Development of lipidoid-siRNA formulations for systemic delivery to the liver. - Wikidata - wikimedia - TriplyDB

Development of lipidoid-siRNA formulations for systemic delivery to the liver.

Development of lipidoid-siRNA formulations for systemic delivery to the liver.

http://www.wikidata.org/entity/Q39506235

about

Drug delivery trends in clinical trials and translational medicine: challenges and opportunities in the delivery of nucleic acid-based therapeutics Nucleic acid delivery: the missing pieces of the puzzle?Delivery of oligonucleotides with lipid nanoparticles Achieving HIV-1 Control through RNA-Directed Gene Regulation Lipid-Based Nanocarriers for RNA Delivery Lipid-based vectors for siRNA delivery Mechanistically probing lipid-siRNA nanoparticle-associated toxicities identifies Jak inhibitors effective in mitigating multifaceted toxic responses.Lipid-like materials for low-dose, in vivo gene silencing Nanometer-scale siRNA carriers incorporating peptidomimetic oligomers: physical characterization and biological activity.Intranasal drug delivery of small interfering RNA targeting Beclin1 encapsulated with polyethylenimine (PEI) in mouse brain to achieve HIV attenuation.Drug delivery-mediated control of RNA immunostimulation SH2 modified STAT1 induces HLA-I expression and improves IFN-γ signaling in IFN-α resistant HCV replicon cells.The roles of individual mammalian argonautes in RNA interference in vivo.An amino acid-based amphoteric liposomal delivery system for systemic administration of siRNA.A status report on RNAi therapeutics.Targeted delivery of RNAi therapeutics with endogenous and exogenous ligand-based mechanisms.Combinatorial library of lipidoids for in vitro DNA delivery.Noninvasive imaging of lipid nanoparticle-mediated systemic delivery of small-interfering RNA to the liver.Formulation of Small Activating RNA Into Lipidoid Nanoparticles Inhibits Xenograft Prostate Tumor Growth by Inducing p21 Expression.Loss of α-catenin elicits a cholestatic response and impairs liver regeneration.Rational design of a biomimetic cell penetrating peptide library.High-density lipoprotein facilitates in vivo delivery of α-tocopherol-conjugated short-interfering RNA to the brain.Possibilities for RNA interference in developing hepatitis C virus therapeutics.Ionizable amphiphilic dendrimer-based nanomaterials with alkyl-chain-substituted amines for tunable siRNA delivery to the liver endothelium in vivo Combinatorial library strategies for synthesis of cationic lipid-like nanoparticles and their potential medical applications.Delivery of siRNA to the mouse lung via a functionalized lipopolyamine.Overcoming the challenges in administering biopharmaceuticals: formulation and delivery strategies.Identification of siRNA delivery enhancers by a chemical library screen.Calcium phosphate nanoparticles with an asymmetric lipid bilayer coating for siRNA delivery to the tumor Biocompatible and colloidally stabilized mPEG-PE/calcium phosphate hybrid nanoparticles loaded with siRNAs targeting tumors.Delivery of multiple siRNAs using lipid-coated PLGA nanoparticles for treatment of prostate cancer Specific hepatic delivery of procollagen α1(I) small interfering RNA in lipid-like nanoparticles resolves liver fibrosis Galactosylated Lipidoid Nanoparticles for Delivery of Small Interfering RNA to Inhibit Hepatitis C Viral Replication In Vivo.Oxime ether lipids containing hydroxylated head groups are more superior siRNA delivery agents than their nonhydroxylated counterparts.Targeted p21WAF1/CIP1 activation by RNAa inhibits hepatocellular carcinoma cells.Maximizing the potency of siRNA lipid nanoparticles for hepatic gene silencing in vivo.Effect of surface properties on liposomal siRNA delivery.Unique gene-silencing and structural properties of 2'-fluoro-modified siRNAs.Development of siRNA-probes for studying intracellular trafficking of siRNA nanoparticles.Lipid-like Nanoparticles for Small Interfering RNA Delivery to Endothelial Cells

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P2860

Development of lipidoid-siRNA formulations for systemic delivery to the liver.

http://www.wikidata.org/entity/Q39506235

description

2009 nî lūn-bûn

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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2009年论文

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2009年论文

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name

Development of lipidoid-siRNA formulations for systemic delivery to the liver.

@en

Development of lipidoid-siRNA formulations for systemic delivery to the liver.

@nl

type

label

Development of lipidoid-siRNA formulations for systemic delivery to the liver.

@en

Development of lipidoid-siRNA formulations for systemic delivery to the liver.

@nl

prefLabel

Development of lipidoid-siRNA formulations for systemic delivery to the liver.

@en

Development of lipidoid-siRNA formulations for systemic delivery to the liver.

@nl

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P1433

Molecular Therapy

P1476

Development of lipidoid-siRNA formulations for systemic delivery to the liver.

@en

P2093

Akin Akinc

http://www.w3.org/2001/XMLSchema#string

Christina Gamba-Vitalo

http://www.w3.org/2001/XMLSchema#string

Daniel G Anderson

http://www.w3.org/2001/XMLSchema#string

Elizaveta S Leshchiner

http://www.w3.org/2001/XMLSchema#string

J Robert Dorkin

http://www.w3.org/2001/XMLSchema#string

June Qin

http://www.w3.org/2001/XMLSchema#string

K Narayanannair Jayaprakash

http://www.w3.org/2001/XMLSchema#string

Kallanthottathil G Rajeev

http://www.w3.org/2001/XMLSchema#string

Martin Maier

http://www.w3.org/2001/XMLSchema#string

Michael Goldberg

http://www.w3.org/2001/XMLSchema#string

P2860

Stealth liposomes: review of the basic science, rationale, and clinical applications, existing and potential

Systemic leukocyte-directed siRNA delivery revealing cyclin D1 as an anti-inflammatory target

A combinatorial library of lipid-like materials for delivery of RNAi therapeutics.

Lipid-based systems for the intracellular delivery of genetic drugs.

Endosomes, lysosomes: their implication in gene transfer.

Efficient delivery of small interfering RNA to bone-metastatic tumors by using atelocollagen in vivo.

Potent and persistent in vivo anti-HBV activity of chemically modified siRNAs.

Development of non-viral vectors for systemic gene delivery.

Biodegradable nanoparticles for drug and gene delivery to cells and tissue.

Targeted nucleic acid delivery into tumors: new avenues for cancer therapy.

P304

872-879

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scholarly article

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10.1038/MT.2009.36

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5

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17

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Robert Samuel Langer, Jr.

Victor Koteliansky

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2009-03-03T00:00:00Z

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24175205

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19259063

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2835134

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