about
Identification of a cDNA for a human high-molecular-weight B-cell growth factorImpaired immunoglobulin gene rearrangement in mice lacking the IL-7 receptorCloning and characterization of HUPF1, a human homolog of the Saccharomyces cerevisiae nonsense mRNA-reducing UPF1 proteinmRNA transcripts initiating within the human immunoglobulin mu heavy chain enhancer region contain a non-translatable exon and are extremely heterogeneous at the 5' endEpigenetic repression of the Igk locus by STAT5-mediated recruitment of the histone methyltransferase Ezh2Cloning, functional characterization, and mechanism of action of the B-cell-specific transcriptional coactivator OCA-BBasal immunoglobulin signaling actively maintains developmental stage in immature B cells.Expression of human AID in yeast induces mutations in context similar to the context of somatic hypermutation at G-C pairs in immunoglobulin genesClosely related antibody receptors exploit fundamentally different strategies for steroid recognitionCDR-H3 Diversity Is Not Required for Antigen Recognition by Synthetic AntibodiesRORgammaT, a thymus-specific isoform of the orphan nuclear receptor RORgamma / TOR, is up-regulated by signaling through the pre-T cell receptor and binds to the TEA promoterConservation of an immunoglobulin variable-region gene family indicates a specific, noncoding functionThe adaptor protein Shc plays a key role during early B cell developmentImmunoglobulin heavy chain gene expression in peripheral blood B lymphocytes.Chromosomal organization of the heavy chain variable region gene segments comprising the human fetal antibody repertoire.Chromosomal translocations joining LCK and TCRB loci in human T cell leukemia.Isolation of coordinately regulated genes that are expressed in discrete stages of B-cell developmentEvolution of immunoglobulin light chain genes: analysis of Xenopus IgL isotypes and their contribution to antibody diversity.Analysis of the expression immunoglobulin gene repertoire by screening libraries derived from PCR-amplified cDNA.Isolation of scid pre-B cells that rearrange kappa light chain genes: formation of normal signal and abnormal coding joinsN-myc transgene promotes B lymphoid proliferation, elicits lymphomas and reveals cross-regulation with c-myc.Molecular cloning of the primary IgH repertoire: a quantitative analysis of VH gene usage in adult miceGenetic basis of the antibody repertoire in Xenopus: analysis of the Vh diversity.The chromosomal distribution of mouse odorant receptor genes.Stochastic pairing of heavy-chain and kappa light-chain variable gene families occurs in polyclonally activated B cellsA recombinase from Drosophila melanogaster embryos.Sequence homologies, N sequence insertion and JH gene utilization in VHDJH joining: implications for the joining mechanism and the ontogenetic timing of Ly1 B cell and B-CLL progenitor generationRearrangement by inversion of a T-cell receptor delta variable region gene located 3' of the delta constant region genePossible deletion of a developmentally regulated heavy-chain variable region gene in autoimmune diseases.Isotype switching by a microinjected mu immunoglobulin heavy chain gene in transgenic miceLight-chain gene expression before heavy-chain gene rearrangement in pre-B cells transformed by Epstein-Barr virusA highly informative probe for two polymorphic Vh gene regions that contain one or more autoantibody-associated Vh genesRapid, nonradioactive detection of clonal T-cell receptor gene rearrangements in lymphoid neoplasms.Separate elements control DJ and VDJ rearrangement in a transgenic recombination substrateA novel regulatory myosin light chain gene distinguishes pre-B cell subsets and is IL-7 inducible.CD4+CD25+ regulatory T cells in autoimmune arthritis.A dominant-negative transgene defines a role for p56lck in thymopoiesis.TCR beta and TCR alpha gene enhancers confer tissue- and stage-specificity on V(D)J recombination events.Evidence that the V kappa III gene usage is nonstochastic in both adult and newborn peripheral B cells and that peripheral CD5+ adult B cells are oligoclonal.An idiotypic marker associated with a germ-line encoded kappa light chain variable region that predominates the vaccine-induced human antibody response to the Haemophilus influenzae b polysaccharide
P2860
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P2860
description
1987 nî lūn-bûn
@nan
1987年の論文
@ja
1987年論文
@yue
1987年論文
@zh-hant
1987年論文
@zh-hk
1987年論文
@zh-mo
1987年論文
@zh-tw
1987年论文
@wuu
1987年论文
@zh
1987年论文
@zh-cn
name
Development of the primary antibody repertoire.
@en
Development of the primary antibody repertoire.
@nl
type
label
Development of the primary antibody repertoire.
@en
Development of the primary antibody repertoire.
@nl
prefLabel
Development of the primary antibody repertoire.
@en
Development of the primary antibody repertoire.
@nl
P2093
P356
P1433
P1476
Development of the primary antibody repertoire.
@en
P2093
Blackwell TK
Yancopoulos GD
P304
P356
10.1126/SCIENCE.3317825
P407
P577
1987-11-01T00:00:00Z