Localization of human factor FVIII inhibitor epitopes to two polypeptide fragments.
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Epitope mapping of human factor VIII inhibitor antibodies by deletion analysis of factor VIII fragments expressed in Escherichia coli.Characterization of a monoclonal anti-idiotype antibody to human anti-factor VIII antibodiesInhibition of human factor VIIIa by anti-A2 subunit antibodies.New-generation recombinant factor concentrates: bridge to gene therapy.Localization of the binding regions of a murine monoclonal anti-factor VIII antibody and a human anti-factor VIII alloantibody, both of which inhibit factor VIII procoagulant activity, to amino acid residues threonine351-serine365 of the factor VIIIMolecular basis of factor VIII inhibition by human antibodies. Antibodies that bind to the factor VIII light chain prevent the interaction of factor VIII with phospholipid.The concept of idiotypic vaccination against factor VIII inhibitors in haemophilia A.Pathophysiology of inhibitors to factor VIII in patients with haemophilia A.Kappa/lambda immunoglobulin distribution in Graves' thyroid-stimulating antibodies. Simultaneous analysis of C lambda gene polymorphisms.The important role of von Willebrand factor in platelet-derived FVIII gene therapy for murine hemophilia A in the presence of inhibitory antibodies.Successful Long Term Eradication of Factor VIII Inhibitor in Patients with Acquired Haemophilia A in Saudi Arabia.Basic aspects of inhibitors to factors VIII and IX and the influence of non-genetic risk factors.Characterization of anti-factor VIII antibody in a patient with acquired hemophilia A.Molecular characterization of mild-to-moderate hemophilia A: detection of the mutation in 25 of 29 patients by denaturing gradient gel electrophoresis.Acquired hemophilia A: a frequently overlooked autoimmune hemorrhagic disorder.Factor VIII inhibitors in hemophilia A: rationale and latest evidenceProduction of recombinant coagulation factors: Are humans the best host cells?Acquired haemophilia and its management.Inhibition of human coagulation factor VIII by monoclonal antibodies. Mapping of functional epitopes with the use of recombinant factor VIII fragments.Acquired haemophilia - a study of ten cases.Immune tolerance in a haemophilia A patient with high inhibitor using locally prepared lyophilized cryoprecipitate.Variation in inhibitor reactivity in acquired haemophilia A with different concentrates.Common inhibitory effects of human anti-C2 domain inhibitor alloantibodies on factor VIII binding to von Willebrand factor.Antibodies to factor VIII in plasma of patients with hemophilia A and normal subjects.Reactivity profile of anti-factor VIII antibodies with designed synthetic peptides mimicking epitopes of the C2 and a1 domains.Influence of von Willebrand factor on the reactivity of human factor VIII inhibitors with factor VIII.The IgG autoimmune response in postpartum acquired hemophilia A targets mainly the A1a1 domain of FVIII.Factor VIII/von Willebrand factor. Structure and function.Anti-idiotypes to factor VIII antibodies and their possible role in the pathogenesis and treatment of factor VIII inhibitors.A recurrent missense mutation (Arg----Gln) and a partial deletion in factor VIII gene causing severe haemophilia A.Analysis of the human factor VIII A2 inhibitor epitope by alanine scanning mutagenesis.Detection and IgG subclass analysis of antibodies to factor VIII in multitransfused haemophiliacs and healthy individuals.Variation in factor VIII inhibitor reactivity with different commercial factor VIII preparations.Disarticulation of a knee joint in a haemophiliac with high inhibitor titre.A new approach to immunologic identification of factor VIII antibodies.Radioimmunoassay for quantitative measurement of factor VIII-heavy chain.Molecular Characterization of the Immune Response to Factor VIII
P2860
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P2860
Localization of human factor FVIII inhibitor epitopes to two polypeptide fragments.
description
1985 nî lūn-bûn
@nan
1985年の論文
@ja
1985年学术文章
@wuu
1985年学术文章
@zh-cn
1985年学术文章
@zh-hans
1985年学术文章
@zh-my
1985年学术文章
@zh-sg
1985年學術文章
@yue
1985年學術文章
@zh
1985年學術文章
@zh-hant
name
Localization of human factor FVIII inhibitor epitopes to two polypeptide fragments.
@en
Localization of human factor FVIII inhibitor epitopes to two polypeptide fragments.
@nl
type
label
Localization of human factor FVIII inhibitor epitopes to two polypeptide fragments.
@en
Localization of human factor FVIII inhibitor epitopes to two polypeptide fragments.
@nl
prefLabel
Localization of human factor FVIII inhibitor epitopes to two polypeptide fragments.
@en
Localization of human factor FVIII inhibitor epitopes to two polypeptide fragments.
@nl
P2093
P2860
P356
P1476
Localization of human factor FVIII inhibitor epitopes to two polypeptide fragments.
@en
P2093
C A Fulcher
C K Kasper
J R Roberts
S de Graaf Mahoney
T S Zimmerman
P2860
P304
P356
10.1073/PNAS.82.22.7728
P407
P577
1985-11-01T00:00:00Z