Molecular analysis of yeast and human type II topoisomerases. Enzyme-DNA and drug interactions.
about
Effects of camptothecin on double-strand break repair by non-homologous end-joining in DNA mismatch repair-deficient human colorectal cancer cell linesCharacterization of the DNA-binding domain and identification of the active site residue in the 'Gyr A' half of Leishmania donovani topoisomerase IIStructural basis of type II topoisomerase inhibition by the anticancer drug etoposideA mutation in Escherichia coli DNA gyrase conferring quinolone resistance results in sensitivity to drugs targeting eukaryotic topoisomerase IIImportance of the fourth alpha-helix within the CAP homology domain of type II topoisomerase for DNA cleavage site recognition and quinolone action.The use of divalent metal ions by type II topoisomerases.Molecular basis of the targeting of topoisomerase II-mediated DNA cleavage by VP16 derivatives conjugated to triplex-forming oligonucleotidesYeast recombination pathways triggered by topoisomerase II-mediated DNA breaks.Human RAD18 is involved in S phase-specific single-strand break repair without PCNA monoubiquitinationDNA topoisomerase II selects DNA cleavage sites based on reactivity rather than binding affinity.A mutation in human topoisomerase II alpha whose expression is lethal in DNA repair-deficient yeast cells.The alpha4 residues of human DNA topoisomerase IIalpha function in enzymatic activity and anticancer drug sensitivity.Isolation and characterization of mAMSA-hypersensitive mutants. Cytotoxicity of Top2 covalent complexes containing DNA single strand breaksIdentification of Myc-mediated death response pathways by microarray analysis.Topoisomerase inhibitors modulate expression of melanocytic antigens and enhance T cell recognition of tumor cells.Clerocidin interacts with the cleavage complex of Streptococcus pneumoniae topoisomerase IV to induce selective irreversible DNA damage.Topoisomerase II poisoning by ICRF-193.Methyleugenol and oxidative metabolites induce DNA damage and interact with human topoisomerases.Anthocyanin-rich extracts suppress the DNA-damaging effects of topoisomerase poisons in human colon cancer cells.
P2860
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P2860
Molecular analysis of yeast and human type II topoisomerases. Enzyme-DNA and drug interactions.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh
1999年學術文章
@zh-hant
name
Molecular analysis of yeast an ...... yme-DNA and drug interactions.
@en
type
label
Molecular analysis of yeast an ...... yme-DNA and drug interactions.
@en
prefLabel
Molecular analysis of yeast an ...... yme-DNA and drug interactions.
@en
P2093
P2860
P356
P1476
Molecular analysis of yeast an ...... zyme-DNA and drug interactions
@en
P2093
P2860
P304
28246-28255
P356
10.1074/JBC.274.40.28246
P407
P577
1999-10-01T00:00:00Z