The H2B ubiquitin ligase RNF40 cooperates with SUPT16H to induce dynamic changes in chromatin structure during DNA double-strand break repair.
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RNF20-SNF2H Pathway of Chromatin Relaxation in DNA Double-Strand Break RepairEpigenetic plasticity: a central regulator of epithelial-to-mesenchymal transition in cancerTherapeutic targeting of the MYC signal by inhibition of histone chaperone FACT in neuroblastoma.Histone ubiquitylation and its roles in transcription and DNA damage responseA positive feedback loop links opposing functions of P-TEFb/Cdk9 and histone H2B ubiquitylation to regulate transcript elongation in fission yeastRas/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascade inhibitors: how mutations can result in therapy resistance and how to overcome resistance.A subset of histone H2B genes produces polyadenylated mRNAs under a variety of cellular conditions.Zinc finger protein 668 interacts with Tip60 to promote H2AX acetylation after DNA damageHigh mobility group protein-mediated transcription requires DNA damage marker γ-H2AX.RNF20 Links Histone H2B Ubiquitylation with Inflammation and Inflammation-Associated CancerThe SAGA Deubiquitination Module Promotes DNA Repair and Class Switch Recombination through ATM and DNAPK-Mediated γH2AX Formation.The enigmatic role of H2Bub1 in cancer.The RING finger domain E3 ubiquitin ligases BRCA1 and the RNF20/RNF40 complex in global loss of the chromatin mark histone H2B monoubiquitination (H2Bub1) in cell line models and primary high-grade serous ovarian cancer.Cotranscriptional histone H2B monoubiquitylation is tightly coupled with RNA polymerase II elongation rate.SETD2 is required for DNA double-strand break repair and activation of the p53-mediated checkpoint.SUPT6H controls estrogen receptor activity and cellular differentiation by multiple epigenomic mechanisms.Radiation-induced alterations of histone post-translational modification levels in lymphoblastoid cell linesPhosphorylation by cyclin-dependent kinase-9 controls ubiquitin-conjugating enzyme-2A function.Loss of CHD1 causes DNA repair defects and enhances prostate cancer therapeutic responsiveness.Histone Chaperone SSRP1 is Essential for Wnt Signaling Pathway Activity During Osteoblast Differentiation.RNF40 regulates gene expression in an epigenetic context-dependent manner.Loss of H2Bub1 Expression is Linked to Poor Prognosis in Nodal Negative Colorectal Cancers.Getting down to the FACT: therapeutic targeting of MYC-dependent tumors.Variation in Recombination Rate and Its Genetic Determinism in Sheep Populations.Chemo-Genetic Interactions Between Histone Modification and the Antiproliferation Drug AICAR Are Conserved in Yeast and Humans.Identification of a histone family gene signature for predicting the prognosis of cervical cancer patients.let-7b and let-7c microRNAs promote histone H2B ubiquitylation and inhibit cell migration by targeting multiple components of the H2B deubiquitylation machinery.H2B ubiquitination: Conserved molecular mechanism, diverse physiologic functions of the E3 ligase during meiosis.Complex DNA Damage Induced by High Linear Energy Transfer Alpha-Particles and Protons Triggers a Specific Cellular DNA Damage Response.PRPS1 silencing reverses cisplatin resistance in human breast cancer cells.
P2860
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P2860
The H2B ubiquitin ligase RNF40 cooperates with SUPT16H to induce dynamic changes in chromatin structure during DNA double-strand break repair.
description
2011 nî lūn-bûn
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2011年の論文
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2011年学术文章
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2011年学术文章
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2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
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2011年學術文章
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2011年學術文章
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2011年學術文章
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name
The H2B ubiquitin ligase RNF40 ...... NA double-strand break repair.
@en
The H2B ubiquitin ligase RNF40 ...... NA double-strand break repair.
@nl
type
label
The H2B ubiquitin ligase RNF40 ...... NA double-strand break repair.
@en
The H2B ubiquitin ligase RNF40 ...... NA double-strand break repair.
@nl
prefLabel
The H2B ubiquitin ligase RNF40 ...... NA double-strand break repair.
@en
The H2B ubiquitin ligase RNF40 ...... NA double-strand break repair.
@nl
P356
P1433
P1476
The H2B ubiquitin ligase RNF40 ...... DNA double-strand break repair
@en
P2093
Andrei Shchebet
Vijayalakshmi Kari
P304
P356
10.4161/CC.10.20.17769
P577
2011-10-15T00:00:00Z