Phosphorylation of p27Kip1 regulates assembly and activation of cyclin D1-Cdk4 - Wikidata - wikimedia - TriplyDB

Phosphorylation of p27Kip1 regulates assembly and activation of cyclin D1-Cdk4

Phosphorylation of p27Kip1 regulates assembly and activation of cyclin D1-Cdk4

http://www.wikidata.org/entity/Q39949579

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Phosphorylation of p27Kip1 by JAK2 directly links cytokine receptor signaling to cell cycle control RSK1 drives p27Kip1 phosphorylation at T198 to promote RhoA inhibition and increase cell motility.Normal proliferation and tumorigenesis but impaired pancreatic function in mice lacking the cell cycle regulator sei1.Prediction and testing of biological networks underlying intestinal cancer The ETS family member GABPα modulates androgen receptor signalling and mediates an aggressive phenotype in prostate cancer The role of cyclooxygenase-2 in cell proliferation and cell death in human malignancies.Prolonged mechanical ventilation induces cell cycle arrest in newborn rat lung.Phosphorylation and subcellular localization of p27Kip1 regulated by hydrogen peroxide modulation in cancer cells p27: a barometer of signaling deregulation and potential predictor of response to targeted therapies.p27(Kip1), a double-edged sword in Shh-mediated medulloblastoma: Tumor accelerator and suppressor.Elevated expression of CDK4 in lung cancer.Promotion of cytoplasmic mislocalization of p27 by Helicobacter pylori in gastric cancer.Mammary epithelial-specific disruption of c-Src impairs cell cycle progression and tumorigenesis.Co-expressed Cyclin D variants cooperate to regulate proliferation of germline nuclei in a syncytium.Tyrosine phosphorylation of the p21 cyclin-dependent kinase inhibitor facilitates the development of proneural glioma.Epithelial morphological reversion drives Profilin-1-induced elevation of p27(kip1) in mesenchymal triple-negative human breast cancer cells through AMP-activated protein kinase activation.CDK4: A Key Player in the Cell Cycle, Development, and Cancer A Cdk7-Cdk4 T-loop phosphorylation cascade promotes G1 progression Platelet-derived growth factor-A regulates lung fibroblast S-phase entry through p27(kip1) and FoxO3a p27 Is a Candidate Prognostic Biomarker and Metastatic Promoter in Osteosarcoma.Sp1 phosphorylation and its regulation of gene transcription.The function of p27 KIP1 during tumor development.Fbxl12 triggers G1 arrest by mediating degradation of calmodulin kinase I.Karyopherin Alpha 1 Regulates Satellite Cell Proliferation and Survival by Modulating Nuclear Import.Targeting p27Kip1 protein: its relevance in the therapy of human cancer.Novel potent pharmacological cyclin-dependent kinase inhibitors.Tumor cell vascular mimicry: Novel targeting opportunity in melanoma.LIM domain only 2 induces glioma invasion via cytosolic p27(KIP1).Do Helper T Cell Subtypes in Lymphocytic Thyroiditis Play a Role in the Antitumor Effect?FLT3 and FLT3-ITD phosphorylate and inactivate the cyclin-dependent kinase inhibitor p27Kip1 in acute myeloid leukemia.Chronic AMD3100 antagonism of SDF-1alpha-CXCR4 exacerbates cardiac dysfunction and remodeling after myocardial infarction.Sumoylation in p27kip1 via RanBP2 promotes cancer cell growth in cholangiocarcinoma cell line QBC939.Regulation of p27Kip1 phosphorylation and G1 cell cycle progression by protein phosphatase PPM1G.The Cell Cycle Inhibitors p21Cip1 and p27Kip1 Control Proliferation but Enhance DNA Damage Resistance of Glioma Stem Cells.Definition of a Skp2-c-Myc Pathway to Expand Human Beta-cells P27Kip1 serine 10 phosphorylation determines its metabolism and interaction with cyclin-dependent kinases.c-Src regulates cell cycle proteins expression through protein kinase B/glycogen synthase kinase 3 beta and extracellular signal-regulated kinases 1/2 pathways in MCF-7 cells.Differential Regulation of G1 CDK Complexes by the Hsp90-Cdc37 Chaperone System.Cold-inducible RNA-binding protein (CIRP) induces translation of the cell-cycle inhibitor p27Kip1.Cip/Kip CDK inhibitors bind CDK4/6:CCND complexes

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Phosphorylation of p27Kip1 regulates assembly and activation of cyclin D1-Cdk4

http://www.wikidata.org/entity/Q39949579

description

2008 nî lūn-bûn

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2008年の論文

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2008年学术文章

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2008年学术文章

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2008年学术文章

@zh-hans

2008年学术文章

@zh-my

2008年学术文章

@zh-sg

2008年學術文章

@yue

2008年學術文章

@zh

2008年學術文章

@zh-hant

name

Phosphorylation of p27Kip1 regulates assembly and activation of cyclin D1-Cdk4

@en

Phosphorylation of p27Kip1 regulates assembly and activation of cyclin D1-Cdk4.

@nl

type

label

Phosphorylation of p27Kip1 regulates assembly and activation of cyclin D1-Cdk4

@en

Phosphorylation of p27Kip1 regulates assembly and activation of cyclin D1-Cdk4.

@nl

prefLabel

Phosphorylation of p27Kip1 regulates assembly and activation of cyclin D1-Cdk4

@en

Phosphorylation of p27Kip1 regulates assembly and activation of cyclin D1-Cdk4.

@nl

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Molecular and Cellular Biology

P1476

Phosphorylation of p27Kip1 regulates assembly and activation of cyclin D1-Cdk4

@en

P2093

D Dumont

http://www.w3.org/2001/XMLSchema#string

Feng Hong

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Jiyong Liang

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Joyce M Slingerland

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Kathy Han

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Michelle D Larrea

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Shan H Shao

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Thiago Da Silva

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P2860

Cdk-inhibitory activity and stability of p27Kip1 are directly regulated by oncogenic tyrosine kinases

p27 phosphorylation by Src regulates inhibition of cyclin E-Cdk2

A growth factor-dependent nuclear kinase phosphorylates p27(Kip1) and regulates cell cycle progression.

C-terminal phosphorylation controls the stability and function of p27kip1

New functional activities for the p21 family of CDK inhibitors

Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals

Altered p27(Kip1) phosphorylation, localization, and function in human epithelial cells resistant to transforming growth factor beta-mediated G(1) arrest

Novel p27(kip1) C-terminal scatter domain mediates Rac-dependent cell migration independent of cell cycle arrest functions

Transforming growth factor beta stabilizes p15INK4B protein, increases p15INK4B-cdk4 complexes, and inhibits cyclin D1-cdk4 association in human mammary epithelial cells

Down-regulation of p21WAF1/CIP1 or p27Kip1 abrogates antiestrogen-mediated cell cycle arrest in human breast cancer cells

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6462-6472

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10.1128/MCB.02300-07

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P433

20

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28

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2008-08-18T00:00:00Z

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23178293

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18710949

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P921

phosphorylation

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2577417

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