Bcl-2-independent Bcr-Abl-mediated resistance to apoptosis: protection is correlated with up regulation of Bcl-xL.
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Protein phosphatase subunit G5PR is needed for inhibition of B cell receptor-induced apoptosisEnhanced phosphorylation of Nbs1, a member of DNA repair/checkpoint complex Mre11-RAD50-Nbs1, can be targeted to increase the efficacy of imatinib mesylate against BCR/ABL-positive leukemia cellsTec kinase Itk forms membrane clusters specifically in the vicinity of recruiting receptors.Signal transducer and activator of transcription (STAT)5 activation by BCR/ABL is dependent on intact Src homology (SH)3 and SH2 domains of BCR/ABL and is required for leukemogenesisMisfolding, Aggregation, and Disordered Segments in c-Abl and p53 in Human Cancer.Imaging hematopoietic precursor division in real time.Recent advances in the development of anticancer agents targeting cell death inhibitors in the Bcl-2 protein family.Lestaurtinib inhibition of the Jak/STAT signaling pathway in hodgkin lymphoma inhibits proliferation and induces apoptosisThe role of STATs in myeloid differentiation and leukemia.Transforming and tumorigenic activity of JAK2 by fusion to BCR: molecular mechanisms of action of a novel BCR-JAK2 tyrosine-kinase.Fusion tyrosine kinases induce drug resistance by stimulation of homology-dependent recombination repair, prolongation of G(2)/M phase, and protection from apoptosis.Modeling Philadelphia chromosome positive leukemias.MiR-24 promotes the survival of hematopoietic cellsAnti-rheumatic agent auranofin induced apoptosis in chronic myeloid leukemia cells resistant to imatinib through both Bcr/Abl-dependent and -independent mechanismsBCR/ABL regulates response to DNA damage: the role in resistance to genotoxic treatment and in genomic instability.Chronic myelogenous leukemia as a paradigm of early cancer and possible curative strategies.HS-543 induces apoptosis of Imatinib-resistant chronic myelogenous leukemia with T315I mutation.Expression of angiogenic factors in chronic myeloid leukaemia: role of the bcr/abl oncogene, biochemical mechanisms, and potential clinical implications.Bcl-x(L) antisense oligonucleotides radiosensitise colon cancer cells.Active Akt and functional p53 modulate apoptosis in Abelson virus-transformed pre-B cells.Regulated expression of P210 Bcr-Abl during embryonic stem cell differentiation stimulates multipotential progenitor expansion and myeloid cell fateTime-dependent effects of imatinib in human leukaemia cells: a kinetic NMR-profiling study.Divide and conquer: how asymmetric division shapes cell fate in the hematopoietic system.Bcl-xL anti-apoptotic network is dispensable for development and maintenance of CML but is required for disease progression where it represents a new therapeutic target.Nickel pyrithione induces apoptosis in chronic myeloid leukemia cells resistant to imatinib via both Bcr/Abl-dependent and Bcr/Abl-independent mechanisms.Apoptosis and autophagy: BIM as a mediator of tumour cell death in response to oncogene-targeted therapeutics.Gambogic acid induces apoptosis in imatinib-resistant chronic myeloid leukemia cells via inducing proteasome inhibition and caspase-dependent Bcr-Abl downregulation.Bcr-Abl-mediated protection from apoptosis downstream of mitochondrial cytochrome c release.A Pan-BCL2 inhibitor renders bone-marrow-resident human leukemia stem cells sensitive to tyrosine kinase inhibition.BCR-ABL: a multi-faceted promoter of DNA mutation in chronic myelogeneous leukemia.Mechanisms of heat shock response in mammals.Multidrug resistance in chronic myeloid leukaemia: how much can we learn from MDR-CML cell lines?Endogenous and exogenous fibroblast growth factor 2 support survival of chick retinal neurons by control of neuronal neuronal bcl-x(L) and bcl-2 expression through a fibroblast berowth factor receptor 1- and ERK-dependent pathway.Genomic mechanisms of p210BCR-ABL signaling: induction of heat shock protein 70 through the GATA response element confers resistance to paclitaxel-induced apoptosis.High CIP2A levels correlate with an antiapoptotic phenotype that can be overcome by targeting BCL-XL in chronic myeloid leukemia.L-amino acid oxidase isolated from Bothrops pirajai induces apoptosis in BCR-ABL-positive cells and potentiates imatinib mesylate effect.Small GTPase RAB45-mediated p38 activation in apoptosis of chronic myeloid leukemia progenitor cells.hnRNP A1 nucleocytoplasmic shuttling activity is required for normal myelopoiesis and BCR/ABL leukemogenesis.Inhibition of apoptosome formation by suppression of Hsp90beta phosphorylation in tyrosine kinase-induced leukemias.Mechanisms of cellular resistance to imatinib in human chronic myeloid leukemia cells.
P2860
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P2860
Bcl-2-independent Bcr-Abl-mediated resistance to apoptosis: protection is correlated with up regulation of Bcl-xL.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh
1998年學術文章
@zh-hant
name
Bcl-2-independent Bcr-Abl-medi ...... with up regulation of Bcl-xL.
@en
type
label
Bcl-2-independent Bcr-Abl-medi ...... with up regulation of Bcl-xL.
@en
prefLabel
Bcl-2-independent Bcr-Abl-medi ...... with up regulation of Bcl-xL.
@en
P2093
P356
P1433
P1476
Bcl-2-independent Bcr-Abl-medi ...... d with up regulation of Bcl-xL
@en
P2093
Amarante-Mendes GP
McGahon AJ
Nishioka WK
P2888
P304
P356
10.1038/SJ.ONC.1201664
P407
P577
1998-03-01T00:00:00Z
P5875
P6179
1024265617