Mitochondrial function, morphology, and axonal transport in amyotrophic lateral sclerosis.
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Parkinson's disease-associated kinase PINK1 regulates Miro protein level and axonal transport of mitochondriaEffects of ALS-related SOD1 mutants on dynein- and KIF5-mediated retrograde and anterograde axonal transportA comprehensive review of amyotrophic lateral sclerosisMicroglia centered pathogenesis in ALS: insights in cell interconnectivityLoad-induced enhancement of Dynein force production by LIS1-NudE in vivo and in vitroThe complex molecular biology of amyotrophic lateral sclerosis (ALS)Dynamin-related protein 1 and mitochondrial fragmentation in neurodegenerative diseasesMitochondrial dysfunction in neurodegenerative diseasesExploring new pathways of neurodegeneration in ALS: the role of mitochondria quality controlDeregulated expression of cytoskeleton related genes in the spinal cord and sciatic nerve of presymptomatic SOD1(G93A) Amyotrophic Lateral Sclerosis mouse model.Role of mitochondria in mutant SOD1 linked amyotrophic lateral sclerosisALS-linked mutant SOD1 damages mitochondria by promoting conformational changes in Bcl-2.Oxidative stress, mitochondrial damage and neurodegenerative diseasesMitochondrial dysfunction and intracellular calcium dysregulation in ALSTherapeutic prospects for mitochondrial disease.Mechanisms, models and biomarkers in amyotrophic lateral sclerosisPersistent inward currents in spinal motoneurons: important for normal function but potentially harmful after spinal cord injury and in amyotrophic lateral sclerosis.SOD1 targeted to the mitochondrial intermembrane space prevents motor neuropathy in the Sod1 knockout mouse.TDP-43-based animal models of neurodegeneration: new insights into ALS pathology and pathophysiology.In vivo pathogenic role of mutant SOD1 localized in the mitochondrial intermembrane spaceEndolysosomal Deficits Augment Mitochondria Pathology in Spinal Motor Neurons of Asymptomatic fALS Mice.Cargo distributions differentiate pathological axonal transport impairments.Mitochondrial dynamics and bioenergetic dysfunction is associated with synaptic alterations in mutant SOD1 motor neurons.Reverse engineering human neurodegenerative disease using pluripotent stem cell technology.PATHOLOGIES OF AXONAL TRANSPORT IN NEURODEGENERATIVE DISEASESA novel phenotype for the dynein heavy chain mutation Loa: altered dendritic morphology, organelle density, and reduced numbers of trigeminal motoneurons.Characterization of early pathogenesis in the SOD1(G93A) mouse model of ALS: part II, results and discussionMutant SOD1 in neuronal mitochondria causes toxicity and mitochondrial dynamics abnormalities.Mitochondrial dysfunction in amyotrophic lateral sclerosis.Mitochondrial trafficking and anchoring in neurons: New insight and implications.ALS Pathogenesis and Therapeutic Approaches: The Role of Mesenchymal Stem Cells and Extracellular VesiclesDysregulation of axonal transport and motorneuron diseases.SOD1 and mitochondria in ALS: a dangerous liaison.Disruption of axonal transport in motor neuron diseases.New Insights on the Mechanisms of Disease Course Variability in ALS from Mutant SOD1 Mouse Models.Mutant SOD1G93A triggers mitochondrial fragmentation in spinal cord motor neurons: neuroprotection by SIRT3 and PGC-1α.Selective mitochondrial Ca2+ uptake deficit in disease endstage vulnerable motoneurons of the SOD1G93A mouse model of amyotrophic lateral sclerosis.Mutant SOD1 and mitochondrial damage alter expression and splicing of genes controlling neuritogenesis in models of neurodegeneration.A mutation in Drosophila Aldolase causes temperature-sensitive paralysis, shortened lifespan, and neurodegeneration.Role of Neuroinflammation in Amyotrophic Lateral Sclerosis: Cellular Mechanisms and Therapeutic Implications.
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Mitochondrial function, morphology, and axonal transport in amyotrophic lateral sclerosis.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on July 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Mitochondrial function, morpho ...... amyotrophic lateral sclerosis.
@en
Mitochondrial function, morpho ...... amyotrophic lateral sclerosis.
@nl
type
label
Mitochondrial function, morpho ...... amyotrophic lateral sclerosis.
@en
Mitochondrial function, morpho ...... amyotrophic lateral sclerosis.
@nl
prefLabel
Mitochondrial function, morpho ...... amyotrophic lateral sclerosis.
@en
Mitochondrial function, morpho ...... amyotrophic lateral sclerosis.
@nl
P2860
P356
P1476
Mitochondrial function, morpho ...... amyotrophic lateral sclerosis.
@en
P2093
Giovanni Manfredi
Jordi Magrané
P2860
P304
P356
10.1089/ARS.2009.2604
P577
2009-07-01T00:00:00Z