Hypermutation at the immunoglobulin heavy chain locus in a pre-B-cell line. - Wikidata - wikimedia - TriplyDB

Hypermutation at the immunoglobulin heavy chain locus in a pre-B-cell line.

Hypermutation at the immunoglobulin heavy chain locus in a pre-B-cell line.

http://www.wikidata.org/entity/Q37675025

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Slow, stochastic transgene repression with properties of a timer Looping out and deletion mechanism for the immunoglobulin heavy-chain class switch.Identification of mutant monoclonal antibodies with increased antigen binding An immunoglobulin mutator that targets G.C base pairs.C3d regulates immune checkpoint blockade and enhances antitumor immunity.Fidelity of a human cell DNA replication complex.Stepwise intraclonal maturation of antibody affinity through somatic hypermutation The rate of mutation of a single gene.Mutations in HIV-1 reverse transcriptase affect the errors made in a single cycle of viral replication.Characterization of a complete immunoglobulin heavy-chain variable region germ-line gene of rainbow trout.VH gene family utilization in colonies derived from B and pre-B cells detected by the RNA colony blot assay Genome-wide somatic hypermutation.Patterns of somatic mutations in immunoglobulin variable genes Immunoglobulin variable region hypermutation in hybrids derived from a pre-B- and a myeloma cell line Nature, position, and frequency of mutations made in a single cycle of HIV-1 replication.In vivo and in vitro studies of immunoglobulin gene somatic hypermutation.Allelic inclusion in a pre-B-cell line that generates immunoglobulin heavy chain genes in vitro Cancer genes: rare recombinants instead of activated oncogenes (a review).Somatic diversification of S107 from an antiphosphocholine to an anti-DNA autoantibody is due to a single base change in its heavy chain variable region.High rates of deletions in the constant region segment of the immunoglobulin mu gene.Multiple point mutations in a shuttle vector propagated in human cells: evidence for an error-prone DNA polymerase activity.TACI deficiency impairs sustained Blimp-1 expression in B cells decreasing long-lived plasma cells in the bone marrow.Rearrangements of DNA mediated by terminal transferase.Characterization of the immunoglobulin heavy chain complementarity determining region (CDR)-III sequences from human B cell precursor acute lymphoblastic leukemia cells.Differential V region mutation of two transfected Ig genes and their interaction in cultured B cell lines The Ig mutator is dependent on the presence, position, and orientation of the large intron enhancer.Unequal sister chromatid exchange. A mechanism affecting Ig gene arrangement and expression.Spontaneous loss and alteration of antigen receptor expression in mature CD4+ T cells.Continuing rearrangement but absence of somatic hypermutation in immunoglobulin genes of human B cell precursor leukemia.Relationship of variable region genes expressed by a human B cell lymphoma secreting pathologic anti-Pr2 erythrocyte autoantibodies.Functional immunoglobulin light chain genes are replaced by ongoing rearrangements of germline V kappa genes to downstream J kappa segment in a murine B cell line.An experimental solution for the Luria-Delbrück fluctuation problem in measuring hypermutation rates.Sequence dependent hypermutation of the immunoglobulin heavy chain in cultured B cells.DNA rearrangement causes a high rate of spontaneous mutation at the immunoglobulin heavy-chain locus of a mouse myeloma cell line.A role for host activation-induced cytidine deaminase in innate immune defense against KSHV.High rate of somatic point mutation in vitro in and near the variable-region segment of an immunoglobulin heavy chain gene Restricted ultraviolet mutational spectrum in a shuttle vector propagated in xeroderma pigmentosum cells.Somatic mutation in constant regions of mouse lambda 1 light chains B lymphocyte progenitors in mouse bone marrow.Differences in mutagenesis during minus strand, plus strand and strand transfer (recombination) synthesis of the HIV-1 gene in vitro

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Hypermutation at the immunoglobulin heavy chain locus in a pre-B-cell line.

http://www.wikidata.org/entity/Q37675025

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on January 1985

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Hypermutation at the immunoglobulin heavy chain locus in a pre-B-cell line.

@en

Hypermutation at the immunoglobulin heavy chain locus in a pre-B-cell line.

@nl

type

label

Hypermutation at the immunoglobulin heavy chain locus in a pre-B-cell line.

@en

Hypermutation at the immunoglobulin heavy chain locus in a pre-B-cell line.

@nl

prefLabel

Hypermutation at the immunoglobulin heavy chain locus in a pre-B-cell line.

@en

Hypermutation at the immunoglobulin heavy chain locus in a pre-B-cell line.

@nl

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Hypermutation at the immunoglobulin heavy chain locus in a pre-B-cell line.

@en

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Burrows PD

http://www.w3.org/2001/XMLSchema#string

Steinberg C

http://www.w3.org/2001/XMLSchema#string

Wabl M

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von Gabain A

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P2860

DNA sequencing with chain-terminating inhibitors

Somatic generation of antibody diversity

A new pair of M13 vectors for selecting either DNA strand of double-digest restriction fragments

Inheritance of spontaneous mutability in yeast.

Expression of mu and gamma immunoglobulin heavy chains in different cells of a cloned mouse lymphoid line

Assignment of genes for immunoglobulin kappa and heavy chains to chromosomes 6 and 12 in mouse

Allelic inclusion in the pre-B-cell line 18-81.

Expression of immunoglobulin heavy chain at a high level in the absence of a proposed immunoglobulin enhancer element in cis.

Somatic mutation in a cultured mouse myeloma cell affects antigen binding

Galactan-binding antibodies. Diversity and structure of idiotypes

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479-482

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scholarly article

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10.1073/PNAS.82.2.479

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2

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82

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1985-01-01T00:00:00Z

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19244250

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3918310

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397062

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