beta-Peptides as inhibitors of protein-protein interactions.
about
Protease-resistant peptide design-empowering nature's fragile warriors against HIVFoldamers as versatile frameworks for the design and evolution of functionA spiroligomer α-helix mimic that binds HDM2, penetrates human cells and stabilizes HDM2 in cell cultureA novel microtubule de-stabilizing complementarity-determining region C36L1 peptide displays antitumor activity against melanoma in vitro and in vivoBiophysical and structural characterization of a robust octameric beta-peptide bundleComparison of design strategies for promotion of beta-peptide 14-helix stability in water.A β-peptide agonist of the GLP-1 receptor, a class B GPCR.De novo design of antimicrobial polymers, foldamers, and small molecules: from discovery to practical applications.Bridged beta(3)-peptide inhibitors of p53-hDM2 complexation: correlation between affinity and cell permeability.Beta-peptides with improved affinity for hDM2 and hDMX.Positional screening and NMR structure determination of side-chain-to-side-chain cyclized β3-peptides.Mini review: protein-protein interactions in transcription: a fertile ground for helix mimetics.Peptidomimetics via modifications of amino acids and peptide bonds.Synthetic mimetics of protein secondary structure domainsProtein Synthesis with Ribosomes Selected for the Incorporation of β-Amino Acids.Cancer treatment using peptides: current therapies and future prospectsMechanical stability of helical beta-peptides and a comparison of explicit and implicit solvent models.Noncovalent modification of chymotrypsin surface using an amphiphilic polymer scaffold: implications in modulating protein function.Drugging Membrane Protein Interactions.Inhibitors of MDM2 and MDMX: a structural perspective.Inhibitors of the interactions between HIV-1 IN and the cofactor LEDGF/p75.Bacterial β-aminopeptidases: structural insights and applications for biocatalysis.Multivalent presentation of carbohydrates by 3(14)-helical peptide templates: synthesis, conformational analysis using CD spectroscopy and saccharide recognition.Constrained peptides as miniature protein structuresStructure-Based Design of Inhibitors of Protein-Protein Interactions: Mimicking Peptide Binding Epitopes.Salt-bridging effects on short amphiphilic helical structure and introducing sequence-based short beta-turn motifs.Peptides and peptidomimetics in the p53/MDM2/MDM4 circuitry - a patent review.Discovery of multiple interacting partners of gankyrin, a proteasomal chaperone and an oncoprotein--evidence for a common hot spot site at the interface and its functional relevance.The role of primary sequence in helical control compared across short α- and β(3)-peptides.Identification of a beta3-peptide HIV fusion inhibitor with improved potency in live cells.Small molecule probes to target the human Mediator complex.Molecular architecture with carbohydrate functionalized β-peptides adopting 314-helical conformation.Computational design of a β-peptide that targets transmembrane helicesComputational design of a self-assembling β-peptide oligomer.Positive allostery in metal ion binding by a cooperatively folded β-peptide bundle.Surface binding inhibitors of the SCF-KIT protein-protein interaction.Synthesis and structural characterization of sialic acid-glutamic acid hybrid foldamers as conformational surrogates of alpha-2,8-linked polysialic acid.Synthesis of functionalised aromatic oligamide rods.A synthesis of oligomeric alpha-hydroxy phenylphosphinates and a study of the conformational preferences of the dimers.One-pot efficient synthesis of N(α)-urethane-protected β- and γ-amino acids.
P2860
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P2860
beta-Peptides as inhibitors of protein-protein interactions.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
beta-Peptides as inhibitors of protein-protein interactions.
@en
beta-Peptides as inhibitors of protein-protein interactions.
@nl
type
label
beta-Peptides as inhibitors of protein-protein interactions.
@en
beta-Peptides as inhibitors of protein-protein interactions.
@nl
prefLabel
beta-Peptides as inhibitors of protein-protein interactions.
@en
beta-Peptides as inhibitors of protein-protein interactions.
@nl
P2093
P2860
P1476
beta-Peptides as inhibitors of protein-protein interactions.
@en
P2093
Alanna Schepartz
Danielle A Guarracino
Joshua A Kritzer
Olen M Stephens
Samuel K Reznik
P2860
P356
10.1016/J.BMC.2004.09.009
P407
P577
2005-01-01T00:00:00Z