Accelerated autoxidation and heme loss due to instability of sickle hemoglobin. - Wikidata - wikimedia - TriplyDB

Accelerated autoxidation and heme loss due to instability of sickle hemoglobin.

Accelerated autoxidation and heme loss due to instability of sickle hemoglobin.

http://www.wikidata.org/entity/Q37481142

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The multiple functions of hemoglobin Immunoregulation in human malaria: the challenge of understanding asymptomatic infection Hemopexin and haptoglobin: allies against heme toxicity from hemoglobin not contenders Sickle erythrocytes target cytotoxics to hypoxic tumor microvessels and potentiate a tumoricidal response Red blood cells induce hypoxic lung inflammation Sickle Cells Abolish Melanoma Tumorigenesis in Hemoglobin SS Knockin Mice and Augment the Tumoricidal Effect of Oncolytic Virus In Vivo Red Blood Cell Function and Dysfunction: Redox Regulation, Nitric Oxide Metabolism, Anemia.Glutathione synthesis and turnover in the human erythrocyte: alignment of a model based on detailed enzyme kinetics with experimental data.Non-heme protein in the giant extracellular hemoglobin of the earthworm Lumbricus terrestris.MP4CO, a pegylated hemoglobin saturated with carbon monoxide, is a modulator of HO-1, inflammation, and vaso-occlusion in transgenic sickle mice.Reconstructing sickle cell disease: a data-based analysis of the "hyperhemolysis paradigm" for pulmonary hypertension from the perspective of evidence-based medicine.A systems biology consideration of the vasculopathy of sickle cell anemia: the need for multi-modality chemo-prophylaxsis.Hydroxyurea-induced expression of glutathione peroxidase 1 in red blood cells of individuals with sickle cell anemia Free heme and the polymerization of sickle cell hemoglobin Sickle hemoglobin instability: a mechanism for malarial protection.Heme oxygenase-1 is a modulator of inflammation and vaso-occlusion in transgenic sickle mice.Pulmonary complications of sickle cell anemia. A need for increased recognition, treatment, and research.Cation modulation of hemoglobin interaction with sodium n-dodecyl sulfate (SDS). III: Calcium interaction with R- and mixed spin states of hemoglobin S at pH 5.0: the musical chair paradox.The proteome of sickle cell disease: insights from exploratory proteomic profiling.The functional nitrite reductase activity of the heme-globins.Haptoglobin attenuates hemoglobin-induced heme oxygenase-1 in renal proximal tubule cells and kidneys of a mouse model of sickle cell disease.Can gas replace protein function? CO abrogates the oxidative toxicity of myoglobin Sickle erythrocytes, after sickling, regulate the expression of the endothelin-1 gene and protein in human endothelial cells in culture.Circulating cell membrane microparticles transfer heme to endothelial cells and trigger vasoocclusions in sickle cell disease.A posttranslational modification of beta-actin contributes to the slow dissociation of the spectrin-protein 4.1-actin complex of irreversibly sickled cells.Sickle Cell Hemoglobin in the Ferryl State Promotes βCys-93 Oxidation and Mitochondrial Dysfunction in Epithelial Lung Cells (E10)Erythrocyte glutamine depletion, altered redox environment, and pulmonary hypertension in sickle cell disease.Comment on "The influence of hydroxyurea on oxidative stress in sickle cell anemia"Sickle hemoglobin disturbs normal coupling among erythrocyte O2 content, glycolysis, and antioxidant capacity.Oxidative instability of hemoglobin E (β26 Glu→Lys) is increased in the presence of free α subunits and reversed by α-hemoglobin stabilizing protein (AHSP): Relevance to HbE/β-thalassemia.Sickle cell disease: role of reactive oxygen and nitrogen metabolites.In vivo reduction of cell-free methemoglobin to oxyhemoglobin results in vasoconstriction in canines.Differential heme release from various hemoglobin redox states and the upregulation of cellular heme oxygenase-1 Endothelin-1 receptor antagonists regulate cell surface-associated protein disulfide isomerase in sickle cell disease.Extracellular hemin crisis triggers acute chest syndrome in sickle mice Basal cell adhesion molecule/lutheran protein. The receptor critical for sickle cell adhesion to laminin.Heme triggers TLR4 signaling leading to endothelial cell activation and vaso-occlusion in murine sickle cell disease.Altered phosphorylation of cytoskeleton proteins in sickle red blood cells: the role of protein kinase C, Rac GTPases, and reactive oxygen species.Hemoglobin-Based Blood Substitutes and the Treatment of Sickle Cell Disease: More Harm than Help?Oxidative stress in sickle cell disease; pathophysiology and potential implications for disease management.

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Accelerated autoxidation and heme loss due to instability of sickle hemoglobin.

http://www.wikidata.org/entity/Q37481142

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on January 1988

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

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vědecký článek

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name

Accelerated autoxidation and heme loss due to instability of sickle hemoglobin.

@en

Accelerated autoxidation and heme loss due to instability of sickle hemoglobin.

@nl

type

label

Accelerated autoxidation and heme loss due to instability of sickle hemoglobin.

@en

Accelerated autoxidation and heme loss due to instability of sickle hemoglobin.

@nl

prefLabel

Accelerated autoxidation and heme loss due to instability of sickle hemoglobin.

@en

Accelerated autoxidation and heme loss due to instability of sickle hemoglobin.

@nl

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Proceedings of the National Academy of Sciences of the United States of America

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Accelerated autoxidation and heme loss due to instability of sickle hemoglobin.

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B E Hedlund

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J W Eaton

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R P Hebbel

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W T Morgan

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P2860

Haptoglobin: a natural bacteriostat

Spontaneous oxygen radical generation by sickle erythrocytes.

Quantitative studies of ferritinlike iron in erythrocytes of thalassemia, sickle-cell anemia, and hemoglobin Hammersmith with Mössbauer spectroscopy.

Abnormal precipitation of oxyhemoglobin S by mechanical shaking.

Domain structure of rabbit hemopexin. Isolation and characterization of a heme-binding glycopeptide.

Inhibition by superoxide dismutase of methemoglobin formation from oxyhemoglobin.

Denaturation of the normal and abnormal hemoglobin molecule.

Red cell membrane abnormalities in sickle cell anemia.

Denatured hemoglobin in sickle erythrocytes.

The use of wheat-germ lectin-Sepharose for the purification of human haemopexin.

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237-241

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scholarly article

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10.1073/PNAS.85.1.237

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1

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85

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1988-01-01T00:00:00Z

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19734756

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3422420

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279519

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