Mammalian target of rapamycin hyperactivity mediates the detrimental effects of a high sucrose diet on Alzheimer's disease pathology
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Menopause, obesity and inflammation: interactive risk factors for Alzheimer's diseaseMetformin promotes tau aggregation and exacerbates abnormal behavior in a mouse model of tauopathyAdministration of a selective β2 adrenergic receptor antagonist exacerbates neuropathology and cognitive deficits in a mouse model of Alzheimer's diseaseGenetic reduction of mammalian target of rapamycin ameliorates Alzheimer's disease-like cognitive and pathological deficits by restoring hippocampal gene expression signatureObesity Accelerates Alzheimer-Related Pathology in APOE4 but not APOE3 Mice.Divergent tissue and sex effects of rapamycin on the proteasome-chaperone network of old mice.Sterols from Mytilidae show anti-aging and neuroprotective effects via anti-oxidative activityHigh-fat feeding impairs nutrient sensing and gut brain integration in the caudomedial nucleus of the solitary tract in mice.Reducing Ribosomal Protein S6 Kinase 1 Expression Improves Spatial Memory and Synaptic Plasticity in a Mouse Model of Alzheimer's Disease.Dietary and donepezil modulation of mTOR signaling and neuroinflammation in the brain.Mechanisms of oxidative stress resistance in the brain: Lessons learned from hypoxia tolerant extremophilic vertebrates.Red peppers with moderate and severe pungency prevent the memory deficit and hepatic insulin resistance in diabetic rats with Alzheimer's diseasemTOR in Brain Physiology and Pathologies.Obesity and sex interact in the regulation of Alzheimer's disease.Central insulin dysregulation and energy dyshomeostasis in two mouse models of Alzheimer's disease.Targeting mTOR to reduce Alzheimer-related cognitive decline: from current hits to future therapies.A Brief Overview of Tauopathy: Causes, Consequences, and Therapeutic Strategies.Dyrk1 inhibition improves Alzheimer's disease-like pathology.Exosomal biomarkers of brain insulin resistance associated with regional atrophy in Alzheimer's disease.Metabolic clues to salubrious longevity in the brain of the longest-lived rodent: the naked mole-rat.Genetic reduction of Nrf2 exacerbates cognitive deficits in a mouse model of Alzheimer's disease.Impact of enriched environment on production of tau, amyloid precursor protein and, amyloid-β peptide in high-fat and high-sucrose-fed rats.
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P2860
Mammalian target of rapamycin hyperactivity mediates the detrimental effects of a high sucrose diet on Alzheimer's disease pathology
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 14 December 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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name
Mammalian target of rapamycin ...... Alzheimer's disease pathology
@en
Mammalian target of rapamycin ...... Alzheimer's disease pathology.
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type
label
Mammalian target of rapamycin ...... Alzheimer's disease pathology
@en
Mammalian target of rapamycin ...... Alzheimer's disease pathology.
@nl
prefLabel
Mammalian target of rapamycin ...... Alzheimer's disease pathology
@en
Mammalian target of rapamycin ...... Alzheimer's disease pathology.
@nl
P2093
P2860
P1476
Mammalian target of rapamycin ...... Alzheimer's disease pathology
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P2093
Angelica Salinas
Miranda E Orr
Rochelle Buffenstein
Salvatore Oddo
P2860
P304
P356
10.1016/J.NEUROBIOLAGING.2013.12.006
P577
2013-12-14T00:00:00Z