Regulation of experimental autoimmune encephalomyelitis by TPL-2 kinase.

Regulation of experimental autoimmune encephalomyelitis by TPL-2 kinase.

Item
http://www.wikidata.org/entity/Q37692262
IκB kinase-induced interaction of TPL-2 kinase with 14-3-3 is essential for Toll-like receptor activation of ERK-1 and -2 MAP kinasesMicrowave & magnetic (M2) proteomics reveals CNS-specific protein expression waves that precede clinical symptoms of experimental autoimmune encephalomyelitis.TLR and TNF-R1 activation of the MKK3/MKK6-p38α axis in macrophages is mediated by TPL-2 kinase.Tumor progression locus 2 differentially regulates IFNγ and IL-17 production by effector CD4+ T cells in a T cell transfer model of colitisTPL-2 Regulates Macrophage Lipid Metabolism and M2 Differentiation to Control TH2-Mediated Immunopathology.Aberrant expression of COT is related to recurrence of papillary thyroid cancer.Tumor progression locus 2 reduces severe allergic airway inflammation by inhibiting Ccl24 production in dendritic cells.Tpl2 promotes innate cell recruitment and effector T cell differentiation to limit Citrobacter rodentium burden and dissemination.TPL-2 restricts Ccl24-dependent immunity to Heligmosomoides polygyrus.TPL2 Kinase Is a Crucial Signaling Factor and Mediator of NKT Effector Cytokine Expression in Immune-Mediated Liver Injury.Tumor Progression Locus 2 (Tpl2) Activates the Mammalian Target of Rapamycin (mTOR) Pathway, Inhibits Forkhead Box P3 (FoxP3) Expression, and Limits Regulatory T Cell (Treg) Immunosuppressive Functions.The Crystal Structure of Cancer Osaka Thyroid Kinase Reveals an Unexpected Kinase Domain Fold.A TPL2 (MAP3K8) disease-risk polymorphism increases TPL2 expression thereby leading to increased pattern recognition receptor-initiated caspase-1 and caspase-8 activation, signalling and cytokine secretion.TPL2 mediates IL-17R signaling in neuroinflammation.Assaying kinase activity of the TPL-2/NF-κB1 p105/ABIN-2 complex using an optimal peptide substrate.A20-binding inhibitor of NF-κB (ABIN) 2 negatively regulates allergic airway inflammation
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Regulation of experimental autoimmune encephalomyelitis by TPL-2 kinase.

Item
http://www.wikidata.org/entity/Q37692262
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 17 March 2014
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Regulation of experimental autoimmune encephalomyelitis by TPL-2 kinase.
@en
Regulation of experimental autoimmune encephalomyelitis by TPL-2 kinase.
@nl
type
label
Regulation of experimental autoimmune encephalomyelitis by TPL-2 kinase.
@en
Regulation of experimental autoimmune encephalomyelitis by TPL-2 kinase.
@nl
prefLabel
Regulation of experimental autoimmune encephalomyelitis by TPL-2 kinase.
@en
Regulation of experimental autoimmune encephalomyelitis by TPL-2 kinase.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P921
P932
P356
P1433
P1476
Regulation of experimental autoimmune encephalomyelitis by TPL-2 kinase.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P921
P932