The reverse operation of Na(+)/Cl(-)-coupled neurotransmitter transporters--why amphetamines take two to tango.
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Toxicity of amphetamines: an updateMechanisms of dopamine transporter regulation in normal and disease statesThe designer methcathinone analogs, mephedrone and methylone, are substrates for monoamine transporters in brain tissueBehavioral, biological, and chemical perspectives on atypical agents targeting the dopamine transporterThe preclinical pharmacology of mephedrone; not just MDMA by another name.The N terminus of monoamine transporters is a lever required for the action of amphetaminesSympathetic nerves and the endothelium influence the vasoconstrictor effect of low concentrations of ouabain in pressurized small arteries.The ugly side of amphetamines: short- and long-term toxicity of 3,4-methylenedioxymethamphetamine (MDMA, 'Ecstasy'), methamphetamine and D-amphetamine.The high-affinity binding site for tricyclic antidepressants resides in the outer vestibule of the serotonin transporter.Studies of the biogenic amine transporters. 14. Identification of low-efficacy "partial" substrates for the biogenic amine transportersEffects of amphetamine on subcellular distribution of dopamine and DOPAC.Eph/ephrin interactions modulate vascular sympathetic innervation.In vivo amphetamine action is contingent on αCaMKIIBaths salts, spice, and related designer drugs: the science behind the headlines.Regulation of monoamine transporters: Role of transporter phosphorylation.Brain serotonergic circuitriesProbing binding pocket of serotonin transporter by single molecular force spectroscopy on living cells.Effects of MDMA and related analogs on plasma 5-HT: relevance to 5-HT transporters in blood and brain.Amphetamines, new psychoactive drugs and the monoamine transporter cycle.Dopamine transporter phosphorylation site threonine 53 regulates substrate reuptake and amphetamine-stimulated efflux.Phosphorylation of dopamine transporter serine 7 modulates cocaine analog binding.Psychoactive "bath salts": not so soothing.Powerful cocaine-like actions of 3,4-methylenedioxypyrovalerone (MDPV), a principal constituent of psychoactive 'bath salts' productsAmphetamine actions at the serotonin transporter rely on the availability of phosphatidylinositol-4,5-bisphosphateMDMA (3,4-Methylenedioxymethamphetamine) Analogues as Tools to Characterize MDMA-Like Effects: An Approach to Understand Entactogen PharmacologyDopamine Transporter Amino and Carboxyl Termini Synergistically Contribute to Substrate and Inhibitor Affinities.Neuroteratology and Animal Modeling of Brain Disorders.Reporting Two Fatalities Associated with the Use of 4-Methylethcathinone (4-MEC) and a Review of the Literature.Application of a Combined Approach to Identify New Psychoactive Street Drugs and Decipher Their Mechanisms at Monoamine Transporters.'Second-generation' mephedrone analogs, 4-MEC and 4-MePPP, differentially affect monoamine transporter function.Editor's Highlight: Characterization of Hepatotoxicity Mechanisms Triggered by Designer Cathinone Drugs (β-Keto Amphetamines).Mutations in the carboxyl-terminal SEC24 binding motif of the serotonin transporter impair folding of the transporter.Aminorex, a metabolite of the cocaine adulterant levamisole, exerts amphetamine like actions at monoamine transporters.Ca(2+)/calmodulin-dependent protein kinase IIα (αCaMKII) controls the activity of the dopamine transporter: implications for Angelman syndrome.A quantitative model of amphetamine action on the 5-HT transporter.Probing the Selectivity of Monoamine Transporter Substrates by Means of Molecular Modeling.A combined approach using transporter-flux assays and mass spectrometry to examine psychostimulant street drugs of unknown content.Allosteric modulation of human dopamine transporter activity under conditions promoting its dimerization.Cross-Generational trans Fat Consumption Favors Self-Administration of Amphetamine and Changes Molecular Expressions of BDNF, DAT, and D1/D2 Receptors in the Cortex and Hippocampus of Rats.Regulator of G protein signaling-12 modulates the dopamine transporter in ventral striatum and locomotor responses to psychostimulants.
P2860
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P2860
The reverse operation of Na(+)/Cl(-)-coupled neurotransmitter transporters--why amphetamines take two to tango.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh
2009年學術文章
@zh-hant
name
The reverse operation of Na
@nl
The reverse operation of Na(+) ...... mphetamines take two to tango.
@en
type
label
The reverse operation of Na
@nl
The reverse operation of Na(+) ...... mphetamines take two to tango.
@en
prefLabel
The reverse operation of Na
@nl
The reverse operation of Na(+) ...... mphetamines take two to tango.
@en
P2860
P1476
The reverse operation of Na(+) ...... amphetamines take two to tango
@en
P2093
Harald H Sitte
Michael Freissmuth
P2860
P304
P356
10.1111/J.1471-4159.2009.06474.X
P407
P577
2009-11-05T00:00:00Z