Stability and binding properties of a modified thrombin binding aptamer.
about
Molecular Selection, Modification and Development of Therapeutic Oligonucleotide AptamersThrombin-aptamer recognition: a revealed ambiguityHigh-resolution structures of two complexes between thrombin and thrombin-binding aptamer shed light on the role of cations in the aptamer inhibitory activityComparison of the 'chemical' and 'structural' approaches to the optimization of the thrombin-binding aptamerElectrical Stimulus Controlled Binding/Unbinding of Human Thrombin-Aptamer Complex.Development of single-stranded DNA aptamers for specific Bisphenol a detectionImproved thrombin binding aptamer by incorporation of a single unlocked nucleic acid monomer.Selective light-triggered release of DNA from gold nanorods switches blood clotting on and off.Nucleic Acid Ligands With Protein-like Side Chains: Modified Aptamers and Their Use as Diagnostic and Therapeutic AgentsCross-talk between prion protein and quadruplex-forming nucleic acids: a dynamic complex formation.Applications of isothermal titration calorimetry in biophysical studies of G-quadruplexes.Conformationally rigid nucleoside probes help understand the role of sugar pucker and nucleobase orientation in the thrombin-binding aptamerHuman Norovirus Aptamer Exhibits High Degree of Target Conformation-Dependent Binding Similar to That of Receptors and Discriminates Particle FunctionalityAptamers as therapeutics in cardiovascular diseases.Structural Characterization of a Thrombin-Aptamer Complex by High Resolution Native Top-Down Mass Spectrometry.Optimization of fluorescent 8-heteroaryl-guanine probes for monitoring protein-mediated duplex → G-quadruplex exchange.Site-specific replacement of the thymine methyl group by fluorine in thrombin binding aptamer significantly improves structural stability and anticoagulant activity.Anomeric DNA quadruplexes.Stability and bioactivity of thrombin binding aptamers modified with D-/L-isothymidine in the loop regions.Unfolding and conformational variations of thrombin-binding DNA aptamers: synthesis, circular dichroism and molecular dynamics simulations.Harnessing G-tetrad scaffolds within G-quadruplex forming aptamers for fluorescence detection strategies.Interaction of water with the G-quadruplex loop contributes to the binding energy of G-quadruplex to protein.Quantifying the nanomachinery of the nanoparticle-biomolecule interface.Hydration is required in DNA G-quadruplex-protein binding.Crystallization and preliminary X-ray analysis of the complex of human alpha-thrombin with a modified thrombin-binding aptamer.Structural transformation induced by locked nucleic acid or 2'-O-methyl nucleic acid site-specific modifications on thrombin binding aptamer.Biophysical properties, thermal stability and functional impact of 8-oxo-7,8-dihydroguanine on oligonucleotides of RNA-a study of duplex, hairpins and the aptamer for preQ1 as models.In What Ways Do Synthetic Nucleotides and Natural Base Lesions Alter the Structural Stability of G-Quadruplex Nucleic Acids?A Universal Base in a Specific Role: Tuning up a Thrombin Aptamer with 5-Nitroindole.The Bound Structures of 17β-Estradiol-Binding Aptamers.Thermodynamic, Anticoagulant, and Antiproliferative Properties of Thrombin Binding Aptamer Containing Novel UNA Derivative.Identification of G-quadruplex forming sequences in three manatee papillomaviruses.Multiplexed protein detection using an affinity aptamer amplification assay.Nanogravimetric and Optical Characterizations of Thrombin Interaction with a Self-Assembled Thiolated Aptamer
P2860
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P2860
Stability and binding properties of a modified thrombin binding aptamer.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Stability and binding properties of a modified thrombin binding aptamer.
@en
type
label
Stability and binding properties of a modified thrombin binding aptamer.
@en
prefLabel
Stability and binding properties of a modified thrombin binding aptamer.
@en
P2860
P50
P1433
P1476
Stability and binding properties of a modified thrombin binding aptamer.
@en
P2860
P304
P356
10.1529/BIOPHYSJ.107.117382
P407
P577
2007-09-21T00:00:00Z