Homologous recombination is required for the viability of rad27 mutants.
about
Cdk1 targets Srs2 to complete synthesis-dependent strand annealing and to promote recombinational repairThe RAD2 domain of human exonuclease 1 exhibits 5' to 3' exonuclease and flap structure-specific endonuclease activitiesThe 3'-->5' exonuclease of DNA polymerase delta can substitute for the 5' flap endonuclease Rad27/Fen1 in processing Okazaki fragments and preventing genome instabilityRad52 forms DNA repair and recombination centers during S phase.ELG1, a yeast gene required for genome stability, forms a complex related to replication factor CGenetic analysis of Saccharomyces cerevisiae H2A serine 129 mutant suggests a functional relationship between H2A and the sister-chromatid cohesion partners Csm3-Tof1 for the repair of topoisomerase I-induced DNA damage.The nuclease activity of Mre11 is required for meiosis but not for mating type switching, end joining, or telomere maintenance.Unligated Okazaki Fragments Induce PCNA Ubiquitination and a Requirement for Rad59-Dependent Replication Fork Progression.Saccharomyces cerevisiae Rrm3p DNA helicase promotes genome integrity by preventing replication fork stalling: viability of rrm3 cells requires the intra-S-phase checkpoint and fork restart activitiesRole of RAD52 epistasis group genes in homologous recombination and double-strand break repairRole of the Schizosaccharomyces pombe F-Box DNA helicase in processing recombination intermediatesTwo different Swi5-containing protein complexes are involved in mating-type switching and recombination repair in fission yeast.Rad51 protein controls Rad52-mediated DNA annealing.Post-replication repair suppresses duplication-mediated genome instabilityRad52/Rad59-dependent recombination as a means to rectify faulty Okazaki fragment processing.Pathways and Mechanisms that Prevent Genome Instability in Saccharomyces cerevisiaeMitotic recombination in yeast: elements controlling its incidence.A novel role in DNA metabolism for the binding of Fen1/Rad27 to PCNA and implications for genetic risk.Novel function of Rad27 (FEN-1) in restricting short-sequence recombination.Identification of rad27 mutations that confer differential defects in mutation avoidance, repeat tract instability, and flap cleavageBacteriophage T4 rnh (RNase H) null mutations: effects on spontaneous mutation and epistatic interaction with rII mutations.Okazaki fragment maturation in yeast. I. Distribution of functions between FEN1 AND DNA2.Ku prevents Exo1 and Sgs1-dependent resection of DNA ends in the absence of a functional MRX complex or Sae2The Schizosaccharomyces pombe rad60 gene is essential for repairing double-strand DNA breaks spontaneously occurring during replication and induced by DNA-damaging agents.Rescue of arrested replication forks by homologous recombinationA new Saccharomyces cerevisiae strain with a mutant Smt3-deconjugating Ulp1 protein is affected in DNA replication and requires Srs2 and homologous recombination for its viability.Alternate pathways involving Sgs1/Top3, Mus81/ Mms4, and Srs2 prevent formation of toxic recombination intermediates from single-stranded gaps created by DNA replication.Genetic instability induced by overexpression of DNA ligase I in budding yeast.A novel allele of RAD52 that causes severe DNA repair and recombination deficiencies only in the absence of RAD51 or RAD59Saccharomyces cerevisiae rad51 mutants are defective in DNA damage-associated sister chromatid exchanges but exhibit increased rates of homology-directed translocationsOverlapping functions of the Saccharomyces cerevisiae Mre11, Exo1 and Rad27 nucleases in DNA metabolismThe Rad27 (Fen-1) nuclease inhibits Ty1 mobility in Saccharomyces cerevisiae.Srs2 overexpression reveals a helicase-independent role at replication forks that requires diverse cell functionsAlleles of the homologous recombination gene, RAD59, identify multiple responses to disrupted DNA replication in Saccharomyces cerevisiaeComplex minisatellite rearrangements generated in the total or partial absence of Rad27/hFEN1 activity occur in a single generation and are Rad51 and Rad52 dependent.Two modes of FEN1 binding to PCNA regulated by DNA.Inverted Alu repeats unstable in yeast are excluded from the human genome.Nuclease-deficient FEN-1 blocks Rad51/BRCA1-mediated repair and causes trinucleotide repeat instabilityThe Saccharomyces cerevisiae Dna2 can function as a sole nuclease in the processing of Okazaki fragments in DNA replicationCancer predisposition and hematopoietic failure in Rad50(S/S) mice.
P2860
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P2860
Homologous recombination is required for the viability of rad27 mutants.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Homologous recombination is required for the viability of rad27 mutants.
@en
Homologous recombination is required for the viability of rad27 mutants.
@nl
type
label
Homologous recombination is required for the viability of rad27 mutants.
@en
Homologous recombination is required for the viability of rad27 mutants.
@nl
prefLabel
Homologous recombination is required for the viability of rad27 mutants.
@en
Homologous recombination is required for the viability of rad27 mutants.
@nl
P356
P1476
Homologous recombination is required for the viability of rad27 mutants.
@en
P2093
L S Symington
P304
P356
10.1093/NAR/26.24.5589
P577
1998-12-01T00:00:00Z