered intracellular signaling pathway in human melanomas is circumvented by cytotoxic lymphocytes.
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P2860
Regression of basal cell carcinoma by intralesional interferon-alpha treatment is mediated by CD95 (Apo-1/Fas)-CD95 ligand-induced suicide
description
article científic
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article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on December 1997
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Regression of basal cell carci ...... s)-CD95 ligand-induced suicide
@en
Regression of basal cell carci ...... treatment is mediated by CD95
@nl
type
label
Regression of basal cell carci ...... s)-CD95 ligand-induced suicide
@en
Regression of basal cell carci ...... treatment is mediated by CD95
@nl
prefLabel
Regression of basal cell carci ...... s)-CD95 ligand-induced suicide
@en
Regression of basal cell carci ...... treatment is mediated by CD95
@nl
P2093
P2860
P356
P1476
Regression of basal cell carci ...... s)-CD95 ligand-induced suicide
@en
P2093
P2860
P304
P356
10.1172/JCI119814
P407
P577
1997-12-01T00:00:00Z