Repression of a matrix metalloprotease gene by E1A correlates with its ability to bind to cell type-specific transcription factor AP-2.
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The AP-2 family of transcription factorsA cellular repressor of E1A-stimulated genes that inhibits activation by E2FGAS41 interacts with transcription factor AP-2beta and stimulates AP-2beta-mediated transactivationA synergistic interaction of transcription factors AP2 and YB-1 regulates gelatinase A enhancer-dependent transcriptionAdenovirus E1A inhibits cardiac myocyte-specific gene expression through its amino terminusAP-2-null cells disrupt morphogenesis of the eye, face, and limbs in chimeric miceTranscription factor AP-2gamma regulates murine adenosine deaminase gene expression during placental developmentp300/cAMP-responsive element-binding protein interactions with ets-1 and ets-2 in the transcriptional activation of the human stromelysin promoterIdentification of functional TFAP2A and SP1 binding sites in new TFAP2A-modulated genesA novel function of adenovirus E1A is required to overcome growth arrest by the CDK2 inhibitor p27(Kip1).The N terminus of adenovirus type 12 E1A inhibits major histocompatibility complex class I expression by preventing phosphorylation of NF-kappaB p65 Ser276 through direct binding.Combinatorial interactions of p53, activating protein-2, and YB-1 with a single enhancer element regulate gelatinase A expression in neoplastic cells.Transgenic expression in mouse lung reveals distinct biological roles for the adenovirus type 5 E1A 243- and 289-amino-acid proteinsMyc represses transcription of the growth arrest gene gas1Activator protein-2 in carcinogenesis with a special reference to breast cancer--a mini review.Intrinsic structural disorder in adenovirus E1A: a viral molecular hub linking multiple diverse processes.The critical protein interactions and structures that elicit growth deregulation in cancer and viral replication.The minimal promoter of the human alpha 3 nicotinic receptor subunit gene. Molecular and functional characterization.BRCA1 signals ARF-dependent stabilization and coactivation of p53.Database of mutations within the adenovirus 5 E1A oncogene.Transcriptional activation by p53 of the human type IV collagenase (gelatinase A or matrix metalloproteinase 2) promoter.Apoptosis induction by activator protein 2alpha involves transcriptional repression of Bcl-2.Efficient growth inhibition of HPV 16 E6-expressing cells by an adenovirus-expressing p53 homologue p73beta.Gene expression profiling in ataxin-3 expressing cell lines reveals distinct effects of normal and mutant ataxin-3.Cell cycle arrest and apoptosis induction by activator protein 2alpha (AP-2alpha) and the role of p53 and p21WAF1/CIP1 in AP-2alpha-mediated growth inhibition.Regulation of the p53 homolog p73 by adenoviral oncogene E1A.Matrix metalloproteinase 2 (MMP2) and MMP9 are produced by kidney collecting duct principal cells but are differentially regulated by SV40 large-T, arginine vasopressin, and epidermal growth factor.Evidence for modulation of BAG3 by polyomavirus JC early protein.A multicenter phase II study of tgDCC-E1A for the intratumoral treatment of patients with recurrent head and neck squamous cell carcinoma.The transcription factors Sp1, Sp3, and AP-2 are required for constitutive matrix metalloproteinase-2 gene expression in astroglioma cells.Hacking the Cell: Network Intrusion and Exploitation by Adenovirus E1A.The retinoblastoma-related Rb2/p130 gene is an effector downstream of AP-2 during neural differentiation.
P2860
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P2860
Repression of a matrix metalloprotease gene by E1A correlates with its ability to bind to cell type-specific transcription factor AP-2.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on April 1996
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Repression of a matrix metallo ...... fic transcription factor AP-2.
@en
Repression of a matrix metallo ...... fic transcription factor AP-2.
@nl
type
label
Repression of a matrix metallo ...... fic transcription factor AP-2.
@en
Repression of a matrix metallo ...... fic transcription factor AP-2.
@nl
prefLabel
Repression of a matrix metallo ...... fic transcription factor AP-2.
@en
Repression of a matrix metallo ...... fic transcription factor AP-2.
@nl
P2093
P2860
P356
P1476
Repression of a matrix metallo ...... fic transcription factor AP-2.
@en
P2093
B Thimmapaya
G Jayaraman
K Somasundaram
T Williams
P2860
P304
P356
10.1073/PNAS.93.7.3088
P407
P577
1996-04-01T00:00:00Z