A helical membrane-binding domain targets the Toxoplasma ROP2 family to the parasitophorous vacuole.
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Phosphorylation of immunity-related GTPases by a Toxoplasma gondii-secreted kinase promotes macrophage survival and virulenceA Conserved Non-canonical Motif in the Pseudoactive Site of the ROP5 Pseudokinase Domain Mediates Its Effect on Toxoplasma VirulenceStructure of the Toxoplasma gondii ROP18 Kinase Domain Reveals a Second Ligand Binding Pocket Required for Acute VirulenceSecreted effectors in Toxoplasma gondii and related species: determinants of host range and pathogenesis?Identification of novel proteins in Neospora caninum using an organelle purification and monoclonal antibody approachThe Toxoplasma pseudokinase ROP5 forms complexes with ROP18 and ROP17 kinases that synergize to control acute virulence in mice.Modulation of innate immunity by Toxoplasma gondii virulence effectors.Processing and secretion of ROP13: A unique Toxoplasma effector protein.Association of host mitochondria with the parasitophorous vacuole during Toxoplasma infection is not dependent on rhoptry proteins ROP2/8.Proteomic analysis of fractionated Toxoplasma oocysts reveals clues to their environmental resistanceSelective and strain-specific NFAT4 activation by the Toxoplasma gondii polymorphic dense granule protein GRA6.Integrative genomic approaches highlight a family of parasite-specific kinases that regulate host responsesSubversion of host cellular functions by the apicomplexan parasites.The rhoptry proteins ROP18 and ROP5 mediate Toxoplasma gondii evasion of the murine, but not the human, interferon-gamma response.Hammondia hammondi, an avirulent relative of Toxoplasma gondii, has functional orthologs of known T. gondii virulence genesHave it your way: how polymorphic, injected kinases and pseudokinases enable Toxoplasma to subvert host defenses.Virulence differences in Toxoplasma mediated by amplification of a family of polymorphic pseudokinases.Polymorphic family of injected pseudokinases is paramount in Toxoplasma virulenceATF6beta is a host cellular target of the Toxoplasma gondii virulence factor ROP18.Toxoplasma gondii effectors are master regulators of the inflammatory response.Rhoptry Proteins ROP5 and ROP18 Are Major Murine Virulence Factors in Genetically Divergent South American Strains of Toxoplasma gondii.The secreted kinase ROP18 defends Toxoplasma's border.Toxoplasma and Plasmodium protein kinases: roles in invasion and host cell remodelling.Bradyzoite pseudokinase 1 is crucial for efficient oral infectivity of the Toxoplasma gondii tissue cystThe arginine-rich N-terminal domain of ROP18 is necessary for vacuole targeting and virulence of Toxoplasma gondii.SAG2A protein from Toxoplasma gondii interacts with both innate and adaptive immune compartments of infected hosts.Secretion of Rhoptry and Dense Granule Effector Proteins by Nonreplicating Toxoplasma gondii Uracil Auxotrophs Controls the Development of Antitumor Immunity.The Toxoplasma gondii Rhoptry Kinome Is Essential for Chronic Infection.Toxoplasma GRA7 effector increases turnover of immunity-related GTPases and contributes to acute virulence in the mouse.Identification of three novel Toxoplasma gondii rhoptry proteins.Focus on the ringleader: the role of AMA1 in apicomplexan invasion and replication.A HT/PEXEL motif in Toxoplasma dense granule proteins is a signal for protein cleavage but not export into the host cell.The phosphoproteomes of Plasmodium falciparum and Toxoplasma gondii reveal unusual adaptations within and beyond the parasites' boundaries.Characterization of the Neospora caninum NcROP40 and NcROP2Fam-1 rhoptry proteins during the tachyzoite lytic cycle.The Rhoptry Pseudokinase ROP54 Modulates Toxoplasma gondii Virulence and Host GBP2 Loading.Continuum approaches to understanding ion and peptide interactions with the membrane.Functional Analysis of the Rhoptry Kinome during Chronic Toxoplasma gondii Infection.Demarcation of Viral Shelters Results in Destruction by Membranolytic GTPases: Antiviral Function of Autophagy Proteins and Interferon-Inducible GTPases.Inhibition of ATF6β-dependent host adaptive immune response by a Toxoplasma virulence factor ROP18.
P2860
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P2860
A helical membrane-binding domain targets the Toxoplasma ROP2 family to the parasitophorous vacuole.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh
2009年學術文章
@zh-hant
name
A helical membrane-binding dom ...... o the parasitophorous vacuole.
@en
A helical membrane-binding dom ...... o the parasitophorous vacuole.
@nl
type
label
A helical membrane-binding dom ...... o the parasitophorous vacuole.
@en
A helical membrane-binding dom ...... o the parasitophorous vacuole.
@nl
prefLabel
A helical membrane-binding dom ...... o the parasitophorous vacuole.
@en
A helical membrane-binding dom ...... o the parasitophorous vacuole.
@nl
P2860
P1433
P1476
A helical membrane-binding dom ...... o the parasitophorous vacuole.
@en
P2093
John C Boothroyd
Michael L Reese
P2860
P304
P356
10.1111/J.1600-0854.2009.00958.X
P577
2009-06-22T00:00:00Z