TRAIL-activated stress kinases suppress apoptosis through transcriptional upregulation of MCL-1.
about
Overcoming chemotherapy drug resistance by targeting inhibitors of apoptosis proteins (IAPs)Molecular targets for selective killing of TRAIL-resistant leukemic cells.SB202190-induced cell type-specific vacuole formation and defective autophagy do not depend on p38 MAP kinase inhibition.Modeling dynamics of cell-to-cell variability in TRAIL-induced apoptosis explains fractional killing and predicts reversible resistanceThe downregulation of Mcl-1 via USP9X inhibition sensitizes solid tumors to Bcl-xl inhibition.Characterization of Potent SMAC Mimetics that Sensitize Cancer Cells to TNF Family-Induced ApoptosisQuercetin-mediated Mcl-1 and survivin downregulation restores TRAIL-induced apoptosis in non-Hodgkin's lymphoma B cells.Antiapoptotic signaling via MCL1 confers resistance to caspase-3-mediated apoptotic cell death in the pregnant human uterine myocyte.miR-22 and miR-29a Are Members of the Androgen Receptor Cistrome Modulating LAMC1 and Mcl-1 in Prostate Cancer.Cells surviving fractional killing by TRAIL exhibit transient but sustainable resistance and inflammatory phenotypes.Targeting TNF-related apoptosis-inducing ligand (TRAIL) receptor by natural products as a potential therapeutic approach for cancer therapyβ-Elemene: Mechanistic Studies on Cancer Cell Interaction and Its Chemosensitization EffectNon-canonical kinase signaling by the death ligand TRAIL in cancer cells: discord in the death receptor family.Surviving apoptosis: life-death signaling in single cells.The PI3 kinase inhibitor NVP-BKM120 induces GSK3/FBXW7-dependent Mcl-1 degradation, contributing to induction of apoptosis and enhancement of TRAIL-induced apoptosis.Ionizing radiation-inducible microRNA miR-193a-3p induces apoptosis by directly targeting Mcl-1.MAPK p38 and JNK have opposing activities on TRAIL-induced apoptosis activation in NSCLC H460 cells that involves RIP1 and caspase-8 and is mediated by Mcl-1.Trail down-regulates the release of osteoprotegerin (OPG) by primary stromal cells.UMI-77 primes glioma cells for TRAIL-induced apoptosis by unsequestering Bim and Bak from Mcl-1.In vitro and in vivo anti-leukemic effects of cladoloside C2 are mediated by activation of Fas/ceramide synthase 6/p38 kinase/c-Jun NH2-terminal kinase/caspase-8.Expression of TRAIL and Fas in Primary Hyperparathyroidism.
P2860
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P2860
TRAIL-activated stress kinases suppress apoptosis through transcriptional upregulation of MCL-1.
description
2010 nî lūn-bûn
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2010年の論文
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年學術文章
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name
TRAIL-activated stress kinases ...... ptional upregulation of MCL-1.
@en
TRAIL-activated stress kinases ...... ptional upregulation of MCL-1.
@nl
type
label
TRAIL-activated stress kinases ...... ptional upregulation of MCL-1.
@en
TRAIL-activated stress kinases ...... ptional upregulation of MCL-1.
@nl
prefLabel
TRAIL-activated stress kinases ...... ptional upregulation of MCL-1.
@en
TRAIL-activated stress kinases ...... ptional upregulation of MCL-1.
@nl
P2093
P2860
P356
P1476
TRAIL-activated stress kinases ...... ptional upregulation of MCL-1.
@en
P2093
S B Bratton
S Varadarajan
P2860
P2888
P304
P356
10.1038/CDD.2010.9
P577
2010-02-19T00:00:00Z
P5875
P6179
1030046114