High-performance affinity beads for identifying drug receptors.
about
Suppression of NF-kappaB-dependent gene expression by a hexamethylene bisacetamide-inducible protein HEXIM1 in human vascular smooth muscle cellsHEXIM1 forms a transcriptionally abortive complex with glucocorticoid receptor without involving 7SK RNA and positive transcription elongation factor bAnalysis of nuclear transport signals in the human apurinic/apyrimidinic endonuclease (APE1/Ref1).Regulatory role of human AP-endonuclease (APE1/Ref-1) in YB-1-mediated activation of the multidrug resistance gene MDR1.Interleukin enhancer-binding factor 3/NF110 is a target of YM155, a suppressant of survivinIdentification of NIPSNAP1 as a nocistatin-interacting protein involving pain transmissionA general mechanism for transcription regulation by Oct1 and Oct4 in response to genotoxic and oxidative stressThe many functions of APE1/Ref-1: not only a DNA repair enzymeIdentification of a novel potential antitumor activity of gossypol as an APE1/Ref-1 inhibitor.Redox regulation of DNA repair: implications for human health and cancer therapeutic development.Suppression of choroidal neovascularization through inhibition of APE1/Ref-1 redox activity.Thalidomide-a notorious sedative to a wonder anticancer drug.APE1/Ref-1 as an emerging therapeutic target for various human diseases: phytochemical modulation of its functionsLucanthone and its derivative hycanthone inhibit apurinic endonuclease-1 (APE1) by direct protein bindingApurinic/apyrimidinic endonuclease is inversely associated with response to radiotherapy in pediatric ependymoma.Inhibition of the redox function of APE1/Ref-1 in myeloid leukemia cell lines results in a hypersensitive response to retinoic acid-induced differentiation and apoptosis.Survey of the year 2000 commercial optical biosensor literature.Functional analysis of tanshinone IIA that blocks the redox function of human apurinic/apyrimidinic endonuclease 1/redox factor-1.Target identification of small molecules based on chemical biology approaches.Target identification for small bioactive molecules: finding the needle in the haystack.Teratogenic effects of thalidomide: molecular mechanisms.Functional analysis of novel analogues of E3330 that block the redox signaling activity of the multifunctional AP endonuclease/redox signaling enzyme APE1/Ref-1.Interactions of apurinic/apyrimidinic endonuclease with a redox inhibitor: evidence for an alternate conformation of the enzyme.The flavonoid apigenin downregulates CDK1 by directly targeting ribosomal protein S9.The redox function of APE1 is involved in the differentiation process of stem cells toward a neuronal cell fate.Proteome interrogation using nanoprobes to identify targets of a cancer-killing molecule.Inhibition of APE1/Ref-1 redox activity rescues human retinal pigment epithelial cells from oxidative stress and reduces choroidal neovascularization.Impact of APE1/Ref-1 redox inhibition on pancreatic tumor growthKnock-in reconstitution studies reveal an unexpected role of Cys-65 in regulating APE1/Ref-1 subcellular trafficking and functionGenomics and proteomics tools for compound mode-of-action studies in drug discovery.Characterization of the redox activity and disulfide bond formation in apurinic/apyrimidinic endonuclease.Nitric oxide controls nuclear export of APE1/Ref-1 through S-nitrosation of cysteines 93 and 310APE1/Ref-1 role in redox signaling: translational applications of targeting the redox function of the DNA repair/redox protein APE1/Ref-1.Role of the multifunctional DNA repair and redox signaling protein Ape1/Ref-1 in cancer and endothelial cells: small-molecule inhibition of the redox function of Ape1Inhibition of apurinic/apyrimidinic endonuclease I's redox activity revisited.Ape1/Ref-1 induces glial cell-derived neurotropic factor (GDNF) responsiveness by upregulating GDNF receptor alpha1 expressionOxidative stress alters base excision repair pathway and increases apoptotic response in apurinic/apyrimidinic endonuclease 1/redox factor-1 haploinsufficient mice.Apurinic/apyrimidinic endonuclease 1 alters estrogen receptor activity and estrogen-responsive gene expression.Antiprion drugs as chemical tools to uncover mechanisms of prion propagation.Human apurinic/apyrimidinic endonuclease 1.
P2860
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P2860
High-performance affinity beads for identifying drug receptors.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
2000年论文
@zh
2000年论文
@zh-cn
name
High-performance affinity beads for identifying drug receptors.
@en
type
label
High-performance affinity beads for identifying drug receptors.
@en
prefLabel
High-performance affinity beads for identifying drug receptors.
@en
P2093
P2860
P356
P1433
P1476
High-performance affinity beads for identifying drug receptors.
@en
P2093
Hatakeyama M
Hiramoto M
Kawaguchi H
P2860
P2888
P304
P356
10.1038/78496
P577
2000-08-01T00:00:00Z
P6179
1034227107