The envA permeability/cell division gene of Escherichia coli encodes the second enzyme of lipid A biosynthesis. UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase.
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Lipid A modification systems in gram-negative bacteriaLipopolysaccharide endotoxinsCrystal structure of LpxC, a zinc-dependent deacetylase essential for endotoxin biosynthesisRegulated Control of the Assembly and Diversity of LPS by Noncoding sRNAsBinding of Uridine 5‘-Diphosphate in the “Basic Patch” of the Zinc Deacetylase LpxC and Implications for Substrate Binding † , ‡Structural basis for the acyl chain selectivity and mechanism of UDP-N-acetylglucosamine acyltransferaseCrystal structure of LpxC from Pseudomonas aeruginosa complexed with the potent BB-78485 inhibitorStructure of the Metal-Dependent Deacetylase LpxC from Yersinia enterocolitica Complexed with the Potent Inhibitor CHIR-090,Cloning, expression, and purification of UDP-3-O-acyl-GlcNAc deacetylase from Pseudomonas aeruginosa: a metalloamidase of the lipid A biosynthesis pathwayA Complete Pathway Model for Lipid A Biosynthesis in Escherichia coliRelaxed acyl chain specificity of Bordetella UDP-N-acetylglucosamine acyltransferases.The Escherichia coli gene encoding the UDP-2,3-diacylglucosamine pyrophosphatase of lipid A biosynthesis.Antibacterial activities and characterization of novel inhibitors of LpxC.Integration of curated databases to identify genotype-phenotype associations.Residue ionization in LpxC directly observed by 67Zn NMR spectroscopy.Bacterial sources and sinks of isoprene, a reactive atmospheric hydrocarbon.Active site metal ion in UDP-3-O-((R)-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase (LpxC) switches between Fe(II) and Zn(II) depending on cellular conditions.UDP-3-O-((R)-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase functions through a general acid-base catalyst pair mechanism.Mechanism and inhibition of LpxC: an essential zinc-dependent deacetylase of bacterial lipid A synthesis.Cellular responses during morphological transformation in Azospirillum brasilense and Its flcA knockout mutantUse of in vivo induced antigen technology to identify genes from Aeromonas salmonicida subsp. salmonicida that are specifically expressed during infection of the rainbow trout Oncorhynchus mykiss.Dissecting Escherichia coli outer membrane biogenesis using differential proteomics.Cell rejuvenation and social behaviors promoted by LPS exchange in myxobacteriaGenetic interaction between the Escherichia coli AcpT phosphopantetheinyl transferase and the YejM inner membrane protein.Function of the htrB high temperature requirement gene of Escherichia coli in the acylation of lipid A: HtrB catalyzed incorporation of laurate.Mechanistic inferences from the binding of ligands to LpxC, a metal-dependent deacetylase.Defining the mode of action of tetramic acid antibacterials derived from Pseudomonas aeruginosa quorum sensing signals.On the essentiality of lipopolysaccharide to Gram-negative bacteria.The nucleotide-binding site of Aquifex aeolicus LpxC.Mutant Alleles of lptD Increase the Permeability of Pseudomonas aeruginosa and Define Determinants of Intrinsic Resistance to Antibiotics.Antibacterial Drug Discovery Targeting the Lipopolysaccharide Biosynthetic Enzyme LpxC.Structure, inhibition, and regulation of essential lipid A enzymes.Escherichia coli strains blocked in Tat-dependent protein export exhibit pleiotropic defects in the cell envelope.Unique biological properties and molecular mechanism of 5,6-bridged quinolones.FtsH-mediated coordination of lipopolysaccharide biosynthesis in Escherichia coli correlates with the growth rate and the alarmone (p)ppGpp.asmB, a suppressor locus for assembly-defective OmpF mutants of Escherichia coli, is allelic to envA (lpxC).A mutation in the ftsK gene of Escherichia coli affects cell-cell separation, stationary-phase survival, stress adaptation, and expression of the gene encoding the stress protein UspA.Activation of Escherichia coli UDP-3-O-[(R)-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase by Fe2+ yields a more efficient enzyme with altered ligand affinity.Control of lipopolysaccharide biosynthesis by FtsH-mediated proteolysis of LpxC is conserved in enterobacteria but not in all gram-negative bacteria.LpxC Inhibitors: Design, Synthesis, and Biological Evaluation of Oxazolidinones as Gram-negative Antibacterial Agents
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P2860
The envA permeability/cell division gene of Escherichia coli encodes the second enzyme of lipid A biosynthesis. UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on December 1995
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
The envA permeability/cell div ...... lipid A biosynthesis. UDP-3-O-
@nl
The envA permeability/cell div ...... acetylglucosamine deacetylase.
@en
type
label
The envA permeability/cell div ...... lipid A biosynthesis. UDP-3-O-
@nl
The envA permeability/cell div ...... acetylglucosamine deacetylase.
@en
prefLabel
The envA permeability/cell div ...... lipid A biosynthesis. UDP-3-O-
@nl
The envA permeability/cell div ...... acetylglucosamine deacetylase.
@en
P2093
P2860
P356
P1476
The envA permeability/cell div ...... acetylglucosamine deacetylase.
@en
P2093
Anderson MS
Bramhill D
Eveland SS
P2860
P304
30384-30391
P356
10.1074/JBC.270.51.30384
P407
P577
1995-12-01T00:00:00Z