Inducible enhancement of memory storage and synaptic plasticity in transgenic mice expressing an inhibitor of ATF4 (CREB-2) and C/EBP proteins.
about
Pharmacological brake-release of mRNA translation enhances cognitive memoryMitosin/CENP-F as a negative regulator of activating transcription factor-4Chronic enhancement of CREB activity in the hippocampus interferes with the retrieval of spatial informationGenes and signaling pathways involved in memory enhancement in mutant miceSpecific downregulation of hippocampal ATF4 reveals a necessary role in synaptic plasticity and memoryReview: Modulating the unfolded protein response to prevent neurodegeneration and enhance memoryOxidative stress, unfolded protein response, and apoptosis in developmental toxicityC/EBPbeta couples dopamine signalling to substance P precursor gene expression in striatal neuronesThe DISC locus in psychiatric illnessTranscription factors in long-term memory and synaptic plasticityMEF2C, a transcription factor that facilitates learning and memory by negative regulation of synapse numbers and functionIMPACT, a protein preferentially expressed in the mouse brain, binds GCN1 and inhibits GCN2 activationDysregulation of presynaptic calcium and synaptic plasticity in a mouse model of 22q11 deletion syndrome.Allele-specific programming of Npy and epigenetic effects of physical activity in a genetic model of depressionTranslational control of hippocampal synaptic plasticity and memory by the eIF2alpha kinase GCN2Translational control by eIF2α kinases in long-lasting synaptic plasticity and long-term memory.Synthetic microRNA-mediated downregulation of Nogo-A in transgenic rats reveals its role as regulator of synaptic plasticity and cognitive functionBrain-specific disruption of the eIF2α kinase PERK decreases ATF4 expression and impairs behavioral flexibility.Nuclear DISC1 regulates CRE-mediated gene transcription and sleep homeostasis in the fruit fly.eIF2alpha phosphorylation bidirectionally regulates the switch from short- to long-term synaptic plasticity and memory.Drosophila SLC22A Transporter Is a Memory Suppressor Gene that Influences Cholinergic Neurotransmission to the Mushroom Bodies.The DLK-1 kinase promotes mRNA stability and local translation in C. elegans synapses and axon regenerationPhosphodiesterase type 4 inhibition does not restore ocular dominance plasticity in a ferret model of fetal alcohol spectrum disorders.Blockade of GABA(B) receptors completely reverses age-related learning impairment.PERK mediates eIF2α phosphorylation responsible for BACE1 elevation, CREB dysfunction and neurodegeneration in a mouse model of Alzheimer's disease.Interaction between long-term potentiation and depression in CA1 synapses: temporal constrains, functional compartmentalization and protein synthesis.Mechanisms of induction and maintenance of spike-timing dependent plasticity in biophysical synapse modelsControl of activating transcription factor 4 (ATF4) persistence by multisite phosphorylation impacts cell cycle progression and neurogenesis.Autism spectrum disorder is related to endoplasmic reticulum stress induced by mutations in the synaptic cell adhesion molecule, CADM1.cJun and CREB2 in the postsynaptic neuron contribute to persistent long-term facilitation at a behaviorally relevant synapse.The molecular and cellular biology of enhanced cognition.Deletion of the eIF2α Kinase GCN2 fails to rescue the memory decline associated with Alzheimer's disease.Activating transcription factor 4, a mediator of the integrated stress response, is increased in the dorsal root ganglia following painful facet joint distraction.Pharmacological dimerization and activation of the exchange factor eIF2B antagonizes the integrated stress response.Dynamics of a minimal model of interlocked positive and negative feedback loops of transcriptional regulation by cAMP-response element binding proteinsMemory enhancement: consolidation, reconsolidation and insulin-like growth factor 2The impact of the unfolded protein response on human diseaseGene expression in animals with different acute responses to ethanol.PERK Regulates Working Memory and Protein Synthesis-Dependent Memory Flexibility.Differential translation and fragile X syndrome.
P2860
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P2860
Inducible enhancement of memory storage and synaptic plasticity in transgenic mice expressing an inhibitor of ATF4 (CREB-2) and C/EBP proteins.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh
2003年學術文章
@zh-hant
name
Inducible enhancement of memor ...... 4 (CREB-2) and C/EBP proteins.
@en
Inducible enhancement of memor ...... xpressing an inhibitor of ATF4
@nl
type
label
Inducible enhancement of memor ...... 4 (CREB-2) and C/EBP proteins.
@en
Inducible enhancement of memor ...... xpressing an inhibitor of ATF4
@nl
prefLabel
Inducible enhancement of memor ...... 4 (CREB-2) and C/EBP proteins.
@en
Inducible enhancement of memor ...... xpressing an inhibitor of ATF4
@nl
P2093
P50
P1433
P1476
Inducible enhancement of memor ...... 4 (CREB-2) and C/EBP proteins.
@en
P2093
Amanda L Yonan
Dusan Bartsch
Eric R Kandel
Gaël Malleret
Isabel A Muzzio
Michael B Grody
Miguel Verbitsky
Svetlana Vronskaya
T Conrad Gilliam
P304
P356
10.1016/S0896-6273(03)00501-4
P407
P577
2003-08-01T00:00:00Z