Identification and characterization of the NMYC gene product in human neuroblastoma cells by monoclonal antibodies with defined specificities.
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HuD, a neuronal-specific RNA-binding protein, is a putative regulator of N-myc pre-mRNA processing/stability in malignant human neuroblastsThe human non-muscle alpha-actinin protein encoded by the ACTN4 gene suppresses tumorigenicity of human neuroblastoma cellsMyc protein is stabilized by suppression of a novel E3 ligase complex in cancer cellsThe human L-myc gene is expressed as two forms of protein in small cell lung carcinoma cell lines: detection by monoclonal antibodies specific to two myc homology box sequencesAlternative processing of RNA transcribed from NMYCThe human L-myc gene encodes multiple nuclear phosphoproteins from alternatively processed mRNAsN-myc gene product expression in neuroblastoma.Structure and expression of the murine L-myc gene.Characteristics of stem cells from human neuroblastoma cell lines and in tumorsMicroRNAs define distinct human neuroblastoma cell phenotypes and regulate their differentiation and tumorigenicityThe c-MYC oncoprotein, the NAMPT enzyme, the SIRT1-inhibitor DBC1, and the SIRT1 deacetylase form a positive feedback loop.A distinct gene expression signature characterizes human neuroblastoma cancer stem cells.Neuroblastoma and other childhood neural tumors: a review.Episome-generated N-myc antisense RNA restricts the differentiation potential of primitive neuroectodermal cell linesMYCN promotes the expansion of Phox2B-positive neuronal progenitors to drive neuroblastoma developmentHsp90 inhibition increases p53 expression and destabilizes MYCN and MYC in neuroblastoma.Biological effects of induced MYCN hyper-expression in MYCN-amplified neuroblastomas.Destabilization of MYC/MYCN by the mitochondrial inhibitors, metaiodobenzylguanidine, metformin and phenformin.S(+)-ibuprofen destabilizes MYC/MYCN and AKT, increases p53 expression, and induces unfolded protein response and favorable phenotype in neuroblastoma cell lines.The MYCN Protein in Health and Disease.Nuclear colocalization of cellular and viral myc proteins with HSP70 in myc-overexpressing cells.Two N-myc polypeptides with distinct amino termini encoded by the second and third exons of the geneSubnuclear localization and antitransforming activity of N-myc:beta-galactosidase fusion proteinsAugmented expression of MYC and/or MYCN protein defines highly aggressive MYC-driven neuroblastoma: a Children's Oncology Group study.Binding of a 40-kDa protein to the N-myc 3'-untranslated region correlates with enhanced N-myc expression in human neuroblastoma.The N-myc proto-oncogene and IGF-II growth factor mRNAs are expressed by distinct cells in human fetal kidney and brain.Exploitation of chick embryo environments to reprogram MYCN-amplified neuroblastoma cells to a benign phenotype, lacking detectable MYCN expression.Rapid and transient decrease of N-myc expression in retinoic acid-induced differentiation of OTF9 teratocarcinoma stem cells.N-myc gene expression and oncoprotein characterisation in medulloblastomap53 cellular localization and function in neuroblastoma: evidence for defective G(1) arrest despite WAF1 induction in MYCN-amplified cells.MYCN-mediated regulation of the MRP1 promoter in human neuroblastoma.MYC-family protein overexpression and prominent nucleolar formation represent prognostic indicators and potential therapeutic targets for aggressive high-MKI neuroblastomas: a report from the children’s oncology group.
P2860
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P2860
Identification and characterization of the NMYC gene product in human neuroblastoma cells by monoclonal antibodies with defined specificities.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
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scientific article published on August 1986
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
@da
vědecký článek
@cs
name
Identification and characteriz ...... es with defined specificities.
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Identification and characteriz ...... es with defined specificities.
@nl
type
label
Identification and characteriz ...... es with defined specificities.
@en
Identification and characteriz ...... es with defined specificities.
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prefLabel
Identification and characteriz ...... es with defined specificities.
@en
Identification and characteriz ...... es with defined specificities.
@nl
P2093
P2860
P356
P1476
Identification and characteriz ...... es with defined specificities.
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P2093
J Bukovsky
R H Kennett
P2860
P304
P356
10.1073/PNAS.83.16.5929
P407
P577
1986-08-01T00:00:00Z