about
Signal Transduction Pathways of EMT Induced by TGF-β, SHH, and WNT and Their CrosstalksCell-to-cell variability in cell death: can systems biology help us make sense of it all?Oscillatory stress stimulation uncovers an Achilles' heel of the yeast MAPK signaling networkMacrophage polarization drives granuloma outcome during Mycobacterium tuberculosis infectionStochastic modeling suggests that noise reduces differentiation efficiency by inducing a heterogeneous drug response in glioma differentiation therapyDigital microfluidic immunocytochemistry in single cellsDynamic Modeling of the Interaction Between Autophagy and Apoptosis in Mammalian Cells.Marketed nonsteroidal anti-inflammatory agents, antihypertensives, and human immunodeficiency virus protease inhibitors: as-yet-unused weapons of the oncologists' arsenal.Intracellular Information Processing through Encoding and Decoding of Dynamic Signaling Features.A signaling visualization toolkit to support rational design of combination therapies and biomarker discovery: SiViT.Laguerre Filter Analysis with Partial Least Square Regression Reveals a Priming Effect of ERK and CREB on c-FOS Induction.Digital signaling decouples activation probability and population heterogeneity.Mathematical Modeling of Therapy-induced Cancer Drug Resistance: Connecting Cancer Mechanisms to Population Survival RatesDichotomy of cellular inhibition by small-molecule inhibitors revealed by single-cell analysis.Combined targeting of BCL-2 and BCR-ABL tyrosine kinase eradicates chronic myeloid leukemia stem cells.Lysine-Specific Demethylase 1 (LSD1) Inhibitor S2101 Induces Autophagy via the AKT/mTOR Pathway in SKOV3 Ovarian Cancer Cells.Schedule-dependent interaction between anticancer treatments.Cell-to-Cell Variation in p53 Dynamics Leads to Fractional Killing.Modeling of signaling crosstalk-mediated drug resistance and its implications on drug combination.System level dynamics of post-translational modifications.Visualizing and manipulating temporal signaling dynamics with fluorescence-based tools.Modeling the T cell immune response: a fascinating challenge.Novel NF-κB inhibitors: a patent review (2011 - 2014).Topology, dynamics, and heterogeneity in immune signaling.JNK Pathway Activation Modulates Acquired Resistance to EGFR/HER2-Targeted Therapies.Multilayered proteomics reveals molecular switches dictating ligand-dependent EGFR trafficking.Weak-binding molecules are not drugs?-toward a systematic strategy for finding effective weak-binding drugs.Two is better than one; toward a rational design of combinatorial therapy.New insights into mammalian signaling pathways using microfluidic pulsatile inputs and mathematical modeling.Cellular Decision Making by Non-Integrative Processing of TLR Inputs.High-Content Quantification of Single-Cell Immune Dynamics.Evidence linking microRNA suppression of essential prosurvival genes with hippocampal cell death after traumatic brain injury.Semi-adaptive response and noise attenuation in bone morphogenetic protein signallingCustomizing the therapeutic response of signaling networks to promote antitumor responses by drug combinations.Quantitative Analysis of Robustness of Dynamic Response and Signal Transfer in Insulin mediated PI3K/AKT Pathway.Anatomy of a negative feedback loop: the case of IκBα.Stimulus-Dependent Inhibitor of Apoptosis Protein Expression Prolongs the Duration of B Cell SignallingDevelopment. Counting the ways to decode dynamic signals.Modeling cytokine regulatory network dynamics driving neuroinflammation in central nervous system disorders.Synthetic biology: Precision timing in a cell.
P2860
Q26752554-B4774AD4-75A9-48C3-A6D6-556ABDBC59CBQ27013063-4E8CC660-01EC-42AB-8843-DB26CEC1DE9FQ27331443-706333F4-72AA-4C3A-9F0B-8B4FC541B6F5Q28652447-E5315AD2-EB0E-428B-9310-C5AE3ADD6DE8Q28830465-4B700E7A-D6E2-4BD6-9BC9-E842FC9DAF4CQ30656747-6796EBAC-4289-48A8-8247-16BB2F94813EQ34487539-DD9B1DC1-E2E3-4035-89D0-53AEF0C356F8Q35653603-03A1C176-AE09-4893-B8EC-9F5A09BD96F1Q35817151-972E7C5F-5E44-4624-A878-FE6071A60E1CQ36052565-5E4C2E46-53F0-4248-A834-AAD2D40BB34FQ36101566-6BFD90FA-ACB9-40A5-89FA-3E1914B83CCDQ36169804-8BCE6EF8-1BEF-49C8-B16B-80C018065F03Q36634818-3375F8B0-A47B-4B53-8958-C98E268A8C43Q37324081-BF04726F-96E1-4E6A-8C58-9AC11EB5FB14Q37416797-7E11C2D6-504C-4FFE-8F49-1769F316E17BQ37481676-B9BC25B9-ACAC-4851-808B-BB22AABC2A5EQ37566678-7D48C448-D567-43B1-9053-CC16B7659AC8Q37566689-512E3E09-6DB3-4406-841C-DBB49F0361F0Q37665545-B8E6237A-08FE-4C9E-90CA-6D81A1FDCF0EQ38179840-BDE0F56C-97C0-4C0E-9348-1C7A3B3C58E0Q38201425-90BC7C0E-8C3A-4241-A451-CB79DF5E864EQ38243170-989BE169-975B-4AB8-B05D-FD408D491FD4Q38305549-123829A8-F968-4789-A995-D0541701FA4EQ38503829-1443FDD2-6140-46FA-8052-ACE6BC0F781EQ38756230-F66D647A-C813-40E0-A4FD-EAF8362AF6CDQ38773802-F0F618D5-F01C-4160-BEED-9F26D692EEF7Q38897226-544E8339-8C1F-4293-825E-D54AFA432BCFQ38926952-1B77BC36-1E0F-48BA-8057-84F4E006EE23Q39014977-2466110D-235B-416A-8D71-F38267D014BEQ40263359-A43A64EA-7B78-40BD-B964-BD726921870CQ40309362-12DAEBCB-D40A-4A0D-91AC-910F5F4F54E3Q41158909-01A2CC21-A5D5-4A72-980E-8CB1C7997160Q41510444-46C6E1EE-1ABF-47BA-8C58-2FA3E95165BFQ41915916-76A9EBFE-2D5F-40AD-940B-5FC5712C2B1FQ42282068-6855FBC1-C770-43BC-BBF0-E2F874601B03Q42594640-7BC4F3C8-7EB1-4822-9632-B98941541A7AQ42736409-5F497814-421F-43A5-AD1E-6B42D7C3DDE3Q44221924-1A48CCC8-4B28-4893-9612-A40E52C26044Q45068368-86EF4211-268E-4AB4-8BBD-E42174838158Q46138224-17872825-0BD8-40F7-BB77-69506FF28C0C
P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on October 2013
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
The dynamics of signaling as a pharmacological target.
@en
The dynamics of signaling as a pharmacological target.
@nl
type
label
The dynamics of signaling as a pharmacological target.
@en
The dynamics of signaling as a pharmacological target.
@nl
prefLabel
The dynamics of signaling as a pharmacological target.
@en
The dynamics of signaling as a pharmacological target.
@nl
P2093
P2860
P1433
P1476
The dynamics of signaling as a pharmacological target.
@en
P2093
Alexander Hoffmann
Derren Barken
Marcelo Behar
Shannon L Werner
P2860
P304
P356
10.1016/J.CELL.2013.09.018
P407
P577
2013-10-01T00:00:00Z