Type 1 11beta -hydroxysteroid dehydrogenase mediates glucocorticoid activation and insulin release in pancreatic islets.
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The role of glucocorticoid action in the pathophysiology of the Metabolic SyndromeAn intact eight-membered water chain in drosophilid alcohol dehydrogenases is essential for optimal enzyme activityMifepristone reduces insulin resistance in patient volunteers with adrenal incidentalomas that secrete low levels of cortisol: a pilot studyModulation of pancreatic islets-stress axis by hypothalamic releasing hormones and 11beta-hydroxysteroid dehydrogenaseMetabolic conversion as a pre-receptor control mechanism for lipophilic hormones.Glut4 is upregulated despite decreased insulin signaling during prolonged fasting in northern elephant seal pups.Decreased 11β-Hydroxysteroid Dehydrogenase 1 Level and Activity in Murine Pancreatic Islets Caused by Insulin-Like Growth Factor I Overexpression.Glucocorticoid signalling affects pancreatic development through both direct and indirect effects.Tissue-specific dysregulation of 11beta-hydroxysteroid dehydrogenase type 1 and pathogenesis of the metabolic syndrome.Inhibition of 11beta-HSD1 as a novel treatment for the metabolic syndrome: do glucocorticoids play a role?11beta-HSD1 inhibition ameliorates metabolic syndrome and prevents progression of atherosclerosis in mice.Fluid secretion caused by aerolysin-like hemolysin of Aeromonas sobria in the intestines is due to stimulation of production of prostaglandin E2 via cyclooxygenase 2 by intestinal cellsMechanisms of disease: Selective inhibition of 11beta-hydroxysteroid dehydrogenase type 1 as a novel treatment for the metabolic syndrome.11β-hydroxysteroid dehydrogenases: intracellular gate-keepers of tissue glucocorticoid action.Analysis of Purified Pancreatic Islet Beta and Alpha Cell Transcriptomes Reveals 11β-Hydroxysteroid Dehydrogenase (Hsd11b1) as a Novel Disallowed Gene.Islet transplantation a decade later and strategies for filling a half-full glassPopulation pharmacokinetic/pharmacodynamic model of subcutaneous adipose 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) activity after oral administration of AMG 221, a selective 11β-HSD1 inhibitor.Optimal elevation of β-cell 11β-hydroxysteroid dehydrogenase type 1 is a compensatory mechanism that prevents high-fat diet-induced β-cell failure.Effects of glycyrrhetinic acid derivatives on hepatic and renal 11beta-hydroxysteroid dehydrogenase activities in rats.Comparative enzymology of 11 beta -hydroxysteroid dehydrogenase type 1 from glucocorticoid resistant (Guinea pig) versus sensitive (human) species.Changes in sex hormone-binding globulin and testosterone during weight loss and weight maintenance in abdominally obese men with the metabolic syndrome.The crystal structure of guinea pig 11beta-hydroxysteroid dehydrogenase type 1 provides a model for enzyme-lipid bilayer interactions.Reply to Liu et al.: Hypothalamic control of islets.Glucocorticoids Reprogram β-Cell Signaling to Preserve Insulin Secretion.Plasticity changes in adult metabolic homeostasis and tissue oxidative stress: neonatal programming by corticosterone and melatonin as deprogrammer.Correlation of sex hormone and androgen receptor with diabetes mellitus in elderly men.11-Beta-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitors in Type 2 diabetes mellitus and obesity
P2860
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P2860
Type 1 11beta -hydroxysteroid dehydrogenase mediates glucocorticoid activation and insulin release in pancreatic islets.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
2000年论文
@zh
2000年论文
@zh-cn
name
Type 1 11beta -hydroxysteroid ...... release in pancreatic islets.
@en
type
label
Type 1 11beta -hydroxysteroid ...... release in pancreatic islets.
@en
prefLabel
Type 1 11beta -hydroxysteroid ...... release in pancreatic islets.
@en
P2093
P2860
P356
P1476
Type 1 11beta -hydroxysteroid ...... release in pancreatic islets.
@en
P2093
Jörnvall H
Mårtensson E
Oppermann UC
P2860
P304
34841-34844
P356
10.1074/JBC.C000600200
P407
P50
P577
2000-11-01T00:00:00Z