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Akt and mTOR in B Cell Activation and DifferentiationNuclear ErbB2 enhances translation and cell growth by activating transcription of ribosomal RNA genesRegulation of global and specific mRNA translation by the mTOR signaling pathwayCould the eIF2α-Independent Translation Be the Achilles Heel of Cancer?What a tangled web we weave: emerging resistance mechanisms to inhibition of the phosphoinositide 3-kinase pathwayWhy is start codon selection so precise in eukaryotes?Serine, glycine and one-carbon units: cancer metabolism in full circleTrespassing cancer cells: 'fingerprinting' invasive protrusions reveals metastatic culpritsThe translational factor eIF3f: the ambivalent eIF3 subunitTargeting translation initiation in breast cancerCrystal structure of the eukaryotic 40S ribosomal subunit in complex with initiation factor 1Structural and functional characterization of Rpn12 identifies residues required for Rpn10 proteasome incorporationStructure of the eukaryotic translation initiation factor eIF4E in complex with 4EGI-1 reveals an allosteric mechanism for dissociating eIF4GPSMB8 and PBK as potential gastric cancer subtype-specific biomarkers associated with prognosis.Cell growth control by stable Rbg2/Gir2 complex formation under amino acid starvation.eIF3 targets cell-proliferation messenger RNAs for translational activation or repressionPDK1-SGK1 Signaling Sustains AKT-Independent mTORC1 Activation and Confers Resistance to PI3Kα InhibitionTwo RNA-binding motifs in eIF3 direct HCV IRES-dependent translationVersatility of RNA-Binding Proteins in CancerAlternative pre-mRNA splicing regulation in cancer: pathways and programs unhingedInflammatory conditions induce IRES-dependent translation of cyp24a1Effects of Interferons and Viruses on MetabolismBlood translation elongation factor-1δ is a novel marker for cadmium exposureAndrogen signaling promotes translation of TMEFF2 in prostate cancer cells via phosphorylation of the α subunit of the translation initiation factor 2Detection of rapalog-mediated therapeutic response in renal cancer xenografts using ⁶⁴Cu-bevacizumab immunoPETA novel mouse model for inhibition of DOHH-mediated hypusine modification reveals a crucial function in embryonic development, proliferation and oncogenic transformationTherapeutic potential of the translation inhibitor silvestrol in hepatocellular cancerTargeting eukaryotic translation in mesothelioma cells with an eIF4E-specific antisense oligonucleotideLmaPA2G4, a homolog of human Ebp1, is an essential gene and inhibits cell proliferation in L. majorResistance to mTOR kinase inhibitors in lymphoma cells lacking 4EBP1Differential Proteome Analysis Identifies TGF-β-Related Pro-Metastatic Proteins in a 4T1 Murine Breast Cancer ModelEukaryotic translation initiation factor 3, subunit a, regulates the extracellular signal-regulated kinase pathwayeIF6 coordinates insulin sensitivity and lipid metabolism by coupling translation to transcriptionThe m subunit of murine translation initiation factor eIF3 maintains the integrity of the eIF3 complex and is required for embryonic development, homeostasis, and organ size controlThe small molecule '1-(4-biphenylylcarbonyl)-4-(5-bromo-2-methoxybenzyl) piperazine oxalate' and its derivatives regulate global protein synthesis by inactivating eukaryotic translation initiation factor 2-alphaForced expression of the DEK-NUP214 fusion protein promotes proliferation dependent on upregulation of mTORPlakophilin-associated RNA-binding proteins in prostate cancer and their implications in tumor progression and metastasis.Translation initiation factor eIF3b expression in human cancer and its role in tumor growth and lung colonizationThree distinct ribosome assemblies modulated by translation are the building blocks of polysomes.Identification of phenotype-relevant differentially expressed genes in breast cancer demonstrates enhanced quantile discretization protocol's utility in multi-platform microarray data integration.
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description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on April 2010
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Translational control in cancer.
@en
Translational control in cancer.
@nl
type
label
Translational control in cancer.
@en
Translational control in cancer.
@nl
prefLabel
Translational control in cancer.
@en
Translational control in cancer.
@nl
P2860
P356
P1476
Translational control in cancer
@en
P2093
Deborah Silvera
Silvia C Formenti
P2860
P2888
P304
P356
10.1038/NRC2824
P407
P577
2010-04-01T00:00:00Z