Transforming growth factor beta-induced cell cycle arrest of human hematopoietic cells requires p57KIP2 up-regulation.
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Targeted inhibition of p57 and p15 blocks transforming growth factor beta-inhibited proliferation of primary cultured human limbal epithelial cellsmyc maintains embryonic stem cell pluripotency and self-renewalCutting the brakes on hematopoietic regeneration by blocking TGFβ to limit chemotherapy-induced myelosuppressionVery small embryonic-like cells: biology and function of these potential endogenous pluripotent stem cells in adult tissuesTGFbeta in CancerNUP98 dysregulation in myeloid leukemogenesisHematopoietic stem cell: self-renewal versus differentiationEmbryonic hematopoiesis in vertebrate somites gives rise to definitive hematopoietic stem cellsA road map toward defining the role of Smad signaling in hematopoietic stem cells.CDKN1C/p57kip2 is a candidate tumor suppressor gene in human breast cancer.Nuclear translocation of Skp2 facilitates its destruction in response to TGFβ signaling.PR-domain-containing Mds1-Evi1 is critical for long-term hematopoietic stem cell function.Transcriptional profiling reveals developmental relationship and distinct biological functions of CD16+ and CD16- monocyte subsets.Massively parallel signature sequencing and bioinformatics analysis identifies up-regulation of TGFBI and SOX4 in human glioblastoma.DNA methylation of the first exon is tightly linked to transcriptional silencingHematopoietic progenitor cell regulation by CD4+CD25+ T cells.Defining the localization and molecular characteristic of minor salivary gland label-retaining cells.Imprinted genes that regulate early mammalian growth are coexpressed in somatic stem cells.Activation of cell cycle arrest and apoptosis by the proto-oncogene Pim-2.HDAC6 deacetylase activity is required for hypoxia-induced invadopodia formation and cell invasion.p19 INK4d controls hematopoietic stem cells in a cell-autonomous manner during genotoxic stress and through the microenvironment during aging.Can systems biology understand pathway activation? Gene expression signatures as surrogate markers for understanding the complexity of pathway activation.Clonal-level responses of functionally distinct hematopoietic stem cells to trophic factors.Convergence of hypoxia and TGFβ pathways on cell cycle regulation in human hematopoietic stem/progenitor cells.FHL2 regulates hematopoietic stem cell functions under stress conditionsTGF-β signaling and its role in the regulation of hematopoietic stem cells.Promiscuous and lineage-specific roles of cell cycle regulators in haematopoiesisThe role of novel and known extracellular matrix and adhesion molecules in the homeostatic and regenerative bone marrow microenvironmentGenome-wide profiling reveals transcriptional repression of MYC as a core component of NR4A tumor suppression in acute myeloid leukemia.Necdin, a p53 target gene, regulates the quiescence and response to genotoxic stress of hematopoietic stem/progenitor cells.Linking Hematopoietic Differentiation to Co-Expressed Sets of Pluripotency-Associated and Imprinted Genes and to Regulatory microRNA-Transcription Factor Motifs.Deregulated TGF-beta signaling in leukemogenesis.Microenvironments dictating tumor cell dormancySignaling pathways in self-renewing hematopoietic and leukemic stem cells: do all stem cells need a niche?TGFβ restores hematopoietic homeostasis after myelosuppressive chemotherapy.Regulation of tumor cell dormancy by tissue microenvironments and autophagy.Bi-compartmental communication contributes to the opposite proliferative behavior of Notch1-deficient hair follicle and epidermal keratinocytes.Ordered arrays of native chromatin molecules for high-resolution imaging and analysis.BD-Func: a streamlined algorithm for predicting activation and inhibition of pathways.Dietary antioxidants protect hematopoietic cells and improve animal survival after total-body irradiation
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P2860
Transforming growth factor beta-induced cell cycle arrest of human hematopoietic cells requires p57KIP2 up-regulation.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 11 October 2004
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Transforming growth factor bet ...... equires p57KIP2 up-regulation.
@en
Transforming growth factor bet ...... equires p57KIP2 up-regulation.
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type
label
Transforming growth factor bet ...... equires p57KIP2 up-regulation.
@en
Transforming growth factor bet ...... equires p57KIP2 up-regulation.
@nl
prefLabel
Transforming growth factor bet ...... equires p57KIP2 up-regulation.
@en
Transforming growth factor bet ...... equires p57KIP2 up-regulation.
@nl
P2860
P356
P1476
Transforming growth factor bet ...... requires p57KIP2 up-regulation
@en
P2093
Piernicola Boccuni
Stephen D Nimer
P2860
P304
15231-15236
P356
10.1073/PNAS.0406771101
P407
P577
2004-10-11T00:00:00Z