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An Epithelial Integrin Regulates the Amplitude of Protective Lung Interferon Responses against Multiple Respiratory PathogensThe rising incidence of idiopathic pulmonary fibrosis in the U.KCyclooxygenase-2 deficiency results in a loss of the anti-proliferative response to transforming growth factor-beta in human fibrotic lung fibroblasts and promotes bleomycin-induced pulmonary fibrosis in miceInvestigating lung responses with functional hyperpolarized xenon-129 MRI in an ex vivo rat model of asthmaLigation of protease-activated receptor 1 enhances alpha(v)beta6 integrin-dependent TGF-beta activation and promotes acute lung injury.Influenza promotes collagen deposition via αvβ6 integrin-mediated transforming growth factor β activation.Severity of lung injury in cyclooxygenase-2-deficient mice is dependent on reduced prostaglandin E(2) production.Integrin αvβ5-mediated TGF-β activation by airway smooth muscle cells in asthmaReducing affinity of αvβ8 interactions with latent TGFβ: dialling down fibrosis.Amplification of TGFβ Induced ITGB6 Gene Transcription May Promote Pulmonary FibrosisReduced Ets Domain-containing Protein Elk1 Promotes Pulmonary Fibrosis via Increased Integrin αvβ6 ExpressionTNFα promotes CAR-dependent migration of leukocytes across epithelial monolayers.Secretory leukocyte protease inhibitor gene deletion alters bleomycin-induced lung injury, but not development of pulmonary fibrosis.Role of integrin-mediated TGFbeta activation in the pathogenesis of pulmonary fibrosis.The pathogenesis of idiopathic pulmonary fibrosis.In search of the fibrotic epithelial cell: opportunities for a collaborative network.Novel approaches to pulmonary fibrosis.Molecular Endotyping of Pulmonary Fibrosis.An Official American Thoracic Society Workshop Report: Use of Animal Models for the Preclinical Assessment of Potential Therapies for Pulmonary Fibrosis.Acute Exacerbation of Idiopathic Pulmonary Fibrosis. An International Working Group Report.Repression of IP-10 by interactions between histone deacetylation and hypermethylation in idiopathic pulmonary fibrosisIPF: Moving from Idiopathic to Infectious Pulmonary Fibrosis?A central role for G9a and EZH2 in the epigenetic silencing of cyclooxygenase-2 in idiopathic pulmonary fibrosis.αvβ6 integrin may be a potential prognostic biomarker in interstitial lung disease.Assessment of the effect of potential antifibrotic compounds on total and αVβ6 integrin-mediated TGF-β activation.Caffeine inhibits TGFβ activation in epithelial cells, interrupts fibroblast responses to TGFβ, and reduces established fibrosis in ex vivo precision-cut lung slicesLysophosphatidic acid induces alphavbeta6 integrin-mediated TGF-beta activation via the LPA2 receptor and the small G protein G alpha(q).Cyclooxygenase-2 overexpression, using an integrin-targeted gene delivery system (the LID vector), inhibits fibroblast proliferation in vitro and leads to increased prostaglandin E(2) in the lung.Efficient transfection of non-proliferating human airway epithelial cells with a synthetic vector system.Climate change and lung health: the challenge for a new president.Biophysical characterization of an integrin-targeted non-viral vector.Formation of LID vector complexes in water alters physicochemical properties and enhances pulmonary gene expression in vivo.An integrin-targeted non-viral vector for pulmonary gene therapy.Genetic variants associated with susceptibility to idiopathic pulmonary fibrosis in people of European ancestry: a genome-wide association study.Mapping the future for pulmonary fibrosis: report from the 17th International Colloquium on Lung and Airway Fibrosis.Presence of a prothrombotic state in people with idiopathic pulmonary fibrosis: a population-based case-control study.Tryptase activates TGFbeta in human airway smooth muscle cells via direct proteolysis.Interplay Between EZH2 and G9a Regulates CXCL10 Gene Repression in Idiopathic Pulmonary Fibrosis.ECM Crosslinking Enhances Fibroblast Growth and Protects Against Matrix Proteolysis in Lung Fibrosis.A big beautiful wall against infection.
P50
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P50
description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Gisli Jenkins
@ast
Gisli Jenkins
@en
Gisli Jenkins
@es
Gisli Jenkins
@nl
Gisli Jenkins
@sl
type
label
Gisli Jenkins
@ast
Gisli Jenkins
@en
Gisli Jenkins
@es
Gisli Jenkins
@nl
Gisli Jenkins
@sl
prefLabel
Gisli Jenkins
@ast
Gisli Jenkins
@en
Gisli Jenkins
@es
Gisli Jenkins
@nl
Gisli Jenkins
@sl
P1053
R-8143-2017
P106
P1153
57052267200
P31
P3829
P496
0000-0002-7929-2119
P569
2000-01-01T00:00:00Z